Malignant Mixed Neoplasm

Microarray-based comparative genomic hybridization (aCGH) analysis was carried out on 58 Wilms’ tumor samples. 38 tumors were untreated primary and 20 were recurrent. An increase in copy number change… (full text at CIViC)

PMID 17103382 · Natrajan et al., 2007 · Open in CIViC

77 tumors from Wilms Tumor patients were tested with Illumina BeadChip arrays and genomic profiles were tested for association with relapse and other clinicopathological variables. Copy number gain at… (full text at CIViC)

PMID 22407497 · Perotti et al., 2012 · Open in CIViC

Anaplastic histology (AH) in Wilm's Tumor is characterized by abnormal mitoses, and associated with poor prognosis in comparison to favorable histology (FH). Array CGH was used on 53 AH samples, and a… (full text at CIViC)

PMID 21882282 · Williams et al., 2011 · Open in CIViC

This variant was detected in one patient belonging to the Kenyan Wilms Tumor patient cohort from sub-Saharan Africa.

PMID 26274016 · Lovvorn et al., 2015 · Open in CIViC

Elevated levels of CCNE1 mRNA has been shown to be correlated with advanced stage gastric carcinoma.

PMID 10224221 · Donnellan et al., 1999 · Open in CIViC

Elevated levels of CCNE1 mRNA has been shown to be correlated with increased depth of tumor invasion in gastic carcinoma.

PMID 10224221 · Donnellan et al., 1999 · Open in CIViC

153 primary Wilms tumor samples from 150 patients were analyzed for mutations in the WT1 and CTNNB1 genes. Ten WT samples had the S45F, and 9 of them also had WT1 mutation. This study concluded a high… (full text at CIViC)

PMID 11103785 · Maiti et al., 2000 · Open in CIViC

This study analysed all five loci (WT1, CTNNB1, WTX, TP53 and the imprinted 11p15 region) in 120 Wilms tumors, and identify CTNNB1 mutation in 15% samples. Data on the 5 loci stratify Wilms tumors int… (full text at CIViC)

PMID 22470196 · Scott et al., 2012 · Open in CIViC

The HCC-366 lung adenosquamous carcinoma cell line, containing the DDR2 L239R mutation was shown to be sensitive (IC50 140nm) to dasatinib in-vitro. The authors were unable to establish tumors using t… (full text at CIViC)

PMID 22328973 · Hammerman et al., 2011 · Open in CIViC

A higher relapse rate was observed in patients that have both DROSHA E518K and SIX Q177R muations.

PMID 25670082 · Walz et al., 2015 · Open in CIViC

Human HER2 with YVMA insertion was put under a clara cell specific, rtTA promoter system inducible via doxycycline. Induction of mutant HER2 in these mice drove rapid development of adenosquamous lung… (full text at CIViC)

PMID 19122144 · Perera et al., 2009 · Open in CIViC

A 33-year old male patient (non-smoker) was diagnosed with Stage IVB adenosquamous lung carcinoma. Various treatment strategies were tried but all had progressive disease quickly after treatment. Next… (full text at CIViC)

PMID 33854337 · Jiao et al., 2021 · Open in CIViC

40 diffuse anaplasia in Wilms tumours (DAWT) samples were tested using copy number (n = 32) and gene expression (n = 36) arrays. 22 had TP53 mutations and 20 of these also had 17p loss. An increased r… (full text at CIViC)

PMID 25313908 · Maschietto et al., 2014 · Open in CIViC

44 archival FFPE samples from confirmed cases of Wilms tumor with mean age 3 years 2 months, and taken from the most histologically aggressive parts of each tumor, were stained with p53 monoclonal ant… (full text at CIViC)

PMID 21525573 · Jadali et al., 2011 · Open in CIViC