AMER1 R358X

CI-VAR-00003836Explore in graph →CIViC 2276

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Wilms Tumor1
AMER1 R358X	(diagnostic)	Diagnostic	B	Supports Positive	3	rejected	EID6079 This variant was detected in one patient belonging to the Kenyan Wilms Tumor patient cohort from sub-Saharan Africa. PMID 26274016 · Lovvorn et al., 2015 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.