Subtype
Osteosarcoma
CI-CAN-00001321Explore in graph →
99 active trials6 approved drugs5 evidence items
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Subtype
CI-CAN-00001321Explore in graph →
Clinical trials
349 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (40)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04861948 | IBI188 Combination Therapy in Solid Tumors | terminated | Phase 1 | 9 | Innovent Biologics (Suzhou) Co. Ltd.INDUSTRY | 1 | Oct 4, 2022 | clinicaltrials |
| NCT03209869 | Treatment of Relapsed or Refractory Neuroblastoma and Osteosarcoma With Expanded Haploidentical NK Cells and Hu14.18-IL2 | withdrawn | Phase 1 | 0 | University of Wisconsin, MadisonOTHER | 1 | Sep 13, 2022 | clinicaltrials |
| NCT05515068 |
| Registry For Children, Adolescents And Adults With Osteosarcoma And Biologically Related Bone Sarcomas(COSS-Registry) |
| not yet recruiting |
| — |
| 1,000 |
| Klinikum StuttgartOTHER |
| 0 |
| Aug 25, 2022 |
| clinicaltrials |
| NCT02357810 | Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas | completed | Phase 2 | 178 | Northwestern UniversityOTHER | 1 | Jun 7, 2022 | clinicaltrials |
| NCT00634504 | Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze(LVPK) | completed | Phase 1 | 20 | BTG International Inc.OTHER | 1 | Jun 6, 2022 | clinicaltrials |
| NCT03997747 | Cancer Genome Study Using Samples From Patients Treated on Clinical Trial SHR1020-SHR-1210-II-OS(CSSG-02) | completed | — | 38 | Peking University People's HospitalOTHER | 1 | Jun 3, 2022 | clinicaltrials |
| NCT04867421 | Neutrophils in Bone Sarcomas(TANOs) | unknown | — | 25 | Université de Reims Champagne-ArdenneOTHER | 1 | May 25, 2022 | clinicaltrials |
| NCT00346164 | Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma | completed | Phase 3 | 588 | Children's Oncology GroupNETWORK | 5 | Apr 28, 2022 | clinicaltrials |
| NCT05093101 | The Prognostic Value of Serum Biomarkers in Osteosarcoma | completed | — | 600 | Istituto Ortopedico RizzoliOTHER | 1 | Apr 5, 2022 | clinicaltrials |
| NCT02013336 | Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors | unknown | Phase 1 | 30 | South Plains Oncology ConsortiumNETWORK | 1 | Mar 31, 2022 | clinicaltrials |
| NCT01190943 | DNA Biomarkers in Tissue Samples From Patients With Osteosarcoma | completed | — | 125 | Children's Oncology GroupNETWORK | 1 | Mar 28, 2022 | clinicaltrials |
| NCT02982941 | Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors | completed | Phase 1 | 25 | MacroGenicsINDUSTRY | 1 | Feb 8, 2022 | clinicaltrials |
| NCT05194605 | Predictive Models of Treatment Responses and Survival Outcomes in Patients With Osteosarcoma | unknown | — | 800 | West China HospitalOTHER | 1 | Jan 31, 2022 | clinicaltrials |
| NCT02487979 | Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma | completed | Phase 2 | 22 | National Cancer Institute (NCI)NIH | 3 | Jan 18, 2022 | clinicaltrials |
| NCT05116800 | Phase 2 Study of 9-ING-41 With Chemotherapy in Sarcoma | withdrawn | Phase 2 | 0 | Brown UniversityOTHER | 1 | Dec 7, 2021 | clinicaltrials |
| NCT04945512 | Efficacy of Epidural Analgesia in Lower Extremity Osteosarcoma | unknown | N/A | 28 | Istanbul UniversityOTHER | 1 | Nov 9, 2021 | clinicaltrials |
| NCT01176981 | Outpatient Administration of High Dose Methotrexate (HD MTX) in Patients With Osteosarcoma | completed | Phase 3 | 6 | The Hospital for Sick ChildrenOTHER | 1 | Oct 28, 2021 | clinicaltrials |
| NCT01532687 | Gemcitabine With or Without Pazopanib in Treating Patients With Refractory Soft Tissue Sarcoma | completed | Phase 2 | 54 | OHSU Knight Cancer InstituteOTHER | 1 | Sep 27, 2021 | clinicaltrials |
| NCT03298971 | The Impact of Cancer on the Physical and Psychosocial Well-being Among Childhood Osteosarcoma Survivors | unknown | — | 240 | The University of Hong KongOTHER | 1 | Sep 8, 2021 | clinicaltrials |
| NCT04757064 | Efficacy of Exercise Program on Osteosarcoma Patients | unknown | N/A | 40 | Cairo UniversityOTHER | 0 | Aug 6, 2021 | clinicaltrials |
| NCT03768076 | an Istitution Experience on Parosteal OsTeosarcoma | completed | — | 220 | Istituto Ortopedico RizzoliOTHER | 1 | Aug 5, 2021 | clinicaltrials |
| NCT04383288 | ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities | completed | — | 115 | Grupo Espanol de Investigacion en SarcomasOTHER | 1 | Aug 4, 2021 | clinicaltrials |
| NCT04886765 | A Study to Evaluate the Safety and Efficacy of ALMB-0168 in Patients With Osteosarcoma | unknown | Phase 1 / Phase 2 | 238 | AlaMab Therapeutics (Shanghai) Inc.INDUSTRY | 0 | May 14, 2021 | clinicaltrials |
| NCT04864821 | Clinical Study of CD276 Targeted Autologous Chimeric Antigen Receptor T Cell Infusion in Patients With CD276 Positive Advanced Solid Tumor | unknown | Early Phase 1 | 24 | PersonGen BioTherapeutics (Suzhou) Co., Ltd.INDUSTRY | 0 | May 6, 2021 | clinicaltrials |
| NCT02581384 | Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms Tumors | terminated | Phase 1 / Phase 2 | 5 | Dana-Farber Cancer InstituteOTHER | 1 | Apr 30, 2021 | clinicaltrials |
| NCT01759303 | Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung | terminated | Phase 2 | 12 | Emerald Clinical Inc.INDUSTRY | 1 | Apr 13, 2021 | clinicaltrials |
| NCT02159443 | Pretreatment Anti-Therapeutic Antibodies (PATA) in Patients Treated With hu14.18K322A Antibody | completed | — | 76 | St. Jude Children's Research HospitalOTHER | 1 | Nov 5, 2020 | clinicaltrials |
| NCT01987596 | Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer | terminated | Phase 3 | 23 | Barbara Ann Karmanos Cancer InstituteOTHER | 1 | Oct 29, 2020 | clinicaltrials |
| NCT03013127 | A Study of Pembrolizumab in Patients With Relapsed Or Metastatic Osteosarcoma Not Eligible for Curative Surgery(PROMO) | terminated | Phase 2 | 12 | Oslo University HospitalOTHER | 2 | Oct 14, 2020 | clinicaltrials |
| NCT00026780 | Eligibility Screening for a NCI Pediatric Oncology Branch Research Study | completed | — | 1,720 | National Cancer Institute (NCI)NIH | 1 | Oct 8, 2020 | clinicaltrials |
| NCT03032679 | Pain and Impact of Chronic Pain on Function After Total Knee Replacements | completed | — | 139 | Tata Memorial CentreOTHER | 1 | Oct 8, 2020 | clinicaltrials |
| NCT01987102 | Investigation of [6R] 5,10-methylenetetrahydrofolate (Arfolitixorin) as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX. | completed | Phase 1 / Phase 2 | 18 | Isofol Medical ABINDUSTRY | 4 | Sep 25, 2020 | clinicaltrials |
| NCT04461223 | Evaluation of Myocardial Injury After Anthracycline Chemotherapy in Osteosarcoma Patients Using CMR | unknown | — | 55 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jul 8, 2020 | clinicaltrials |
| NCT01331135 | Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors(Aflac ST0901) | completed | Phase 1 | 18 | Emory UniversityOTHER | 1 | May 29, 2020 | clinicaltrials |
| NCT02097238 | Eribulin Mesylate in Treating Patients With Recurrent or Refractory Osteosarcoma | completed | Phase 2 | 19 | National Cancer Institute (NCI)NIH | 2 | May 19, 2020 | clinicaltrials |
| NCT04351308 | Comparison of MAPI+Camrelizumab Versus API+Apatinib Versus MAPI in Patients With a Poor Response to Preoperative Chemotherapy for Newly Diagnosed High-grade Osteosarcoma(MAPAC) | unknown | Phase 2 | 60 | Peking University People's HospitalOTHER | 1 | May 19, 2020 | clinicaltrials |
| NCT01154816 | Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia | completed | Phase 2 | 118 | Children's Oncology GroupNETWORK | 2 | May 13, 2020 | clinicaltrials |
| NCT02223052 | Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies | completed | Phase 1 | 89 | CelgeneINDUSTRY | 1 | May 12, 2020 | clinicaltrials |
| NCT02390843 | Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors(AflacST1402) | completed | Phase 1 | 13 | Emory UniversityOTHER | 1 | Apr 3, 2020 | clinicaltrials |
| NCT04319874 | Phase II Clinical Trial Scheme of Ganoderma Lucidum Spore Powder for Postoperative Chemotherapy of Osteosarcoma | unknown | Phase 2 | 80 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Mar 30, 2020 | clinicaltrials |
| NCT04316091 | A Phase I Clinical Trial of Neoadjuvant Chemotherapy With/Without SPIONs/SMF for Patients With Osteosarcoma | unknown | Phase 1 | 60 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Mar 20, 2020 | clinicaltrials |
| NCT01848457 | Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy | completed | Phase 2 | 13 | Children's Hospital of PhiladelphiaOTHER | 1 | Mar 16, 2020 | clinicaltrials |
| NCT04294511 | Study of Camrelizumab in Combination With Neoadjuvant Chemotherapy in the Treatment of Osteosarcoma | unknown | Phase 2 | 75 | Sun Yat-sen UniversityOTHER | 1 | Mar 4, 2020 | clinicaltrials |
| NCT00752206 | A Placebo-Controlled Study of Saracatinib (AZD0530) in Patients With Recurrent Osteosarcoma Localized to the Lung | terminated | Phase 2 | 38 | Sarcoma Alliance for Research through CollaborationOTHER | 1 | Jan 18, 2020 | clinicaltrials |
| NCT01005043 | Therapy Trial to Determine the Safety and Efficacy of Heavy Ion Radiotherapy in Patients With Osteosarcoma | completed | Phase 1 / Phase 2 | 23 | University Hospital HeidelbergOTHER | 1 | Jan 10, 2020 | clinicaltrials |
| NCT01962103 | Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors | completed | Phase 1 / Phase 2 | 107 | CelgeneINDUSTRY | 7 | Dec 27, 2019 | clinicaltrials |
| NCT00428272 | HGS-ETR2 to Treat Children With Solid Tumors | terminated | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | Dec 17, 2019 | clinicaltrials |
| NCT02856048 | Co-treatment With GnRH Analogs on the Ovarian Reserve in Young Women Treated With Alkylating Agents for Cancer(PRESOV) | unknown | Phase 2 / Phase 3 | 11 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Dec 17, 2019 | clinicaltrials |
| NCT01886105 | Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma | terminated | Phase 2 | 4 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Oct 29, 2019 | clinicaltrials |
| NCT02441309 | A Eurosarc Study of Mifamurtide in Advanced Osteosarcoma (MEMOS)(MEMOS) | terminated | Phase 2 | 8 | University of OxfordOTHER | 5 | Sep 13, 2019 | clinicaltrials |
Data updated 22 days agoSource updated Oct 4, 2022source: clinicaltrials