Cancer Family
Malignant Head and Neck Neoplasm
CI-CAN-00000236Explore in graph →
1,432 active trials17 approved drugs142 evidence items
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Cancer Family
CI-CAN-00000236Explore in graph →
Clinical trials
5,449 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (629)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07543887 | Selpercatinib and Body Composition(EECRTKI) | completed | — | 15 | University of PisaOTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT03621696 | Surgery Followed by Risk-Directed Post-Operative Adjuvant Therapy for HPV-Related Oropharynx Squamous Cell Carcinoma: "The Minimalist Trial (MINT)"(MINT) | completed | Phase 2 | 63 | Washington University School of MedicineOTHER | 1 |
| Apr 21, 2026 |
| clinicaltrials |
| NCT07029373 | Plasma Calcitonin Gene-Related Peptide (CGRP) Levels in Patients With Head and Neck Malignancies Undergoing Radiotherapy | completed | — | 23 | West China HospitalOTHER | 1 | Apr 21, 2026 | clinicaltrials |
| NCT03881488 | Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies | completed | Phase 1 | 100 | Compass TherapeuticsINDUSTRY | 1 | Apr 17, 2026 | clinicaltrials |
| NCT03574792 | Gabapentin, Methadone, and Oxycodone With or Without Venlafaxine Hydrochloride in Managing Pain in Participants With Stage II-IV Squamous Cell Head and Neck Cancer Undergoing Chemoradiation Therapy | completed | Phase 2 | 62 | Roswell Park Cancer InstituteOTHER | 1 | Apr 16, 2026 | clinicaltrials |
| NCT04449445 | Perioperative Nutritional Optimization in Head and Neck Cancer Patients | completed | N/A | 4 | University of Illinois at ChicagoOTHER | 1 | Apr 14, 2026 | clinicaltrials |
| NCT04704453 | Study to Evaluate the Interest of Qutenza in Patients With Head and Neck Cancer in Remission and With Sequelae Neuropathic Pain.(TEC-ORL) | completed | Phase 2 | 13 | Institut Claudius RegaudOTHER | 1 | Apr 14, 2026 | clinicaltrials |
| NCT02649569 | Continuous Activity Monitoring During Fractionated Radiotherapy in Patients With Head and Neck, Lung, or Gastrointestinal Cancer | completed | — | 41 | Montefiore Medical CenterOTHER | 1 | Apr 13, 2026 | clinicaltrials |
| NCT03102229 | Real-time Activity Monitoring to Prevent Admissions During RadioTherapy(RAMPART) | completed | N/A | 40 | Montefiore Medical CenterOTHER | 1 | Apr 13, 2026 | clinicaltrials |
| NCT03115398 | A Simple Walking Program to Enhance Concurrent Chemoradiotherapy Delivery | completed | N/A | 166 | Montefiore Medical CenterOTHER | 1 | Apr 13, 2026 | clinicaltrials |
| NCT05461430 | Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)(TraveraRTGx) | completed | — | 72 | Travera IncINDUSTRY | 1 | Apr 13, 2026 | clinicaltrials |
| NCT06676943 | Investigating the Diagnostic Performance of High-resolution Specimen PET-CT in Determining Margin Status in Cancer Resection(eXcision) | completed | N/A | 57 | University Hospitals Coventry and Warwickshire NHS TrustOTHER | 1 | Apr 13, 2026 | clinicaltrials |
| NCT03236935 | Phase Ib of L-NMMA and Pembrolizumab | completed | Phase 1 | 12 | The Methodist Hospital Research InstituteOTHER | 1 | Apr 9, 2026 | clinicaltrials |
| NCT05077709 | IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC | completed | Phase 2 | 63 | IO BiotechINDUSTRY | 3 | Apr 8, 2026 | clinicaltrials |
| NCT05694819 | Darolutamide in Patients With Androgen Receptor-Positive Salivary Gland Carcinoma (DISCOVARY) | completed | Phase 2 | 57 | National Cancer Center Hospital EastOTHER | 1 | Apr 8, 2026 | clinicaltrials |
| NCT05563480 | TQB2618 Injection Combined With Penpulimab Injection in the Treatment of Patients With Recurrent/Metastatic Nasopharyngeal Carcinoma | completed | Phase 2 | 47 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | Apr 7, 2026 | clinicaltrials |
| NCT02510859 | Nutrition and Life QUality Patients With Head and Neck Cancers(NUQUE2) | completed | N/A | 117 | University Hospital, CaenOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT03370276 | Cetuximab & Nivolumab in Patients With Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma | completed | Phase 1 / Phase 2 | 95 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT05628883 | Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma | completed | Phase 1 | 17 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT05673577 | Camrelizumab in Combination With Cetuximab and Chemotherapy for Relapsed/Metastatic HNSCC Patients | completed | Phase 2 | 41 | Fudan UniversityOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT05315570 | Big Data for Quality of Life in Head and Neck Cancer(BD4QoL) | completed | N/A | 410 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 2 | Apr 1, 2026 | clinicaltrials |
| NCT05561920 | Phonatory Movement of the Pharyngoesophageal Mucosa in Laryngectomy Patients | completed | — | 55 | Osijek University HospitalOTHER | 1 | Mar 31, 2026 | clinicaltrials |
| NCT05696288 | Conventional Oxygen Therapy Versus Continuous Transnasal High Flow Oxygen Therapy for Head and Neck Diagnostic Panendoscopy Under General Anesthesia in Spontaneous Ventilation(OPTINOSE) | completed | N/A | 160 | Centre Antoine LacassagneOTHER | 1 | Mar 31, 2026 | clinicaltrials |
| NCT02517125 | Evaluation of the Contribution of Transoral Robotic-assisted Surgery Using Da Vinci Xi for Head and Neck Tumors(TORS) | completed | N/A | 100 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | Mar 30, 2026 | clinicaltrials |
| NCT01783587 | Safety Study of Afatinib and Postoperative Radiation Therapy to Treat Head and Neck Cancer | completed | Phase 1 | 29 | Dana-Farber Cancer InstituteOTHER | 1 | Mar 25, 2026 | clinicaltrials |
| NCT03217188 | Proton Re-Irradiation for Recurrent Head and Neck Cancer | completed | Phase 2 | 87 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 23, 2026 | clinicaltrials |
| NCT07488858 | Thyroidectomy: Microscopic Versus Conventional | completed | N/A | 74 | Shahida Islam Medical ComplexOTHER | 1 | Mar 23, 2026 | clinicaltrials |
| NCT04188665 | Using MASL to Combat Oral Cancer | completed | Early Phase 1 | 18 | Rowan UniversityOTHER | 1 | Mar 20, 2026 | clinicaltrials |
| NCT04251949 | Evaluation of the Photobiomodulation Using LED Lamp for Curative Treatment of Radio-induced Mucositis.(MuciLight) | completed | Phase 2 | 28 | Centre Oscar LambretOTHER | 1 | Mar 18, 2026 | clinicaltrials |
| NCT04883281 | A Prospective Study of Daily Adaptive Radiotherapy to Better Organ-at-Risk Doses in Head and Neck Cancer(DARTBOARD) | completed | Phase 2 | 50 | University of Texas Southwestern Medical CenterOTHER | 1 | Mar 18, 2026 | clinicaltrials |
| NCT01612351 | Multimodality Risk Adapted Tx Including Induction Chemo for SCCHN Amenable to Transoral Surgery | completed | Phase 2 | 40 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Mar 17, 2026 | clinicaltrials |
| NCT01647425 | Alcohol and Tobacco Consumption in Patients With Head and Neck or Lung Cancer(ALTAK) | completed | — | 385 | Centre Oscar LambretOTHER | 1 | Mar 16, 2026 | clinicaltrials |
| NCT04042935 | Alpha Lipoic Acid to Decrease Pain and Side Effects in Concurrent Treatment of HNSCC | completed | Phase 1 | 5 | University of Colorado, DenverOTHER | 1 | Mar 16, 2026 | clinicaltrials |
| NCT03313804 | Priming Immunotherapy in Advanced Disease With Radiation | completed | Phase 2 | 76 | John L. Villano, MD, PhDOTHER | 1 | Mar 11, 2026 | clinicaltrials |
| NCT04696744 | Prospective Study for the Prognostic and Predictive Role of Circulating Tumor Cells in Patients With Oropharyngeal Squamous Cell Carcinoma: CTCO (Circulating Tumor Cells in the Oropharynx)(CTCO) | completed | — | 12 | Hospices Civils de LyonOTHER | 1 | Mar 11, 2026 | clinicaltrials |
| NCT00939627 | Phase II Randomized Trial of the Combination of Cetuximab and Sorafenib or Single Agent Cetuximab | completed | Phase 2 | 55 | National Cancer Institute (NCI)NIH | 1 | Mar 10, 2026 | clinicaltrials |
| NCT05625217 | Total-Body FDG PET for Radiotherapy Response Assessment in Head and Neck Cancer | completed | N/A | 7 | University of California, DavisOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT02047474 | Combination Chemotherapy Before and After Surgery in Treating Patients With Localized Pancreatic Cancer | completed | Phase 2 | 46 | Yale UniversityOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT03431363 | Medical Cannabis During Chemoradiation for Head and Neck Cancer | completed | — | 30 | Albert Einstein College of MedicineOTHER | 1 | Mar 5, 2026 | clinicaltrials |
| NCT04610645 | Optical Coherence Tomography in Patients With Radiotherapy for Head and Neck Cancer(ROOCT) | completed | — | 30 | Krankenhaus Barmherzige Schwestern LinzOTHER | 1 | Mar 3, 2026 | clinicaltrials |
| NCT05389306 | Combining MRI and CEUS to Diagnose Small Cervical Lymph Node Metastases in NPC Patients(NPC-LN) | completed | N/A | 348 | Sun Yat-sen UniversityOTHER | 1 | Mar 3, 2026 | clinicaltrials |
| NCT07431645 | Pilot Study of Radiation-Induced Xerostomia Treatment With Allogeneic Mesenchymal Stromal Stem Cells | completed | Phase 1 | 10 | Institute of Oncology LjubljanaOTHER | 1 | Mar 3, 2026 | clinicaltrials |
| NCT02031250 | Randomized Phase II Study of DCE-MRI-based Dose Escalation for Poor-prognosis and Neck Cancer | completed | Phase 2 | 106 | University of Michigan Rogel Cancer CenterOTHER | 1 | Mar 2, 2026 | clinicaltrials |
| NCT00003809 | Cisplatin With or Without Monoclonal Antibody Therapy in Treating Patients With Metastatic or Recurrent Head and Neck Cancer | completed | Phase 3 | — | Eastern Cooperative Oncology GroupNETWORK | 3 | Feb 27, 2026 | clinicaltrials |
| NCT02589938 | Trial of Acupuncture for Radiation-Induced Xerostomia in Head and Neck Cancer(ACUPUNCTURE) | completed | N/A | 258 | Wake Forest University Health SciencesOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT05115825 | Pain Management for Head and Neck Cancer Survivors | completed | N/A | 33 | OHSU Knight Cancer InstituteOTHER | 1 | Feb 27, 2026 | clinicaltrials |
| NCT07434245 | İnvestigation of the Effect of Neck Endurance on Swallowing and Directional Coordination in Head and Neck Cancer Patients | completed | — | 28 | Istanbul Arel UniversityOTHER | 1 | Feb 25, 2026 | clinicaltrials |
| NCT07419113 | Development of an Integrated Multi-channel Artificial Nose for Cancer Detection (UNos)(UNOS) | completed | N/A | 45 | Institute of Oncology LjubljanaOTHER | 1 | Feb 24, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Apr 22, 2026source: clinicaltrials