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Genomics
15 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
903 cases with simple somatic mutation data · 942 cases total · 2026-01-16 · mapped to Acute Myeloid Leukemia EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | FLT3 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 278 |
| 903 |
| 30.8% |
| cbioportal |
| 2 | NPM1 | Ssm | 233 | 903 | 25.8% | cbioportal |
| 3 | DNMT3A | Ssm | 197 | 903 | 21.8% | cbioportal |
| 4 | NRAS | Ssm | 119 | 903 | 13.2% | cbioportal |
| 5 | TET2 | Ssm | 118 | 903 | 13.1% | cbioportal |
| 6 | IDH2 | Ssm | 111 | 903 | 12.3% | cbioportal |
| 7 | SRSF2 | Ssm | 109 | 903 | 12.1% | cbioportal |
| 8 | RUNX1 | Ssm | 108 | 903 | 12% | cbioportal |
| 9 | ASXL1 | Ssm | 93 | 903 | 10.3% | cbioportal |
| 10 | TP53 | Ssm | 82 | 903 | 9.1% | cbioportal |
| 11 | WT1 | Ssm | 72 | 903 | 8% | cbioportal |
| 12 | IDH1 | Ssm | 71 | 903 | 7.9% | cbioportal |
| 13 | STAG2 | Ssm | 60 | 903 | 6.6% | cbioportal |
| 14 | SF3B1 | Ssm | 49 | 903 | 5.4% | cbioportal |
| 15 | BCOR | Ssm | 48 | 903 | 5.3% | cbioportal |
| 16 | CEBPA | Ssm | 45 | 903 | 5% | cbioportal |
| 17 | U2AF1 | Ssm | 45 | 903 | 5% | cbioportal |
| 18 | PTPN11 | Ssm | 44 | 903 | 4.9% | cbioportal |
| 19 | KRAS | Ssm | 43 | 903 | 4.8% | cbioportal |
| 20 | GATA2 | Ssm | 37 | 903 | 4.1% | cbioportal |
| 21 | JAK2 | Ssm | 36 | 903 | 4% | cbioportal |
| 22 | PDS5B | Ssm | 32 | 903 | 3.5% | cbioportal |
| 23 | EZH2 | Ssm | 28 | 903 | 3.1% | cbioportal |
| 24 | PHF6 | Ssm | 26 | 903 | 2.9% | cbioportal |
| 25 | NF1 | Ssm | 25 | 903 | 2.8% | cbioportal |
| 26 | RAD21 | Ssm | 20 | 903 | 2.2% | cbioportal |
| 27 | CBL | Ssm | 19 | 903 | 2.1% | cbioportal |
| 28 | BCORL1 | Ssm | 18 | 903 | 2% | cbioportal |
| 29 | KIT | Ssm | 18 | 903 | 2% | cbioportal |
| 30 | ZRSR2 | Ssm | 14 | 903 | 1.6% | cbioportal |
Data updated 21 days agoSource updated 2026-01-16