Subtype
Malignant Large Intestinal Neoplasm
CI-CAN-00003173Explore in graph →
1,622 active trials21 approved drugs383 evidence items
- NCIt
- C215202
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Subtype
CI-CAN-00003173Explore in graph →
Clinical trials
7,502 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (742)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04513951 | AVELUMAB and CETUXIMAB and mFOLFOXIRI as Initial Therapy for Unresectable Metastatic Colorectal Cancer Patients(AVETRIC) | completed | Phase 2 | 62 | Gruppo Oncologico del Nord-OvestOTHER | 1 | Jan 9, 2025 | clinicaltrials |
| NCT05716477 | Blood Test (Guardant Shield™) for Screening of Colorectal Cancer in Underserved Patients | completed | — | 146 | Ohio State University Comprehensive Cancer CenterOTHER | 1 |
| Jan 9, 2025 |
| clinicaltrials |
| NCT03511963 | A Clinical Study to Compare the Efficacy, Safety and Immunogenicity of HLX04 and Bevacizumab Combined XELOX or mFOLFOX6 in the First-line Treatment of mCRC | completed | Phase 3 | 677 | Shanghai Henlius BiotechINDUSTRY | 1 | Dec 31, 2024 | clinicaltrials |
| NCT06753968 | The Role of Natural Orifice Specimen Extraction Surgery (NOSES) in Treating Right-sided Colon Cancer | completed | N/A | 349 | National Cancer Center, ChinaOTHER | 1 | Dec 31, 2024 | clinicaltrials |
| NCT04731467 | A Study of CM24 in Combination with Nivolumab in Adults with Advanced Solid Tumors | completed | Phase 1 / Phase 2 | 79 | Famewave Ltd.INDUSTRY | 3 | Dec 27, 2024 | clinicaltrials |
| NCT05646355 | Flatbush FHC Proactive Colorectal Cancer Screening and Navigation | completed | N/A | 109 | NYU Langone HealthOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT05707598 | Multivisceral Radical Resection for Surgical T4b Colorectal Cancer: Propensity Score-matched Study Comparing the the Laparoscopic and Open Approaches(C-PelvEx-01) | completed | — | 638 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT06748339 | Gut Microbiome and Colorectal Cancer | completed | — | 18 | Heliopolis UniversityOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT02861300 | CB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal Cancer | completed | Phase 1 / Phase 2 | 50 | David Bajor, MDOTHER | 1 | Dec 19, 2024 | clinicaltrials |
| NCT04028479 | The Registry of Oncology Outcomes Associated With Testing and Treatment(ROOT) | completed | — | 167 | Taproot HealthINDUSTRY | 1 | Dec 18, 2024 | clinicaltrials |
| NCT06508541 | The Prognosis of Colorectal Cancer Patients After Indocyanine Green Fluorescence-guided Radical Surgery | completed | — | 235 | Shanghai Tong Ren HospitalOTHER | 1 | Dec 16, 2024 | clinicaltrials |
| NCT01640522 | Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms(CaSSY) | completed | N/A | 261 | University of PittsburghOTHER | 1 | Dec 13, 2024 | clinicaltrials |
| NCT01950403 | Linaclotide Acetate in Preventing Colorectal Cancer in Healthy Volunteers | completed | Phase 1 | 24 | Mayo ClinicOTHER | 1 | Dec 9, 2024 | clinicaltrials |
| NCT01461525 | Comparison of Sphincter Preservation Surgery and Abdominoperineal Resection (APR): Prospective Clinical Trial(ASPIRE) | completed | N/A | 342 | Seoul National University HospitalOTHER | 1 | Dec 5, 2024 | clinicaltrials |
| NCT06717763 | Surgery Following Immune Checkpoint Inhibitions for Controlled Disease in Recurrent or Metastatic dMMR/MSI-H Colorectal Cancer | completed | — | 40 | Sun Yat-sen UniversityOTHER | 1 | Dec 5, 2024 | clinicaltrials |
| NCT03564938 | Regorafenib in Indian Patients With Metastatic Colorectal Cancer (mCRC). | completed | Phase 4 | 100 | BayerINDUSTRY | 1 | Dec 3, 2024 | clinicaltrials |
| NCT03665506 | Trifluridin/tipirACil in MeTastatIc Colorectal Cancer(TACTIC) | completed | — | 315 | ServierINDUSTRY | 1 | Dec 3, 2024 | clinicaltrials |
| NCT05060471 | PD-1 Blockade Combined With Chemotherapy Followed by Concurrent Immunoradiotherapy for Locally Advanced SCCA Patients | completed | Phase 2 | 25 | Sun Yat-sen UniversityOTHER | 1 | Dec 3, 2024 | clinicaltrials |
| NCT05153954 | Quantitative ICG Fluorescence Angiography in Colorectal Surgery(QUANTICO) | completed | — | 114 | Zealand University HospitalOTHER | 1 | Dec 3, 2024 | clinicaltrials |
| NCT04842968 | Ex Vivo Intraarterial Methylene Blue Injection Improve Nodal Staging Accuracy in Colorectal Cancer(MB) | completed | N/A | 200 | St. Borbala HospitalOTHER_GOV | 1 | Dec 2, 2024 | clinicaltrials |
| NCT03828318 | Impact of a Patient-Centered Program for Low Anterior Resection Syndrome a Multicenter Randomized Controlled Trial | completed | N/A | 160 | Jewish General HospitalOTHER | 2 | Nov 29, 2024 | clinicaltrials |
| NCT04595604 | Long Term Effect of Trimodal Prehabilitation Compared to ERAS in Colorectal Cancer Surgery.(Prehab_2) | completed | N/A | 500 | St. Borbala HospitalOTHER_GOV | 1 | Nov 29, 2024 | clinicaltrials |
| NCT04926376 | Safety and Effectiveness of Eye90 Microspheres™ in the Treatment of Unresectable Hepatocellular Carcinoma (HCC) and Metastatic Colorectal Cancer (mCRC) | completed | N/A | 8 | ABK BiomedicalINDUSTRY | 1 | Nov 29, 2024 | clinicaltrials |
| NCT05396807 | REVERT - taRgeted thErapy for adVanced colorEctal canceR paTients(REVERT) | completed | N/A | 106 | University of Rome Tor VergataOTHER | 3 | Nov 29, 2024 | clinicaltrials |
| NCT03436563 | M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability | completed | Phase 1 / Phase 2 | 4 | M.D. Anderson Cancer CenterOTHER | 1 | Nov 27, 2024 | clinicaltrials |
| NCT06704646 | Predictors of One-Year Mortality After Curative Surgery in Patients Aged 80 Years or Older With Non-Metastatic Colorectal Cancer | completed | — | 310 | National Taiwan University HospitalOTHER | 0 | Nov 27, 2024 | clinicaltrials |
| NCT03043313 | Tucatinib Plus Trastuzumab in Patients With HER2+ Colorectal Cancer | completed | Phase 2 | 117 | Seagen Inc.INDUSTRY | 5 | Nov 26, 2024 | clinicaltrials |
| NCT01539824 | A Study of IMM-101 in Combination With Radiation Induced Tumour Necrosis in Colorectal Cancer | completed | Phase 2 | 12 | Immodulon Therapeutics LtdINDUSTRY | 1 | Nov 25, 2024 | clinicaltrials |
| NCT05461248 | Stoma Discharge Reinfusion After Sphincter Preservation for Middle and Low Rectal Cancer | completed | N/A | 60 | The First Hospital of Jilin UniversityOTHER | 1 | Nov 22, 2024 | clinicaltrials |
| NCT01741363 | Screening for Stomach Diseases and Colorectal Neoplasms With the Fecal Testing | completed | N/A | 99,314 | National Taiwan University HospitalOTHER | 1 | Nov 21, 2024 | clinicaltrials |
| NCT03374254 | Safety and Efficacy of Pembrolizumab (MK-3475) Plus Binimetinib Alone or Pembrolizumab Plus Chemotherapy With or Without Binimetinib in Metastatic Colorectal Cancer (mCRC) Participants (MK-3475-651/KEYNOTE-651) | completed | Phase 1 | 116 | Merck Sharp & Dohme LLCINDUSTRY | 2 | Nov 21, 2024 | clinicaltrials |
| NCT03699163 | The Colorectal Breath Analysis (COBRA) Study(COBRA) | completed | — | 1,855 | Imperial College LondonOTHER | 1 | Nov 21, 2024 | clinicaltrials |
| NCT04357158 | Breath Analysis as an Additional Test for Colorectal Cancer Screening to Reduce the Number of Unnecessary Colonoscopies(SCREENER) | completed | N/A | 750 | Radboud University Medical CenterOTHER | 1 | Nov 21, 2024 | clinicaltrials |
| NCT04700410 | Bowel Cleansing Performance of the Pure-Vu System in Patients With a History of Poor Bowel Preparation | completed | N/A | 44 | Radboud University Medical CenterOTHER | 2 | Nov 21, 2024 | clinicaltrials |
| NCT05242562 | Effect of Low-volume (1L) vs Intermediate-volume (2L) Bowel Preparation on Cost-effectiveness and Quality of Life(RESULT) | completed | N/A | 509 | Radboud University Medical CenterOTHER | 1 | Nov 21, 2024 | clinicaltrials |
| NCT06684223 | Analysis of Surgical and Oncologic Outcomes After Complete Mesocolic Excision or Non-complete Mesocolic Excision for Right-Sided Colon Cancer | completed | — | 3,787 | Asan Medical CenterOTHER | 1 | Nov 20, 2024 | clinicaltrials |
| NCT03225989 | Trial Investigating an Immunostimulatory Oncolytic Adenovirus for Cancer | completed | Phase 1 / Phase 2 | 47 | Lokon Pharma ABINDUSTRY | 1 | Nov 19, 2024 | clinicaltrials |
| NCT03761914 | Galinpepimut-S in Combination With Pembrolizumab in Patients With Selected Advanced Cancers | completed | Phase 1 / Phase 2 | 26 | Sellas Life Sciences GroupINDUSTRY | 1 | Nov 19, 2024 | clinicaltrials |
| NCT05064670 | Exercise as Medicine for People With Cancer Sweden(EX-MED) | completed | N/A | 200 | Karolinska InstitutetOTHER | 1 | Nov 18, 2024 | clinicaltrials |
| NCT05784597 | A Study to Evaluate the Safety and Dosimetry of 68Ga-labelled OncoFAP Derivatives in Solid Tumors(FAPrimo) | completed | Phase 1 | 18 | Philogen S.p.A.INDUSTRY | 1 | Nov 15, 2024 | clinicaltrials |
| NCT06686953 | The Effect of Environmental Pollution on Colorectal Cancer | completed | — | 6,300 | Dong PengOTHER | 0 | Nov 13, 2024 | clinicaltrials |
| NCT03489707 | The Prevent Anal Cancer Self-Swab Study | completed | N/A | 253 | Medical College of WisconsinOTHER | 1 | Nov 12, 2024 | clinicaltrials |
| NCT06655285 | The Impact of Inflammatory Adhesion on the Prognosis of Colon Cancer Patients | completed | — | 229 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Nov 7, 2024 | clinicaltrials |
| NCT06674200 | A Retrospective Study Comparing the Incidence of Parastomal Hernia After Mesenteric Molding Suturing and Non-molding Suturing in Colostomy Surgery(COMPARISON) | completed | N/A | 11,243 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 0 | Nov 5, 2024 | clinicaltrials |
| NCT05348187 | Clinical Performance Study Protocol for Therascreen® KRAS RGQ PCR Kit | completed | N/A | 309 | QIAGEN Gaithersburg, IncINDUSTRY | 1 | Nov 4, 2024 | clinicaltrials |
| NCT04456699 | Efficacy and Safety of Olaparib (MK-7339) With or Without Bevacizumab Compared to Bevacizumab With a Fluoropyrimidine in Unresectable or Metastatic Colorectal Cancer (CRC) (MK-7339-003/LYNK-003) | completed | Phase 3 | 335 | Merck Sharp & Dohme LLCINDUSTRY | 18 | Oct 29, 2024 | clinicaltrials |
| NCT02494973 | Postoperative Hepatic Arterial Chemotherapy in High-risk Patients as Adjuvant Treatment After Resection of Colorectal Liver Metastases(PACHA-01) | completed | Phase 2 / Phase 3 | 104 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | Oct 28, 2024 | clinicaltrials |
| NCT02040142 | HIPEC for Peritoneal Carcinomatosis | completed | Phase 2 | 51 | Albert Einstein College of MedicineOTHER | 1 | Oct 24, 2024 | clinicaltrials |
| NCT00807911 | Adjuvant Chemotherapy After Preoperative Chemoradiotherapy to Treat Rectal Cancer | completed | Phase 2 | 322 | Asan Medical CenterOTHER | 1 | Oct 23, 2024 | clinicaltrials |
Data updated 24 days agoSource updated Jan 9, 2025source: clinicaltrials