Clinical trial · Observational
Efficacy of Colonoscopy, Colon Capsule and Fecal Immunological Test for Colorectal Cancer Screening
Efficacy of Colonoscopy, Colon Capsule and Fecal Immunological Test for Colorectal Cancer Screening, in First Degree Relatives of Patients With Colorectal Neoplasia: a Prospective Randomized Study.
NCT02738359CI-TRIAL-00104263FAMCAPcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Efficacy of colonoscopy, colon capsule and fecal immunological test for colorectal cancer screening, in first degree relatives of patients with colorectal neoplasia: a prospective randomized study.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Rectum Cancer | Rectal Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| colon capsule endoscopy | Procedure | — | UNRESOLVED |
| fecal immunological test (FIT) | Diagnostic Test | — | UNRESOLVED |
| optical colonoscopy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- 1rst arm: optical colonoscopy (OC)
- description
- t0: optical colonoscopy; Follow-up: yearly by phone call for three years
- interventionNames
- Procedure: optical colonoscopy
- label
- 2nd arm: colon capsule endoscopy (CC)
- description
- t0: colon capsule endoscopy -\> if positive: OC; At three years: OC for those patients with negative initial CC; Follow-up: yearly by phone call for 3 years
- interventionNames
- Procedure: optical colonoscopy
- Procedure: colon capsule endoscopy
- label
- 3rd arm: fecal immunological test (FIT)
- description
- FIT yearly for two years: t0: FIT -\> if positive : OC; t = 1 year: FIT -\> if positive : OC; t = 2 years: FIT -\> if positive : OC; At three years: OC for those patients with negative FIT during the study Follow-up: yearly by phone call for 3 years
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 45 Years
Show eligibility criteria text
Inclusion criteria: * History of colorectal cancers (any age) in first-degree relatives (parents, children, siblings including half-brothers and sisters) * Age \> or = 45 years * No previous colorectal cancer screening * Informed patient * Patient having signed the consent form * Patient affiliated to a social security system or recipient of such system Exclusion criteria: * Any previous colorectal cancer screening: * History of blood tests in the stool (hemoccult, fecal immunological test, ...) * History of colonic capsule screening * History of colonoscopy * Any known advanced neoplasia or colorectal cancer * Known genetic predisposition to colorectal cancer (very high risk group) * Adults protected by law (under guardianship or trusteeship) * Other metastatic cancers * Life-threatening diseases
References
Publications (0)
Data not yet available
No reference posted for this study.