Cancer Family
Osteogenic Neoplasm
CI-CAN-00000304Explore in graph →
Non-malignant101 active trials6 approved drugs8 evidence items
- NCIt
- C6603
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Cancer Family
CI-CAN-00000304Explore in graph →
Clinical trials
357 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05942456 | Soluble B7-H3 as a Biomarker for Osteosarcoma | unknown | — | 200 | Peking University People's HospitalOTHER | 1 | May 14, 2024 | clinicaltrials |
| NCT06412458 | IM83 Clinical Study of CAR-T Cell Therapy in Patients With Relapsed or Refractory Osteosarcoma | unknown | Phase 1 | 9 | Beijing Immunochina Medical Science & Technology Co., Ltd.INDUSTRY | 1 | May 14, 2024 | clinicaltrials |
| NCT05926492 | A Clinical Study of Surufatinib Combined With Chemotherapy as Neoadjuvant Treatment in Osteosarcoma | unknown | Phase 2 | 160 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Apr 17, 2024 | clinicaltrials |
| NCT05057130 | Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors | unknown | Phase 2 / Phase 3 | 50 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Apr 1, 2024 | clinicaltrials |
| NCT03242382 | Trial of Palbociclib in Second Line of Advanced Sarcomas With CDK4 Overexpression.(PalboSarc) | unknown | Phase 2 | 40 | Grupo Espanol de Investigacion en SarcomasOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT06217003 | Trilaciclib Combined With Chemotherapy for Perioperative Treatment of Osteosarcoma | unknown | Phase 2 | 20 | The First Affiliated Hospital of Xinxiang Medical CollegeOTHER | 1 | Jan 22, 2024 | clinicaltrials |
| NCT06171282 | A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Advanced Bone and Soft Tissue Tumors | unknown | Early Phase 1 | 9 | Shanghai Yunying Medical TechnologyINDUSTRY | 1 | Dec 14, 2023 | clinicaltrials |
| NCT06125171 | Tucidinostat Plus Apatinib for Advanced Osteosarcoma | unknown | Phase 2 | 46 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 0 | Nov 9, 2023 | clinicaltrials |
| NCT06117878 | Safety and Efficacy of NK510 to Treat Osteosarcoma and Soft Tissue Sarcoma | unknown | Early Phase 1 | 12 | Base Therapeutics (Shanghai) Co., Ltd.INDUSTRY | 1 | Nov 7, 2023 | clinicaltrials |
| NCT03742193 | Pulmonary Resectable Metastases of Osteosarcoma With Anti-angiogenics and CHemotherapy(PROACH) | unknown | Phase 2 | 43 | Ruijin HospitalOTHER | 1 | Nov 1, 2023 | clinicaltrials |
| NCT03108677 | Circulating Exosome RNA in Lung Metastases of Primary High-Grade Osteosarcoma | unknown | — | 90 | Ruijin HospitalOTHER | 1 | Oct 3, 2023 | clinicaltrials |
| NCT04735289 | Dietary Habits, Metabolome, Immune Profile and Microbiota in Patients With Bone Sarcoma(Metabol-Sarc) | unknown | — | 810 | Istituto Ortopedico RizzoliOTHER | 1 | Aug 4, 2023 | clinicaltrials |
| NCT05851456 | A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Bone and Soft Tissue Tumors | unknown | Early Phase 1 | 20 | Shanghai Yunying Medical TechnologyINDUSTRY | 1 | May 9, 2023 | clinicaltrials |
| NCT04867421 | Neutrophils in Bone Sarcomas(TANOs) | unknown | — | 25 | Université de Reims Champagne-ArdenneOTHER | 1 | May 25, 2022 | clinicaltrials |
| NCT02013336 | Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors | unknown | Phase 1 | 30 | South Plains Oncology ConsortiumNETWORK | 1 | Mar 31, 2022 | clinicaltrials |
| NCT05194605 | Predictive Models of Treatment Responses and Survival Outcomes in Patients With Osteosarcoma | unknown | — | 800 | West China HospitalOTHER | 1 | Jan 31, 2022 | clinicaltrials |
| NCT04945512 | Efficacy of Epidural Analgesia in Lower Extremity Osteosarcoma | unknown | N/A | 28 | Istanbul UniversityOTHER | 1 | Nov 9, 2021 | clinicaltrials |
| NCT03298971 | The Impact of Cancer on the Physical and Psychosocial Well-being Among Childhood Osteosarcoma Survivors | unknown | — | 240 | The University of Hong KongOTHER | 1 | Sep 8, 2021 | clinicaltrials |
| NCT04757064 | Efficacy of Exercise Program on Osteosarcoma Patients | unknown | N/A | 40 | Cairo UniversityOTHER | 0 | Aug 6, 2021 | clinicaltrials |
| NCT04886765 | A Study to Evaluate the Safety and Efficacy of ALMB-0168 in Patients With Osteosarcoma | unknown | Phase 1 / Phase 2 | 238 | AlaMab Therapeutics (Shanghai) Inc.INDUSTRY | 0 | May 14, 2021 | clinicaltrials |
| NCT04864821 | Clinical Study of CD276 Targeted Autologous Chimeric Antigen Receptor T Cell Infusion in Patients With CD276 Positive Advanced Solid Tumor | unknown | Early Phase 1 | 24 | PersonGen BioTherapeutics (Suzhou) Co., Ltd.INDUSTRY | 0 | May 6, 2021 | clinicaltrials |
| NCT04461223 | Evaluation of Myocardial Injury After Anthracycline Chemotherapy in Osteosarcoma Patients Using CMR | unknown | — | 55 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jul 8, 2020 | clinicaltrials |
| NCT04351308 | Comparison of MAPI+Camrelizumab Versus API+Apatinib Versus MAPI in Patients With a Poor Response to Preoperative Chemotherapy for Newly Diagnosed High-grade Osteosarcoma(MAPAC) | unknown | Phase 2 | 60 | Peking University People's HospitalOTHER | 1 | May 19, 2020 | clinicaltrials |
| NCT04319874 | Phase II Clinical Trial Scheme of Ganoderma Lucidum Spore Powder for Postoperative Chemotherapy of Osteosarcoma | unknown | Phase 2 | 80 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Mar 30, 2020 | clinicaltrials |
| NCT04316091 | A Phase I Clinical Trial of Neoadjuvant Chemotherapy With/Without SPIONs/SMF for Patients With Osteosarcoma | unknown | Phase 1 | 60 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 0 | Mar 20, 2020 | clinicaltrials |
| NCT04294511 | Study of Camrelizumab in Combination With Neoadjuvant Chemotherapy in the Treatment of Osteosarcoma | unknown | Phase 2 | 75 | Sun Yat-sen UniversityOTHER | 1 | Mar 4, 2020 | clinicaltrials |
| NCT02856048 | Co-treatment With GnRH Analogs on the Ovarian Reserve in Young Women Treated With Alkylating Agents for Cancer(PRESOV) | unknown | Phase 2 / Phase 3 | 11 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Dec 17, 2019 | clinicaltrials |
| NCT03605199 | Denosumab in Subjects With Giant Cell Rich Tumors of Bone | unknown | Phase 2 | 60 | Leiden University Medical CenterOTHER | 3 | Aug 26, 2019 | clinicaltrials |
| NCT03932058 | Proteomics Research of Osteosarcoma(PROS001) | unknown | — | 400 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | May 2, 2019 | clinicaltrials |
| NCT03676985 | A Clinical Study of PD-L1 Antibody ZKAB001(Drug Code) in Limited Stage of High-grade Osteosarcoma | unknown | Phase 1 / Phase 2 | 15 | Lee's Pharmaceutical LimitedINDUSTRY | 1 | Sep 26, 2018 | clinicaltrials |
| NCT01807468 | Haploidentical Stem Cell Transplantation and NK Cell Therapy in Patients With High-risk Solid Tumors | unknown | Phase 2 | 12 | Samsung Medical CenterOTHER | 1 | Sep 18, 2018 | clinicaltrials |
| NCT03360760 | Timing of Surgery in Nonmetastatic Osteosarcoma of the Pelvis and Sacrum | unknown | N/A | 100 | Peking University People's HospitalOTHER | 1 | Aug 28, 2018 | clinicaltrials |
| NCT03390946 | Feasibility Study of Interval Compressed Regimen Using Four-drugs for Osteosarcoma | unknown | Phase 2 | 23 | Byung-Kiu ParkOTHER_GOV | 1 | Jan 9, 2018 | clinicaltrials |
| NCT03362086 | The Osteosarcoma Biobank in Peking University People's Hospital | unknown | — | 180 | Peking University People's HospitalOTHER | 0 | Dec 5, 2017 | clinicaltrials |
| NCT03358628 | Patient-derived Xenograft (PDX) Modeling to Test Drug Response for High-grade Osteosarcoma | unknown | — | 20 | Peking University People's HospitalOTHER | 0 | Nov 30, 2017 | clinicaltrials |
| NCT03336554 | Epigenetic Biomarker for Osteosarcoma | unknown | — | 100 | Peking University People's HospitalOTHER | 1 | Nov 13, 2017 | clinicaltrials |
| NCT02982486 | A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma | unknown | Phase 2 | 60 | Assaf-Harofeh Medical CenterOTHER_GOV | 0 | Nov 1, 2017 | clinicaltrials |
| NCT03163381 | Apatinib Second Line Treatment for Advanced Osteosarcoma and Soft Tissue Sarcomas ,Openting ,Single Center, One-armed Clinical Study. | unknown | Phase 2 | 40 | Henan Cancer HospitalOTHER_GOV | 1 | May 23, 2017 | clinicaltrials |
| NCT03063983 | Clinical Trial Evaluating Metronomic Chemotherapy in Patients With Metastatic Osteosarcoma(GLATO2017) | unknown | Phase 2 | 158 | Grupo de Apoio ao Adolescente e a Crianca com CancerOTHER | 1 | Mar 13, 2017 | clinicaltrials |
| NCT01669369 | Clinical Trial of Lithium Carbonate Combined With Neo-adjuvant Chemotherapy to Treat Osteosarcoma(Li2CO3) | unknown | Phase 4 | 400 | Sun Yat-sen UniversityOTHER | 1 | Nov 1, 2016 | clinicaltrials |
| NCT01758666 | A Clinical Research on the Relation of Blood Drug Concentration and Calcium Folinate Rescued in High-dose MTX Therapy | unknown | N/A | 40 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Dec 22, 2015 | clinicaltrials |
| NCT02309242 | Long Term Neurotoxic Effects of Chemotherapy in Survivors of Bone and Soft Tissue Sarcomas. A Retrospective Study | unknown | N/A | 60 | Universitaire Ziekenhuizen KU LeuvenOTHER | 1 | Aug 21, 2015 | clinicaltrials |
| NCT02302651 | Non-invasive Focal Therapy for Osteoid Osteoma | unknown | Phase 2 / Phase 3 | 60 | University of Roma La SapienzaOTHER | 1 | Nov 27, 2014 | clinicaltrials |
| NCT01002092 | A Study of Endostar Combined With Chemotherapy for Treatment of Osteosarcoma | unknown | Phase 2 | 160 | Shandong Simcere-Medgenn Bio-pharmaceutical Co., LtdINDUSTRY | 1 | Sep 3, 2014 | clinicaltrials |
| NCT01216826 | Phase II Study of Everolimus in Children and Adolescents With Refractory or Relapsed Osteosarcoma | unknown | Phase 2 | 20 | Sidnei EpelmanOTHER | 1 | Aug 7, 2013 | clinicaltrials |
| NCT01780779 | Osteosarcoma and Ewing Sarcoma Treatment Response Assessment With Functional MRI Imaging in Children and Young Adults(FUBEO) | unknown | — | 25 | Universitaire Ziekenhuizen KU LeuvenOTHER | 1 | Jan 31, 2013 | clinicaltrials |
| NCT00689195 | Pilot Study of Curcumin Formulation and Ashwagandha Extract in Advanced Osteosarcoma(OSCAT) | unknown | Phase 1 / Phase 2 | 24 | Tata Memorial HospitalOTHER_GOV | 1 | Jun 23, 2011 | clinicaltrials |
| NCT00691236 | Evaluation of Zoledronic Acid as a Single Agent or as an Adjuvant to Chemotherapy in High Grade Osteosarcoma(ZOL) | unknown | Phase 2 / Phase 3 | 60 | Tata Memorial HospitalOTHER_GOV | 1 | Jun 23, 2011 | clinicaltrials |
| NCT00180947 | Study of Vinorelbine and Cyclofosfamide Among Patients With Refractory Tumours or in Relapse | unknown | Phase 2 | 210 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | Sep 8, 2006 | clinicaltrials |
Data updated 22 days agoSource updated May 14, 2024source: clinicaltrials