Cancer Family
Malignant Head and Neck Neoplasm
CI-CAN-00000236Explore in graph →
1,431 active trials17 approved drugs142 evidence items
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Cancer Family
CI-CAN-00000236Explore in graph →
Clinical trials
5,448 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (629)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07471009 | Development of Patient Derived Xenografts (PDXs) and Analysis of Tyrosine Kinase Receptor Expression in Patients With Squamous Cell Head and Neck Cancer (HNSCC) to Study Resistance Mechanisms Induced by Standard Therapy(SPAR) | not yet recruiting | — | 120 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 1 | Mar 13, 2026 | clinicaltrials |
| NCT07457099 | Impact of Postoperative Radiotherapy Versus PD-1 Inhibitor Maintenance on Survival in Resectable Locally Advanced Oral and Oropharyngeal Squamous Cell Carcinoma | not yet recruiting | — | 85 |
| Zhujiang HospitalOTHER |
| 1 |
| Mar 9, 2026 |
| clinicaltrials |
| NCT07193186 | Anlotinib and Benmelstobart in DTC | not yet recruiting | Phase 2 | 23 | Fudan UniversityOTHER | 0 | Feb 27, 2026 | clinicaltrials |
| NCT07437326 | Food-related Quality of Life in Patients With Cancer(QVA-Mod) | not yet recruiting | — | 180 | Hospices Civils de LyonOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT07432087 | Camrelizumab Combined With EGFR Monoclonal Antibody or Chemotherapy for Perioperative Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma | not yet recruiting | Phase 3 | 246 | Yue He, MDOTHER | 0 | Feb 25, 2026 | clinicaltrials |
| NCT07428148 | Lattice-Based Radiotherapy and Chemoimmunotherapy for Oropharyngeal Squamous Cell Carcinoma | not yet recruiting | Phase 1 / Phase 2 | 60 | NYU Langone HealthOTHER | 1 | Feb 23, 2026 | clinicaltrials |
| NCT07381699 | MRG003 Combined With Immunotherapy in Recurrent/Metastatic Nasopharyngeal Carcinoma: A Phase II Clinical Trial | not yet recruiting | Phase 2 | 30 | West China HospitalOTHER | 0 | Feb 13, 2026 | clinicaltrials |
| NCT07405320 | A Brief Video Intervention to Improve Patient Outcomes Following Radioiodine Treatment | not yet recruiting | N/A | 80 | University of Auckland, New ZealandOTHER | 0 | Feb 12, 2026 | clinicaltrials |
| NCT07402538 | Surgery With or Without Neoadjuvant Treatment of SBRT Plus Chemoimmunotherapy in Resectable Locally Advanced Oral and HPV-unrelated Oropharyngeal Squamous Cell Carcinoma | not yet recruiting | Phase 3 | 184 | Sun Yat-sen UniversityOTHER | 1 | Feb 11, 2026 | clinicaltrials |
| NCT06647602 | Thyroid Hormone Replacement After Radio Iodine: Value and Efficacy(THRIVE) | not yet recruiting | — | 40 | University Medical Center GroningenOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT07399158 | CROSSROAD: Treatment Regimen Switch - Re-induction Chemotherapy vs. Direct Radiotherapy in LANPC With Inadequate Response to Induction Chemotherapy | not yet recruiting | — | 223 | Fujian Cancer HospitalOTHER_GOV | 0 | Feb 10, 2026 | clinicaltrials |
| NCT07400094 | Neoadjuvant Chemoimmunotherapy (Camrelizumab + Paclitaxel + Carboplatin) for Resectable HNSCC(NeoCamre-HN) | not yet recruiting | Phase 2 | 50 | National Medical Research Radiological Centre of the Ministry of Health of RussiaOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT06790589 | COACH - Comparing Two Different Methods to Suppress Thyrotropin in Patients With Advanced Thyroid Cancer | not yet recruiting | Phase 2 | 70 | AHS Cancer Control AlbertaOTHER | 0 | Feb 6, 2026 | clinicaltrials |
| NCT07393477 | Neoadjuvant Becotatug Vedotin Plus Pucotenlimab and Cisplatin for Locally Advanced Head and Neck Squamous Cell Carcinoma | not yet recruiting | Phase 2 | 30 | Sir Run Run Shaw HospitalOTHER | 1 | Feb 6, 2026 | clinicaltrials |
| NCT07388758 | Scipibaimab Combined With Tislelizumab in Patients With First-Line Treatment-Failed Recurrent/Metastatic Nasopharyngeal Carcinoma | not yet recruiting | Phase 2 | 37 | Sun Yat-sen UniversityOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT07388836 | Timing Optimization of Immunotherapy During Neoadjuvant Chemotherapy for Locally Advanced Nasopharyngeal Carcinoma | not yet recruiting | Phase 2 | 198 | Fujian Cancer HospitalOTHER_GOV | 0 | Feb 5, 2026 | clinicaltrials |
| NCT07385079 | Anlotinib Plus Immunotherapy and Chemoradiotherapy for High-Risk Nasopharyngeal Carcinoma | not yet recruiting | Phase 3 | 412 | Sun Yat-sen UniversityOTHER | 0 | Feb 3, 2026 | clinicaltrials |
| NCT07379424 | A Single-arm, Phase II, Multi-center Clinical Trial of Sintilimab During the Perioperative Period in Patients With Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma | not yet recruiting | Phase 2 | 37 | chen chao ProfessorOTHER | 1 | Jan 30, 2026 | clinicaltrials |
| NCT07335380 | Lattice-Based Radiotherapy and Chemo-Immunotherapy for Oral Cavity Squamous Cell Carcinoma | not yet recruiting | Phase 1 | 30 | NYU Langone HealthOTHER | 1 | Jan 29, 2026 | clinicaltrials |
| NCT07371897 | Toripalimab ± Chemo as Neoadjuvant Therapy in LA-HNSCC: A Phase III Trial(SHINE) | not yet recruiting | Phase 3 | 154 | Sun Yat-sen UniversityOTHER | 0 | Jan 28, 2026 | clinicaltrials |
| NCT07373990 | Short-course Tislelizumab Combined With Chemoradiotherapy for Nasopharyngeal Carcinoma | not yet recruiting | Phase 3 | 418 | Sun Yat-sen UniversityOTHER | 0 | Jan 28, 2026 | clinicaltrials |
| NCT07361666 | Impact of Preoperative High-Frequency Ultrasound Cutaneous Lesion Extent Assessment on Excision Margin Positivity in Head and Neck Skin Cancer, and the Relationship Between Preoperative Assessment Methods, Inadequate Excision Margins, and Tumor Recurrence(HFUS-CLEAR) | not yet recruiting | — | 400 | Państwowy Instytut Medyczny Ministerstwa Spraw Wewnętrznych i AdministracjiOTHER_GOV | 1 | Jan 23, 2026 | clinicaltrials |
| NCT07225725 | Access to Care Pilot for ED-Presenting Head and Neck Cancer Patients (ENRICH-HNC)(ENRICH-HNC) | not yet recruiting | N/A | 24 | University of TennesseeOTHER | 1 | Jan 22, 2026 | clinicaltrials |
| NCT07357506 | Reducing Skin Side Effects in Patients Receiving Radiation on Tomotherapy(MCTPUT) | not yet recruiting | N/A | 104 | King Faisal Specialist Hospital & Research CenterOTHER | 0 | Jan 22, 2026 | clinicaltrials |
| NCT07358884 | First in Human Study of QLS5316 in Solid Tumors | not yet recruiting | Phase 1 | 300 | Qilu Pharmaceutical Co., Ltd.INDUSTRY | 0 | Jan 22, 2026 | clinicaltrials |
| NCT07354698 | Application of Mitoxantrone Hydrochloride Injection in Transoral Robotic Thyroid Cancer Surgery(MHI) | not yet recruiting | Phase 4 | 114 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT07354984 | A Single-Arm Phase II Clinical Study of Docetaxel Combined With Nimotuzumab and Pucotenlimab as Second-Line and Beyond Therapy for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma(PIONEER-HN) | not yet recruiting | Phase 2 | 30 | Sun Yat-sen UniversityOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT07346807 | Lingual Nerve Disruption to Augment Neoadjuvant Chemoimmunotherapy in Locally Advanced Tongue Cancer | not yet recruiting | Phase 2 | 69 | Shanghai Zhongshan HospitalOTHER | 1 | Jan 16, 2026 | clinicaltrials |
| NCT07331428 | MRG003 Induction and Capecitabine Maintenance With PD-1 in Locally Recurrent NPC | not yet recruiting | Phase 2 | 25 | Fujian Cancer HospitalOTHER_GOV | 0 | Jan 9, 2026 | clinicaltrials |
| NCT07324317 | Validation of End-to-End Difficult Airway Pathway Planning Algorithm (EAP-LC) | not yet recruiting | — | 70 | Eye & ENT Hospital of Fudan UniversityOTHER | 0 | Jan 7, 2026 | clinicaltrials |
| NCT07320690 | De-Escalation Surgery After Immunotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma(Neo-Margin) | not yet recruiting | Phase 3 | 356 | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityOTHER | 1 | Jan 6, 2026 | clinicaltrials |
| NCT07310771 | Sintilimab-Nimotuzumab Induction Followed by Chemoradiation-Nimotuzumab in LA-HNSCC: Single-Arm Phase II | not yet recruiting | Phase 2 | 23 | Fujian Cancer HospitalOTHER_GOV | 0 | Dec 30, 2025 | clinicaltrials |
| NCT07172776 | A Community Engagement Approach to Improving Communication With Black Men About Oral and Pharyngeal Cancers | not yet recruiting | N/A | 50 | University of Illinois at ChicagoOTHER | 0 | Dec 29, 2025 | clinicaltrials |
| NCT07306546 | Effectiveness of Hydrogen Water Intervention on Acute Oral Inflammation, Oral Microbiota, and Pain Following Free Flap Reconstruction in Patients With Oral Cancer | not yet recruiting | N/A | 36 | Kaohsiung Medical University Chung-Ho Memorial HospitalOTHER | 0 | Dec 29, 2025 | clinicaltrials |
| NCT05912582 | Prospective Study for Molecular Biomarkers and Spatial Transcriptomics of Nasopharyngeal Carcinoma | not yet recruiting | — | 60 | Jiangsu Cancer Institute & HospitalOTHER | 1 | Dec 26, 2025 | clinicaltrials |
| NCT07301047 | App-Assisted Swallowing Program After Oral Cancer Surgery(AASP) | not yet recruiting | N/A | 72 | Chang Gung Memorial HospitalOTHER | 1 | Dec 24, 2025 | clinicaltrials |
| NCT07299318 | Multimodal Deep Learning for Lymph Node Metastasis in Thyroid Cancer | not yet recruiting | — | 3,200 | West China HospitalOTHER | 1 | Dec 23, 2025 | clinicaltrials |
| NCT07274605 | Comparing the Therapeutic Efficacy of Extended Isthmusectomy Versus Total Thyroidectomy for Isthmus Tumors of the Thyroid | not yet recruiting | N/A | 520 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Dec 10, 2025 | clinicaltrials |
| NCT07268690 | Risk-Adapted Omission of Level Va Irradiation in Nasopharyngeal Carcinoma | not yet recruiting | Phase 3 | 474 | Fujian Cancer HospitalOTHER_GOV | 1 | Dec 8, 2025 | clinicaltrials |
| NCT07267338 | Pembrolizumab + MRGOO3 as Neoadjuvant in NPC | not yet recruiting | Phase 2 | 35 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Dec 5, 2025 | clinicaltrials |
| NCT07259915 | Multimodal Prediction of Response to Chemoradiotherapy for Squamous Cell Carcinoma of the Head and Neck(MULTINECK) | not yet recruiting | N/A | 152 | Centre Henri BecquerelOTHER | 1 | Dec 2, 2025 | clinicaltrials |
| NCT07252661 | Study of ACC-1898 in Adult Participants With Advanced Solid Tumors | not yet recruiting | Phase 1 | 40 | AccSalus Biosciences, Inc.INDUSTRY | 0 | Nov 28, 2025 | clinicaltrials |
| NCT07254962 | CApecitabine Prior to TUmor Resection in Ent Oncology (CAPTURE)(CAPTURE) | not yet recruiting | Phase 2 | 75 | Sir Mortimer B. Davis - Jewish General HospitalOTHER | 0 | Nov 28, 2025 | clinicaltrials |
| NCT07252375 | A Clinical Study of Hetrombopag for Prevention of Thrombocytopenia Induced by Gemcitabine Plus Cisplatin in the Treatment of Nasopharyngeal Carcinoma | not yet recruiting | Phase 2 | 35 | Fujian Cancer HospitalOTHER_GOV | 0 | Nov 26, 2025 | clinicaltrials |
| NCT07252557 | Mouthwash Temperature and Oral Mucositis in Head and Neck Radiotherapy(CoolRinseHNC) | not yet recruiting | N/A | 200 | Chung Shan Medical UniversityOTHER | 1 | Nov 26, 2025 | clinicaltrials |
| NCT07246759 | Neutrophil Biomarker Test for Predicting Clinical Benefit From Immunotherapy Based on Flow Cytometry Analysis(NEUTROFLOW) | not yet recruiting | — | 600 | OncoHost Ltd.INDUSTRY | 3 | Nov 24, 2025 | clinicaltrials |
| NCT07238569 | Phase III Trial of EBV-DNA-Guided Adaptive Immunotherapy for Advanced Nasopharyngeal Carcinoma | not yet recruiting | Phase 3 | 516 | Sun Yat-sen UniversityOTHER | 0 | Nov 20, 2025 | clinicaltrials |
| NCT07210749 | Radiotherapy 12Gy in 6 Fractions For Orbital Lymphoma | not yet recruiting | N/A | 36 | British Columbia Cancer AgencyOTHER | 1 | Oct 7, 2025 | clinicaltrials |
| NCT07198802 | Molecular Research on Predictive Efficacy and New Therapeutic Targets for Nasopharyngeal Carcinoma | not yet recruiting | — | 600 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 0 | Sep 30, 2025 | clinicaltrials |
| NCT07185958 | Dual Energy CT - a Tool for Delineation of Tumor and Organs at Risk in Radiotherapy(DART) | not yet recruiting | — | 80 | Aalborg University HospitalOTHER | 1 | Sep 22, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Mar 13, 2026source: clinicaltrials