Clinical trial · Interventional
Minimally Invasive Sphincter Sparing Total Mesorectal Excision for Ultra-low Rectal Cancer After Initial Chemo-radiotherapy (MISS-TRICR).
Outcomes of Transanal Minimally Invasive TME Versus Laparoscopic Intersphincteric Resection Techniques for Rectal Cancer After Initial Neoadjuvant Chemo-radiotherapy: Double Blinded Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A prospective study is planned for management of low rectal cancer with the aim of sphincter preservation and improving the oncological outcome of the patients, through comparing of both approaches minimally invasive techniques including transanal total mesorectal excision and laparoscopic intersphincteric resection.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| laparoscopic intersphincteric resection (LISR group) | Procedure | — | UNRESOLVED |
| Transanal minimally invasive Total mesorectal excision (TAMIS group) | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- LISR group
- description
- Cases which undergo rectal resection with laparoscopic intersphincteric resection.
- interventionNames
- Procedure: laparoscopic intersphincteric resection (LISR group)
- type
- ACTIVE_COMPARATOR
- label
- TAMIS Group
- description
- Cases with rectal cancer which undergo Transanal minimally invasive Total mesorectal excision.
- interventionNames
- Procedure: Transanal minimally invasive Total mesorectal excision (TAMIS group)
Primary outcomes (2)
- measure
- Percent of Intraoperative and postoperative morbidity within 30 days starting from the time of the operation
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient with low rectal cancer below 5 cm from the anal verge * Fit (Medically and surgically) for laparoscopy. Exclusion Criteria: * Patient with massive abdominal adhesions * Unfit for laparoscopy * Unwilling to share in the study
References
Publications (0)
Data not yet available