Cancer
Malignant Rectal Neoplasm
CI-CAN-00008012Explore in graph →
Top-level388 active trials1 approved drugs5 evidence items
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Cancer
CI-CAN-00008012Explore in graph →
Clinical trials
1,551 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (153)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01923987 | Short Course Radiotherapy Followed Intensive Chemotherapy With Delayed Surgery for Rectal Cancer With Synchronous Distant Metastasis | unknown | Phase 2 | 39 | Korea Cancer Center HospitalOTHER | 1 | Sep 20, 2019 | clinicaltrials |
| NCT01047969 | Avoiding Surgery in Rectal Cancer After Pre-Operative Therapy | unknown | Phase 2 | 99 | Royal Marsden NHS Foundation TrustOTHER | 1 | Jun 13, 2019 | clinicaltrials |
| NCT02648386 | Stem Cell Therapy Combined With NeuroRegen Scaffold™ in Patients With Erectile Dysfunction After Rectal Cancer Surgery | unknown | Phase 1 / Phase 2 | 34 | Chinese Academy of SciencesOTHER_GOV | 1 | Jan 25, 2019 | clinicaltrials |
| NCT03040180 | Endoscopic Assisted Electrochemotherapy in Addition to Neoadjuvant Treatment of Locally Advanced Rectal Cancer(nECT) | unknown | Phase 2 | 40 | Zealand University HospitalOTHER | 1 | Jan 25, 2019 | clinicaltrials |
| NCT03702985 | Radiation-protection Effect of Amifostine in Locally Advanced Rectal Cancer | unknown | Phase 2 | 160 | Fudan UniversityOTHER | 1 | Jan 23, 2019 | clinicaltrials |
| NCT01037049 | Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks | unknown | Phase 2 | 237 | Royal Marsden NHS Foundation TrustOTHER | 4 | Sep 17, 2018 | clinicaltrials |
| NCT02919878 | Neo-adjuvant Chemoradiotherapy Using Infusional Gemcitabine Followed by Surgery for Locally Advanced Rectal Cancer | unknown | Phase 2 | 25 | King Faisal Specialist Hospital & Research CenterOTHER | 1 | Aug 13, 2018 | clinicaltrials |
| NCT03607643 | A Study of the Efficacy of Cannabidiol in Patients With Multiple Myeloma, Glioblastoma Multiforme, and GI Malignancies | unknown | Phase 1 / Phase 2 | 160 | Leaf Vertical Inc.INDUSTRY | 1 | Jul 31, 2018 | clinicaltrials |
| NCT03561142 | Organ Preservation in Locally Advanced Rectal Cancer by Radiochemotherapy Followed by Consolidation Chemotherapy.(CAO/ARO/AIO-16) | unknown | Phase 2 | 94 | University Hospital TuebingenOTHER | 1 | Jun 19, 2018 | clinicaltrials |
| NCT02942563 | Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer | unknown | Phase 2 | 100 | RenJi HospitalOTHER | 1 | Jan 3, 2018 | clinicaltrials |
| NCT01431599 | Short-course Preoperative Chemoradiotherapy for Rectal Cancer(KROG 11-02) | unknown | Phase 2 | 80 | Jong Hoon LeeOTHER | 1 | Oct 10, 2017 | clinicaltrials |
| NCT03280407 | NEOadjuvant Chemotherapy Only Compared With Standard Treatment for Locally Advanced Rectal Cancer(NEOLAR) | unknown | Phase 2 | 124 | Zealand University HospitalOTHER | 1 | Sep 28, 2017 | clinicaltrials |
| NCT01716949 | Neoadjuvant Chemoradiation With 5-FU(or Capecitabine) and Oxaliplatin Combined With Hyperthermia in Rectal Cancer(HyRec) | unknown | Phase 1 / Phase 2 | 59 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Aug 11, 2017 | clinicaltrials |
| NCT03242187 | Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer(MansTaTME) | unknown | Phase 2 / Phase 3 | 30 | Mansoura UniversityOTHER | 1 | Aug 8, 2017 | clinicaltrials |
| NCT02941562 | A Prospective Phase II Randomized Clinical Trial of Preoperative Chemotherapy Combined With Short-course Radiotherapy Versus Conventional Neo-adjuvant Therapy for Locally Advanced Rectal Cancer Implemented by MDT | unknown | Phase 2 | 150 | Xinhua Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 0 | Oct 24, 2016 | clinicaltrials |
| NCT02905968 | Transanual Tube Placement in Low Anterior Resection (LAR) for Rectal Cancer | unknown | Phase 2 / Phase 3 | 520 | Fudan UniversityOTHER | 1 | Sep 19, 2016 | clinicaltrials |
| NCT02830633 | Trial to Evaluate Laparoscopy-assisted Nerve-preserved Total Mesorectal Excision (LNTME) Versus Open TME for Rectal Cancer | unknown | Phase 2 | 80 | Anhui Medical UniversityOTHER | 0 | Jul 13, 2016 | clinicaltrials |
| NCT02603302 | Radiation Dose Escalation in Locally Advanced Rectal Cancer(RaDE) | unknown | Phase 2 | 48 | University of BrasiliaOTHER | 1 | Jun 14, 2016 | clinicaltrials |
| NCT01257360 | Panitumumab in Combination With Radiotherapy in Patients With Locally Advanced RAS Wildtype Rectal Cancer (Clinical Stages II and III)(NEO-RIT) | unknown | Phase 2 | 59 | WiSP Wissenschaftlicher Service Pharma GmbHOTHER | 1 | Jan 13, 2016 | clinicaltrials |
| NCT02510378 | Short Course Radiotherapy Combined With Chemotherapy in Stage IV Rectal Cancer With Resectable Liver Metastases | unknown | Phase 2 | 47 | Chinese Academy of Medical SciencesOTHER | 1 | Jul 29, 2015 | clinicaltrials |
| NCT02490709 | Local Excision of Clinical T3 Rectal Adenocarcinoma Showing Major Response(ycT0-1) After Neoadjuvant Chemoradiotherapy | unknown | Phase 2 | 86 | National Cancer Center, KoreaOTHER_GOV | 1 | Jul 7, 2015 | clinicaltrials |
| NCT02488707 | Minimally Invasive Sphincter Sparing Total Mesorectal Excision for Ultra-low Rectal Cancer After Initial Chemo-radiotherapy (MISS-TRICR).(MISS-TRICR) | unknown | Phase 2 | 250 | Mansoura UniversityOTHER | 1 | Jul 2, 2015 | clinicaltrials |
| NCT01818973 | Preoporative Bevacizumab, Radiation Therapy, and XELOX Chemotherapy for Locally Advanced Nonmetastatic Rectal Cancer | unknown | Phase 2 | 45 | Sun Yat-sen UniversityOTHER | 1 | Jun 8, 2015 | clinicaltrials |
| NCT01211210 | Neoadjuvant FOLFOX6 Chemotherapy With or Without Radiation in Rectal Cancer(FOWARC) | unknown | Phase 2 / Phase 3 | 495 | Sun Yat-sen UniversityOTHER | 1 | May 22, 2015 | clinicaltrials |
| NCT02195141 | Trial of Using SIB-IMRT in Preoperative Radiotherapy for Locally Advanced Rectum Cancer | unknown | Phase 2 | 104 | Chinese Academy of Medical SciencesOTHER | 1 | Feb 4, 2015 | clinicaltrials |
| NCT02288078 | Oral Steroids for Regorafenib-induced Fatigue/Malaise in Unresectable mCRC (KSCC1402/HGCSG1402) | unknown | Phase 2 | 74 | Clinical Research Support Center KyushOTHER | 1 | Nov 13, 2014 | clinicaltrials |
| NCT02280070 | RP II Study of SOX vs mFOLFOX6 in Patients With Resectable Rectal Cancer (KSCC1301). | unknown | Phase 2 | 110 | Clinical Research Support Center KyushOTHER | 1 | Oct 31, 2014 | clinicaltrials |
| NCT02268006 | IMRT-SIB and Capecitabine in Preoperative Rectal Cancer Treatment(BISER) | unknown | Phase 2 | 50 | Institute of Oncology LjubljanaOTHER | 1 | Oct 20, 2014 | clinicaltrials |
| NCT02177084 | Percutaneous Tibial Nerve Stimulation in the Treatment of Anterior Resection Syndrome After Rectal Cancer Surgery | unknown | Phase 2 | 12 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 1 | Jun 27, 2014 | clinicaltrials |
| NCT00795301 | A Study of Radiotherapy in Rectal Cancer Using Oxaliplatin, Capecitabine With or Without Cetuximab | unknown | Phase 2 | 74 | National University Hospital, SingaporeOTHER | 1 | Jan 14, 2014 | clinicaltrials |
| NCT02022852 | Neoadjuvant Sequential Therapy in Locally Advanced Mid/Low Rectal Cancer | unknown | Phase 2 | 80 | Harbin Medical UniversityOTHER | 1 | Dec 30, 2013 | clinicaltrials |
| NCT01586117 | A Phase II Study of Amifostine for the Prevention of Acute Radiation-Induced Rectal Toxicity | unknown | Phase 2 | 40 | Chinese Academy of Medical SciencesOTHER | 1 | Aug 15, 2013 | clinicaltrials |
| NCT01899118 | Nimotuzumab in Combination With Chemoradiation in Patients With Locally Advanced Rectal Cancer | unknown | Phase 2 | 50 | Zhejiang Cancer HospitalOTHER | 1 | Jul 15, 2013 | clinicaltrials |
| NCT01227239 | Preoperative S-1/OHP With Radiation Therapy for Low-lying Rectal Carcinoma in Neo-adjuvant Setting | unknown | Phase 1 / Phase 2 | 45 | Japan Clinical Cancer Research OrganizationOTHER | 1 | Nov 27, 2012 | clinicaltrials |
| NCT01237665 | IXO (Irinotecan, Xeloda, Oxaliplatin) in Rectal Cancer(IXOr) | unknown | Phase 2 | 15 | Ottawa Hospital Research InstituteOTHER | 1 | Oct 15, 2012 | clinicaltrials |
| NCT00689702 | Cetuximab (Erbitux®), Capecitabine and Radiotherapy in Neoadjuvant Treatment of Patients With Rectal Cancer(XERT) | unknown | Phase 2 | 43 | Institute of Oncology LjubljanaOTHER | 1 | Mar 26, 2012 | clinicaltrials |
| NCT00842686 | Preoperative Radiotherapy With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer: CRAB Phase II Study(CRAB) | unknown | Phase 2 | 60 | Institute of Oncology LjubljanaOTHER | 1 | Mar 26, 2012 | clinicaltrials |
| NCT01064999 | A Trial of High Intensity Versus Low Intensity Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer | unknown | Phase 2 / Phase 3 | 240 | Fudan UniversityOTHER | 1 | Mar 14, 2012 | clinicaltrials |
| NCT00122291 | A Study of Preoperative Radiation Therapy and Capecitabine in Locally Advanced Rectal Cancer | unknown | Phase 2 | 66 | Alberta Health servicesOTHER | 1 | Jan 19, 2012 | clinicaltrials |
| NCT01489332 | Induction Chemotherapy,Radiochemotherapy, Consolidation Chemotherapy in Preoperative Treatment of Rectal Cancer | unknown | Phase 2 | 60 | Institute of Oncology LjubljanaOTHER | 1 | Dec 9, 2011 | clinicaltrials |
| NCT00635466 | Phase II Trial to Evaluate Laparoscopic Surgery for Stage 0/I Rectal Carcinoma(Lap RC) | unknown | Phase 2 | 495 | Japan Society of Laparoscopic Colorectal SurgeryNETWORK | 1 | Jun 16, 2011 | clinicaltrials |
| NCT01340508 | Preoperative Concurrent Chemotherapy and Intensity Modulated Radiotherapy (IMRT) in Locally Advanced Rectal Cancer | unknown | Phase 2 | 63 | National University Hospital, SingaporeOTHER | 1 | Apr 22, 2011 | clinicaltrials |
| NCT01157806 | Palliative Radiochemotherapy Against Palliative Surgery in Stage IV Rectal Cancer With Unresectable Metastases | unknown | Phase 2 | 20 | Maria Sklodowska-Curie National Research Institute of OncologyOTHER | 1 | Feb 16, 2011 | clinicaltrials |
| NCT01142713 | The Impact of Patient Positioning and Use of Belly Board on Small Bowel and Urinary Bladder Volume Irradiated in Patients Receiving Radiotherapy for Rectal Cancer: A Prospective Phase II Study | unknown | Phase 2 | 30 | Tel-Aviv Sourasky Medical CenterOTHER_GOV | 1 | Jun 11, 2010 | clinicaltrials |
| NCT00964457 | Treatment of Patients With Advanced Rectum Cancer With Capecitabine and Oxaliplatin Before, Under and After Radiation and With Adding Cetuximab to K-RAS Wild-type Patients | unknown | Phase 2 | 60 | Copenhagen University Hospital at HerlevOTHER | 1 | Aug 25, 2009 | clinicaltrials |
| NCT00254683 | Use of Positron Emission Tomography/Computed Tomography (PET/CT) to Assess Tumor Response to Neoadjuvant Treatment for Distal Rectal Cancer | unknown | Phase 2 | 100 | University of Sao PauloOTHER | 1 | Apr 14, 2009 | clinicaltrials |
| NCT00808379 | Concurrent Chemo-Radiotherapy Versus Radiotherapy With Boost in Locally Advanced Unresectable Rectal Cancers | unknown | Phase 2 | 90 | Tata Memorial HospitalOTHER_GOV | 1 | Dec 15, 2008 | clinicaltrials |
| NCT00557713 | XELOX+Bevacizumab Followed by Capecitabine+Bevacizumab+Radiotherapy as Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma | unknown | Phase 2 | 44 | Associacio catalana per a la recerca oncologica i les seves implicacions sanitaries i socialsOTHER | 1 | Nov 14, 2007 | clinicaltrials |
Data updated 22 days agoSource updated Sep 20, 2019source: clinicaltrials