Clinical trial · Observational
Proof-of-concept Study of Blood Markers of Tumor Dissemination in Patients With Versus Without Intestinal Polyps
NCT05648240CI-TRIAL-00102922EARDIScompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study authors hypothesize that in patients with intestinal polyps, tumor cells could disseminate and circulating factors could be secreted by the polyp. These two parameters could become biomarkers to refine the follow-up of patients and to establish targeted therapeutic strategies.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Disseminated Cancer | — | UNRESOLVED | — |
| Neoplasm Metastasis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood test | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Patients with polyps
- interventionNames
- Other: Blood test
- label
- Patients without polyps
- interventionNames
- Other: Blood test
Primary outcomes (1)
- measure
- Dissemination of circulating tumor cells in blood samples from patients with intestinal polyps compared to patients without polyps
- timeFrame
- Day 0
- description
- Number of disseminated circulating tumor cells found on the ANGLE Parsortix™ system
Secondary outcomes (23)
- measure
- Concentration of Macrophage Colony Stimulating Factor (M-CSF) in the blood samples between groups
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient to be examined by colonoscopy * The patient must be a member or beneficiary of a health insurance plan Exclusion Criteria: * The subject is participating in a category 1 interventional study, or is in a period of exclusion determined by a previous study * The subject signals their opposition to participate in the study * It is impossible to give the subject informed information * The patient is under safeguard of justice or state guardianship * Patient pregnant or breastfeeding * History of proven cancerous disease * Patient followed for a chronic inflammatory bowel disease
References
Publications (0)
Data not yet available
No reference posted for this study.