Clinical trial · Observational
Analysis of Surgical and Oncologic Outcomes After Complete Mesocolic Excision or Non-complete Mesocolic Excision for Right-Sided Colon Cancer
Analysis of Surgical and Oncologic Outcomes After Compete Mesocolic Excision or Non-complete Mesocolic Excision for Right-Sided Colon Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to investigate the efficacy and safety of a modified D3 lymphadenectomy approach compared to Complete Mesocolic Excision (CME) in patients with right-sided colon cancer. The main question it aims to answer is: Does a modified D3 approach improve disease-free survival (DFS) in patients with Stage I-III right-sided colon cancer who undergo right-sided colectomy, without increasing surgical complications compared to CME? Patients with right-sided colon cancer, Stage I-III, who undergo either modified D3 lymphadenectomy or CME as part of their standard treatment, will have their DFS, complications, bleeding volume, number of lymph nodes harvested, and stage distribution compared over a follow-up period. This study ultimately aims to determine the optimal surgical approach for maximizing oncologic outcomes in right-sided colon cancer.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Laparoscopic Colon Surgery | — | UNRESOLVED | — |
| Lymph Node Dissection | — | UNRESOLVED | — |
| Robotic Surgical Procedures | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Patients who underwent laparoscopic or robotic right hemicolectomy with modifiedD3 from 2013 to 2020
- description
- Patients who underwent laparoscopic or robotic right hemicolectomy with modified D3 lymphadenectomy from 2013 to 2020 in 4 centers
- label
- Patients who underwent laparoscopic or robotic right hemicolectomy with CME from 2013 to 2020
- description
- Patients who underwent laparoscopic or robotic right hemicolectomy with Complete mesocolic excision from 2013 to 2020 in 4 centers
Primary outcomes (1)
- measure
- Recurrence free survival
- timeFrame
- Outcome measures will be assessed at 5 years post-surgery.
- description
- Recurrence-Free Survival (RFS) between patients who underwent modified D3 and CME procedures from 2013 to 2020.
Secondary outcomes (1)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Patients who underwent laparoscopic or robotic right hemicolectomy from 2013 to 2020 * Patients who received curative right hemicolectomy with lymphadenectomy Exclusion Criteria: * Familial adenomatous polyposis (FAP) * Hereditary non-polyposis colon cancer (HNPCC) * Patients with inflammatory bowel disease * Patients with synchronous malignancies in other organs * Patients with non-adenocarcinoma histology of colon cancer
References
Publications (0)
Data not yet available