Clinical trial · Observational
Multivisceral Radical Resection for Surgical T4b Colorectal Cancer: Propensity Score-matched Study Comparing the the Laparoscopic and Open Approaches
NCT05707598CI-TRIAL-00084135C-PelvEx-01completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study attempts to compare safety and long-term oncological outcomes between laparoscopic surgery and open surgery in the treatment of clinical T4b Colorectal cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laparoscopic surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Laparoscopic multivisceral resection group
- description
- Patients who underwent laparoscopic multivisceral resection for clinical T4b colorectal cancer
- interventionNames
- Procedure: Laparoscopic surgery
- label
- Open multivisceral resection group
- description
- Patients who underwent open multivisceral resection for clinical T4b colorectal cancer
Primary outcomes (3)
- measure
- Blood loss
- timeFrame
- Until the end of the operation, an average of 8 hours.
- description
- Blood loss is defined as intraoperative blood loss and measured in milliliters(ml).
- measure
- Complications
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. The patient was pathologically diagnosed as colorectal adenocarcinoma by endoscopic biopsy before operation. 2. All patients were considered to have tumors invading adjacent organs after preoperative radiographic evaluation. 3. All patients were recommended to undergo radical surgery after preoperative multidisciplinary consultation. Exclusion Criteria: Patients with distant metastasis or recurrent colorectal cancer were excluded.
References
Publications (1)
- DERIVEDZhang J, Sun J, Liu J, Mei S, Quan J, Hu G, Li B, Zhuang M, Wang X, Tang J. Comparison of short- and long-term outcomes between laparoscopic and open multivisceral resection for clinical T4b colorectal cancer: A multicentre retrospective cohort study in China. Eur J Surg Oncol. 2024 Jan;50(1):107316. doi: 10.1016/j.ejso.2023.107316. Epub 2023 Dec 7. PMID 38086316