Clinical trial · Interventional
Dexmedetomidine Infusion During Laparoscopic Adrenalectomy
The Effects of Perioperative Dexmedetomidine Infusion on Hemodynamic Stability During Laparoscopic Adrenalectomy for Pheochromocytoma: a Randomized Study
NCT06037135CI-TRIAL-00070249completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators planned this study to investigate the effects of dexmedetomidine administration on intraoperative hemodynamic stability in patients with pheochromocytoma.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pheochromocytoma | Adrenal Gland Pheochromocytoma | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 0.9% normal saline | Drug | — | UNRESOLVED |
| dexmedetomidine | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- dexmedetomidine group
- description
- In the dexmedetomidine group, dexmedetomidine is administered at a rate of 0.5 μg/kg/h immediately after anesthesia induction and continued until the completion of the surgery.
- interventionNames
- Drug: dexmedetomidine
- type
- ACTIVE_COMPARATOR
- label
- Control group
- description
- In the control group, a 0.9% normal saline infusion is initiated at the same rate immediately after anesthesia induction and continued until the end of the operation.
- interventionNames
- Drug: 0.9% normal saline
Primary outcomes (6)
- measure
- Intraoperative hemodynamic stability ( maximum blood pressure during surgery (systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MBP))
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. ages of 20 and 70 2. American Society of Anesthesiologists(ASA) physical status classification I to III, 3. planned laparoscopic adrenalectomy for pheochromocytoma. Exclusion Criteria: 1. emergency operation, 2. re-operation, 3. combined surgery with other departments, 4. body mass index (BMI) \>32 kg/m2, 5. history of arrhythmias (especially AV nodal block) and ventricular conduction abnormalities, 6. uncontrolled hypertension (diastolic blood pressure \>110mmHg) 7. bradycardia (heart rate \< 40 beats per minute), 8. history of heart failure, hepatic and/or renal failure, 9. history of cerebrovascular disease (cerebral hemorrhage, cerebral ischemia), 10. history of beta-blocker therapy, 10) history of uncontrolled psychiatric disease.
References
Publications (0)
Data not yet available
No reference posted for this study.