Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06184867 | Choices About Genetic Testing And Learning Your Risk With Smart Technology(CATALYST) | completed | N/A | 50 | Rutgers, The State University of New JerseyOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT06608537 | A Clinical Study Based on FAPI-PET/CT Technology to Predict Pathological Complete Response After Neoadjuvant Chemoradiotherapy for MSS Rectal Cancer | completed | Phase 2 | 52 | Sun Yat-sen UniversityOTHER | 1 | Mar 4, 2026 |
| clinicaltrials |
| NCT02738359 | Efficacy of Colonoscopy, Colon Capsule and Fecal Immunological Test for Colorectal Cancer Screening(FAMCAP) | completed | — | 84 | Hôpital Edouard HerriotOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT03510858 | Randomized Controlled Trial on Colorectal Cancer Screening Among Quality Circles of Primary Care Physicians | completed | N/A | 44 | University of BernOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT03640208 | Educate, Assess Risk and Overcoming Barriers to Colorectal Screening Among African Americans | completed | N/A | 163 | Case Comprehensive Cancer CenterOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT03828799 | Safety, Tolerability and Efficacy of Regorafenib in Combination With FOLFIRINOX in Patients With Colorectal Cancer(FOLFIRINOX-R) | completed | Phase 1 / Phase 2 | 13 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT04761185 | Raltitrexed in HIPEC | completed | Phase 1 | 30 | Fudan UniversityOTHER | 1 | Feb 25, 2026 | clinicaltrials |
| NCT05424068 | Rehabilitation for People With Advanced Cancer | completed | N/A | 111 | University Health Network, TorontoOTHER | 1 | Feb 25, 2026 | clinicaltrials |
| NCT04426669 | A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering | completed | Phase 1 / Phase 2 | 23 | Intima Bioscience, Inc.INDUSTRY | 1 | Feb 23, 2026 | clinicaltrials |
| NCT07428239 | Pilot Study of Individualized Comprehensive Rehabilitation in Patients With Colorectal Cancer | completed | N/A | 150 | Institute of Oncology LjubljanaOTHER | 1 | Feb 23, 2026 | clinicaltrials |
| NCT01105169 | Precision-Based Magnesium Trial | completed | N/A | 250 | Vanderbilt University Medical CenterOTHER | 1 | Feb 20, 2026 | clinicaltrials |
| NCT07184047 | Frailty Scales for Predicting Chemotherapy Toxicity in Older Adults With Gastrointestinal Cancers(TOX-FRAIL) | completed | — | 72 | Ankara Etlik City HospitalOTHER_GOV | 1 | Feb 20, 2026 | clinicaltrials |
| NCT07423130 | Indocyanine Green Fluorescence Angiography in Laparoscopic Sigmoid and Rectal Cancer Surgery | completed | — | 115 | Jagiellonian UniversityOTHER | 1 | Feb 20, 2026 | clinicaltrials |
| NCT01858025 | Concurrent Chemoradiation + 5-FU + Mitomycin-C in Anal Carcinoma | completed | Early Phase 1 | 25 | Massachusetts General HospitalOTHER | 1 | Feb 18, 2026 | clinicaltrials |
| NCT05116085 | Efficacy and Safety of Tislelizumab (BGB-A317) as Neo-Adjuvant Treatment in Participants With Colorectal Cancer | completed | Phase 2 | 33 | BeiGeneINDUSTRY | 1 | Feb 13, 2026 | clinicaltrials |
| NCT05702684 | Personalised Cancer Care and Support: Identifying What Good Looks Like | completed | — | 76 | King's College LondonOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT06475664 | Colorectal Cancer Legal and Administrative Burden Support: A Pilot Clinical Trial | completed | Early Phase 1 | 20 | University of MinnesotaOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT05383976 | Improving Colorectal Cancer Screening in Racially Diverse Zip Codes Using Navigation and Machine Learning (PCSNaP)(PCSNaP) | completed | — | 385 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Feb 11, 2026 | clinicaltrials |
| NCT07398716 | Intraoperative Assessment of Distal Resection Margins Using Frozen Section in Mid and Low Rectal Cancer Surgery | completed | N/A | 99 | Bakirkoy Dr. Sadi Konuk Research and Training HospitalOTHER_GOV | 1 | Feb 11, 2026 | clinicaltrials |
| NCT00628368 | Biological Factors in Predicting Response to Treatment in Patients With Esophageal Cancer or Rectal Cancer | completed | N/A | 160 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT03365882 | S1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery | completed | Phase 2 | 240 | SWOG Cancer Research NetworkNETWORK | 2 | Feb 10, 2026 | clinicaltrials |
| NCT04109924 | TAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO Study | completed | Phase 2 | 42 | Roswell Park Cancer InstituteOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT05036109 | DAILY: Vitamin D, Aspirin, ExercIse, Low Saturated Fat Foods StudY in Colorectal Cancer Patients With Minimal Residual Disease | completed | N/A | 16 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT05648240 | Proof-of-concept Study of Blood Markers of Tumor Dissemination in Patients With Versus Without Intestinal Polyps(EARDIS) | completed | — | 120 | Centre Hospitalier Universitaire de NīmesOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT07391163 | Protective Effect of N-acetylcysteine on Oxaliplatin-Induced Neuropathy in Colorectal Cancer | completed | N/A | 46 | Tanta UniversityOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT03712943 | Regorafenib and Nivolumab in Mismatch Repair (MMR) Refractory Colorectal Cancer | completed | Phase 1 | 52 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Feb 9, 2026 | clinicaltrials |
| NCT05421702 | Comparison Between Results of 2 Laparoscopic Surgical Procedures in Operable Colon Cancer Cases in Upper Egypt | completed | N/A | 150 | Sohag UniversityOTHER | 1 | Feb 9, 2026 | clinicaltrials |
| NCT02956876 | Equivalence of Monitoring by a Nurse Practitioner for Patients With Digestive Cancer(INCISIVE) | completed | Phase 3 | 207 | University Hospital, RouenOTHER | 1 | Feb 6, 2026 | clinicaltrials |
| NCT03693807 | A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma | completed | Phase 2 | 35 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 6, 2026 | clinicaltrials |
| NCT04513223 | A Phase 1 Study of SHR-A1811 in Patients With Selected HER2 Expressing Tumors | completed | Phase 1 | 101 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Feb 6, 2026 | clinicaltrials |
| NCT05520840 | Evaluation of Peripheral Blood Protein Biomarkers for Colorectal Cancer Screening(COLODIAG) | completed | N/A | 350 | University Hospital, RouenOTHER | 1 | Feb 6, 2026 | clinicaltrials |
| NCT05536713 | Understanding Patient Preference on Colorectal Cancer Screening Options(U-Screen) | completed | — | 297 | Milton S. Hershey Medical CenterOTHER | 1 | Feb 6, 2026 | clinicaltrials |
| NCT00208260 | Intensified Chemotherapy in CRC After Resection of Liver Metastases | completed | Phase 2 / Phase 3 | 124 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT00556413 | Cetuximab and Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer | completed | Phase 2 | 42 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT03707574 | Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study | completed | — | 64 | National Cancer Institute (NCI)NIH | 2 | Feb 4, 2026 | clinicaltrials |
| NCT05102500 | Second Opinions in Oncology | completed | — | 236 | University of Colorado, DenverOTHER | 1 | Feb 3, 2026 | clinicaltrials |
| NCT04414306 | Screen to Save 2: Rural Cancer Screening Educational Intervention | completed | N/A | 205 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Feb 2, 2026 | clinicaltrials |
| NCT06241703 | Effect of ICCAUT Strategy on Postoperative Urinary Dysfunction After Radical Rectal Cancer Surgery(ICCAUT-1) | completed | N/A | 400 | The First Hospital of Jilin UniversityOTHER | 1 | Jan 30, 2026 | clinicaltrials |
| NCT02938481 | International Prospective Observational Cohort Study for Optimal Bowel Resection Extent and Central Radicality for Colon Cancer(T-REX) | completed | — | 3,647 | Translational Research Center for Medical Innovation, Kobe, Hyogo, JapanOTHER | 7 | Jan 29, 2026 | clinicaltrials |
| NCT02591407 | Trial Comparing Transversus Abdominis Plane Block Versus Epidural Anesthesia for Pain Management in Colorectal Surgery(TAP) | completed | N/A | 200 | Trinity Health MichiganOTHER | 1 | Jan 28, 2026 | clinicaltrials |
| NCT04362839 | Regorafenib, Ipilimumab and Nivolumab for the Treatment of Chemotherapy Resistant Microsatellite Stable Metastatic Colorectal Cancer | completed | Phase 1 | 39 | City of Hope Medical CenterOTHER | 1 | Jan 28, 2026 | clinicaltrials |
| NCT04640480 | Dose-finding Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SNB-101(SN-38) in Patients With Tumors | completed | Phase 1 | 21 | SN BioScienceINDUSTRY | 1 | Jan 27, 2026 | clinicaltrials |
| NCT07085845 | The Self-Sampling Pilot Study(SOLOPilot) | completed | N/A | 50 | Medical College of WisconsinOTHER | 1 | Jan 27, 2026 | clinicaltrials |
| NCT05040568 | A PHASE IB STUDY OF IMMUNOTHERAPY WITH EX VIVO PRE-ACTIVATED AND EXPANDED CB-NK CELLS IN COMBINATION WITH CETUXIMAB, IN COLORECTAL CANCER PATIENTS WITH MINIMAL RESIDUAL DISEASE (MRD) | completed | Phase 1 | 15 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 26, 2026 | clinicaltrials |
| NCT04593277 | Interactive Survivorship Program for the Improvement of Healthcare Resources in Adolescent and Young Adult Cancer Survivors, INSPIRE-AYA Study | completed | N/A | 549 | Fred Hutchinson Cancer CenterOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT05360680 | A Phase 1 in Patients With HLA-A*0201+ and WT1+ Recurrent/Metastatic Cancers | completed | Phase 1 | 42 | Cue BiopharmaINDUSTRY | 1 | Jan 22, 2026 | clinicaltrials |
| NCT05641896 | Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers(18F-FAPI-74 GI) | completed | Phase 2 | 109 | SOFIEINDUSTRY | 1 | Jan 22, 2026 | clinicaltrials |
| NCT05746195 | Optimization of Adaptive Text Messages for Cancer Survivors (OATS II) | completed | N/A | 46 | University of California, San FranciscoOTHER | 1 | Jan 22, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Mar 6, 2026source: clinicaltrials