Hematologic Malignancy
Mature B-Cell Non-Hodgkin Lymphoma
CI-CAN-00003259Explore in graph →
Hematologic792 active trials17 approved drugs43 evidence items
- NCIt
- C7056
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Hematologic Malignancy
CI-CAN-00003259Explore in graph →
Genomics
18 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
160 cases with simple somatic mutation data · 160 cases total · 2026-01-07 · mapped to Small Lymphocytic Lymphoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | SF3B1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 23 |
| 160 |
| 14.4% |
| cbioportal |
| 2 | TP53 | Ssm | 19 | 160 | 11.9% | cbioportal |
| 3 | NOTCH1 | Ssm | 15 | 160 | 9.4% | cbioportal |
| 4 | MYD88 | Ssm | 12 | 160 | 7.5% | cbioportal |
| 5 | ATM | Ssm | 9 | 160 | 5.6% | cbioportal |
| 6 | CHD2 | Ssm | 6 | 160 | 3.8% | cbioportal |
| 7 | MUC16 | Ssm | 6 | 160 | 3.8% | cbioportal |
| 8 | FAT3 | Ssm | 5 | 160 | 3.1% | cbioportal |
| 11 | TTN | Ssm | 5 | 160 | 3.1% | cbioportal |
| 10 | POT1 | Ssm | 5 | 160 | 3.1% | cbioportal |
| 9 | H1-4 | Ssm | 5 | 160 | 3.1% | cbioportal |
| 12 | XPO1 | Ssm | 5 | 160 | 3.1% | cbioportal |
| 21 | SLIT3 | Ssm | 4 | 160 | 2.5% | cbioportal |
| 18 | RIPK1 | Ssm | 4 | 160 | 2.5% | cbioportal |
| 14 | FAT4 | Ssm | 4 | 160 | 2.5% | cbioportal |
| 19 | SAMHD1 | Ssm | 4 | 160 | 2.5% | cbioportal |
| 20 | SCN2A | Ssm | 4 | 160 | 2.5% | cbioportal |
| 16 | NRAS | Ssm | 4 | 160 | 2.5% | cbioportal |
| 13 | CSMD1 | Ssm | 4 | 160 | 2.5% | cbioportal |
| 22 | SRCAP | Ssm | 4 | 160 | 2.5% | cbioportal |
| 15 | NAV2 | Ssm | 4 | 160 | 2.5% | cbioportal |
| 23 | WDR72 | Ssm | 4 | 160 | 2.5% | cbioportal |
| 17 | PCLO | Ssm | 4 | 160 | 2.5% | cbioportal |
| 52 | PLXNA2 | Ssm | 3 | 160 | 1.9% | cbioportal |
| 38 | FBXW7 | Ssm | 3 | 160 | 1.9% | cbioportal |
| 37 | DSG4 | Ssm | 3 | 160 | 1.9% | cbioportal |
| 33 | CUBN | Ssm | 3 | 160 | 1.9% | cbioportal |
| 39 | GABRA2 | Ssm | 3 | 160 | 1.9% | cbioportal |
| 30 | CECR2 | Ssm | 3 | 160 | 1.9% | cbioportal |
| 26 | BCR | Ssm | 3 | 160 | 1.9% | cbioportal |
Data updated 22 days agoSource updated 2026-01-07