Clinical trial · Observational
International Prospective Observational Cohort Study for Optimal Bowel Resection Extent and Central Radicality for Colon Cancer
NCT02938481CI-TRIAL-00101927T-REXcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The T-REX study aims to clarify the actual status of metastatic lymph node (LN) distribution in colon cancer and provide reliable evidence regarding the optimal length of bowel resection and the extent of central lymph node dissection in colon cancer surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- Distribution of metastatic LNs
- timeFrame
- At the time of patient registry in
- measure
- Distribution of metastatic LNs
- timeFrame
- At the time of 4 years after surgery
Secondary outcomes (2)
- measure
- Prognostic outcomes according to the length of bowel resection
- timeFrame
- 4 years
- measure
- Prognostic outcomes according to the central radicality
- timeFrame
- 4 years
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Histologically proven colon adenocarcinoma * Pathological stage Ⅰ, Ⅱ or Ⅲ * Potentially curative surgery * Informed consent for observational data collection Exclusion Criteria: * Tis (mucosal cancer) * Multiple colon cancers * All patients with preoperative adjuvant therapy
References
Publications (1)
- DERIVEDShiozawa M, Ueno H, Shiomi A, Kim NK, Kim JC, Tsarkov P, Grutzmann R, Dulskas A, Liang JT, Samalavicius N, West N, Sugihara K. Study protocol for an International Prospective Observational Cohort Study for Optimal Bowel Resection Extent and Central Radicality for Colon Cancer (T-REX study). Jpn J Clin Oncol. 2021 Jan 1;51(1):145-155. doi: 10.1093/jjco/hyaa115. PMID 33215206