Clinical trial · Interventional
Thyroidectomy: Microscopic Versus Conventional
Comparison of Outcomes of Microscopic Versus Conventional Thyroidectomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Despite promising findings from international studies, the use of microscopic thyroidectomy remains limited in local surgical practice, where conventional thyroidectomy is traditionally followed. There is a scarcity of local data evaluating the benefits of MT, and inconsistencies in reported outcomes highlight the need for further research. The lack of standardized protocols and limited surgeon experience with microscopic techniques contribute to hesitation in its adoption. This study aims to address the research gap by providing comparative data on operative time, intraoperative blood loss, and postoperative complications in microscopic versus conventional thyroidectomy in our setting. The findings will aid in determining whether MT should be incorporated into routine surgical practice to improve patient outcomes and reduce postoperative complications.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Cancer | Malignant Thyroid Gland Neoplasm | CURATED_EXACT | 0.92 |
| Thyroid Surgeries | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conventional Thyroidectomy | Procedure | — | UNRESOLVED |
| Microscopic Thyroidectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Microscopic Thyroidectomy
- interventionNames
- Procedure: Microscopic Thyroidectomy
- type
- PLACEBO_COMPARATOR
- label
- Conventional Thyroidectomy
- interventionNames
- Procedure: Conventional Thyroidectomy
Primary outcomes (4)
- measure
- Mean intraoperative blood loss
- timeFrame
- 0 days
- description
- It will be defined as the mean total volume of blood lost during the surgical procedure, measured in milliliters (mL). Blood loss will be estimated using the difference between preoperative and postoperative suction canister volumes, accounting for irrigation fluids, and by weighing surgical sponges and gauze (1 g of blood = 1 mL).
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Both Male or female patients. * Patients aged 18 to 65 years undergoing thyroidectomy for benign or malignant thyroid disease. * Patients with multinodular goiter, Grave's disease, thyroid carcinoma indicated for surgery based on their workup. * Candidates scheduled for unilateral lobectomy, subtotal thyroidectomy, or total thyroidectomy. * Patients with preoperative normal vocal cord mobility confirmed by laryngoscopy. Hemodynamically stable patients without significant comorbidities affecting surgery or anesthesia based on ASA classification (Class I-III). • Patients who provide informed consent to participate in the study. Exclusion Criteria: • Prior history of prior thyroid surgery. * Patients with evidence of lateral lymph node metastasis or local invasion on preoperative imaging (ultrasonography or computed tomography). * Patients with pre-existing hypocalcemia or parathyroid disorders. * Patients with severe medical comorbidities, including uncontrolled diabetes (HbA1c \> 8%), chronic kidney disease (eGFR \< 30 mL/min/1.73m²), liver cirrhosis (Child-Pugh class B or C), or coagulopathy (INR \> 1.5 or platelet count \< 50,000/μL), will be excluded from the study. * Pregnant or lactating women. * Patients with invasive thyroid carcinoma, anaplastic thyroid carcinoma, or thyroid lymphoma requiring extensive radical surgery.
References
Publications (0)
Data not yet available