Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
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Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05504265 | Perioperative Analgesia Modes in Minimally Invasive Esophagectomy | unknown | Phase 2 / Phase 3 | 102 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Mar 20, 2025 | clinicaltrials |
| NCT02509286 | Perioperative Chemotherapy Compared To Neoadjuvant Chemoradiation in Patients With Adenocarcinoma of the Esophagus(ESOPEC) | unknown | Phase 3 | 438 | University Hospital Schleswig-HolsteinOTHER | 1 |
| May 8, 2024 |
| clinicaltrials |
| NCT02556762 | Simultaneous Modulated Accelerated Boost Versus Standard Dose Radiotherapy in Esophageal Cancer(SUMC-EC-002) | unknown | Phase 3 | 202 | Chuangzhen ChenOTHER | 1 | Feb 6, 2024 | clinicaltrials |
| NCT05737563 | PD-1 Antibody Combined With mXELIRI Versus mXELIRI in the Second-line Setting for ESCC(Escape) | unknown | Phase 3 | 380 | Sun Yat-sen UniversityOTHER | 1 | Jan 23, 2024 | clinicaltrials |
| NCT02465736 | Study of Docetaxel or Vinorelbine Plus Cisplatin in Neoadjuvant Chemoradiotherapy for Esophageal Cancer (NEOCRTEC308) | unknown | Phase 3 | 610 | Sun Yat-sen UniversityOTHER | 1 | Jan 16, 2024 | clinicaltrials |
| NCT03790553 | Comparing 61.2 Gy Radiotherapy Dose Versus 50.4 Gy Radiotherapy Dose for Locally Advanced Esophageal Carcinoma | unknown | Phase 3 | 646 | Fudan UniversityOTHER | 1 | Aug 3, 2023 | clinicaltrials |
| NCT03958890 | A Clinical Trial Comparing HLX10 With Placebo Combined With Chemotherapy (Cisplatin + 5-fu) in the First-line Treatment of Locally Advanced/Metastatic Esophageal Squamous Cell Carcinoma (ESCC) | unknown | Phase 3 | 489 | Shanghai Henlius BiotechINDUSTRY | 1 | Apr 18, 2023 | clinicaltrials |
| NCT05817201 | Toripalimab Plus Radiotherapy for Elderly Esophageal Cancer Patients Treated With Non-chemotherapy Strategy | unknown | Phase 2 / Phase 3 | 60 | Taizhou HospitalOTHER | 1 | Apr 18, 2023 | clinicaltrials |
| NCT02025036 | Chemoradiotherapy of Capecitabine With or Without Oxaliplatin Versus Cisplatin-5-FU for Esophageal Squamous Cancer(CRTCOESC) | unknown | Phase 3 | 249 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Feb 8, 2023 | clinicaltrials |
| NCT05213312 | Study of Neoadjuvant Nivolumab or Placebo Plus Chemotherapy Followed by Surgery and Adjuvant Treatment in Subjects With Resectable ESCC | unknown | Phase 2 / Phase 3 | 90 | Shanghai Zhongshan HospitalOTHER | 1 | Jun 15, 2022 | clinicaltrials |
| NCT03623737 | Comparing Paclitaxel/Cisplatin and Cisplatin/5-fluorouracil in Neo-CRT for ESCC | unknown | Phase 2 / Phase 3 | 248 | National Taiwan University HospitalOTHER | 1 | Jun 7, 2022 | clinicaltrials |
| NCT05049681 | Study of Anti-PD-1 Antibody SHR-1210 Plus Apatinib vs SHR-1210 as Second-Line Treatment of Advanced Esophageal Squamous Cell | unknown | Phase 3 | 234 | Feng WangOTHER | 0 | Sep 20, 2021 | clinicaltrials |
| NCT04426955 | Study of Camrelizumab (SHR-1210) in Combination With Concurrent Chemoradiotherapy in Locally Advanced Esophageal Cancer | unknown | Phase 3 | 396 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Sep 16, 2021 | clinicaltrials |
| NCT02279134 | Phase II/III Study Compare Adjuvant Chemoradiotherapy, Radiotherapy and Surgery Alone for Esophageal Carcinoma | unknown | Phase 2 / Phase 3 | 360 | Zefen XiaoUNKNOWN | 1 | Apr 3, 2020 | clinicaltrials |
| NCT03094351 | Robot-assisted Esophagectomy Versus Conventional Thoracoscopic Esophagectomy(RAE vs CTE) | unknown | Phase 3 | 360 | Shanghai Chest HospitalOTHER | 1 | Feb 5, 2020 | clinicaltrials |
| NCT03708042 | A Study to Compare Efficacy and Safety of DRT VS CRT Plus Surgery in Patients Who Achieved CCR for Esophageal Cancer | unknown | Phase 3 | 220 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Oct 16, 2018 | clinicaltrials |
| NCT03366883 | Paclitaxel, Cisplatin,5-FU vs. Radiotherapy Plus Paclitaxel, Cisplatin as Preoperative Therapy for Locally Advanced ESC | unknown | Phase 3 | 420 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jan 9, 2018 | clinicaltrials |
| NCT03273647 | Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma With Positive Circumstantial Resection Margin | unknown | Phase 3 | 60 | Fudan UniversityOTHER | 0 | Oct 19, 2017 | clinicaltrials |
| NCT03273686 | Efficacy of Nasogastric Tube Application in Postoperative Care of Esophagectomy | unknown | Phase 3 | 100 | Fudan UniversityOTHER | 0 | Sep 6, 2017 | clinicaltrials |
| NCT01216527 | Phase III Study of Neo-adjuvant Chemoradiotherapy Followed by Surgery for Squamous Cell Esophageal Cancer | unknown | Phase 3 | 430 | Sun Yat-sen UniversityOTHER | 1 | Feb 27, 2017 | clinicaltrials |
| NCT02604615 | The Role of Different Cycles of Chemotherapy（Capecitabine-oxaliplatin） in Esophageal Chemoradiotherapy(DCOECRT) | unknown | Phase 3 | 60 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Jul 6, 2016 | clinicaltrials |
| NCT02677597 | Cisplatin Combined With S-1 or Paclitaxel as First-line Treatment for Metastatic Esophageal Squamous Cell Carcinoma | unknown | Phase 3 | 268 | Fudan UniversityOTHER | 1 | Feb 9, 2016 | clinicaltrials |
| NCT02611700 | Nimotuzumab in Combined With Paclitaxel and Cisplatin for Treatment of Metastatic Esophageal Squamous Cell Carcinoma | unknown | Phase 3 | 504 | Biotech Pharmaceutical Co., Ltd.OTHER | 1 | Feb 1, 2016 | clinicaltrials |
| NCT02607540 | Different Cycles of Cisplatin-5-fluorouracil for the Chemoradiotherapy of Esophageal Squamous Cancer(PFCRTESC) | unknown | Phase 3 | 210 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Jan 12, 2016 | clinicaltrials |
| NCT01242124 | Impact of the Techniques for Intrathoracic Esophagogastric Anastomosis on Outcome in Ivor-Lewis Oesophagectomy | unknown | Phase 2 / Phase 3 | 40 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Dec 22, 2015 | clinicaltrials |
| NCT02628665 | Clinical Study of Time Optimizing of Endoscopic Photodynamic Therapy on Esophageal and/or Gastric Cardiac Cancer | unknown | Phase 3 | 40 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Dec 11, 2015 | clinicaltrials |
| NCT02603159 | Different Cycles of Capecitabine Usage in Esophageal Cancer Concurrent Chemoradiotherapy(DCECRT) | unknown | Phase 3 | 200 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Nov 11, 2015 | clinicaltrials |
| NCT02570893 | A Phase III Trail of Adjuvant Chemoradiotherapy Versus Adjuvant Radiotherapy in Esophageal Squamous Cell Carcinoma | unknown | Phase 3 | 366 | Zhejiang Cancer HospitalOTHER | 1 | Oct 7, 2015 | clinicaltrials |
| NCT02461043 | Adjuvant Chemotherapy With Paclitaxel and Cisplatin in Lymph Node-Positive Adjuvant Chemotherapy in the Treatment of the Lymph Node Positive Thoracic Esophageal Squamous Cell Carcinoma | unknown | Phase 3 | 386 | Chinese Academy of Medical SciencesOTHER | 1 | Sep 1, 2015 | clinicaltrials |
| NCT02448979 | Esophagectomy in Middle and Lower Thoracic Esophageal Cancer Patients Through Left Versus Right Transthoracic Approach | unknown | Phase 3 | 800 | Chinese Academy of Medical SciencesOTHER | 1 | May 20, 2015 | clinicaltrials |
| NCT02355249 | Traditional Three Incisions vs Minimally Invasive Thoracol-laparoscopic Esophagectomy for Esophageal Cancer | unknown | Phase 3 | 648 | Chinese Academy of Medical SciencesOTHER | 1 | Feb 4, 2015 | clinicaltrials |
| NCT00686114 | Concurrent Chemoradiotherapy Containing Paclitaxel&Cisplatin With/Without Tarceva in Locally Advanced Esophageal Cancer | unknown | Phase 3 | 344 | Wenzhou Medical UniversityOTHER | 1 | Apr 29, 2014 | clinicaltrials |
| NCT01937208 | Comparable Study of Different Radiation Dose in Esophageal Carcinoma | unknown | Phase 3 | 300 | Zhejiang Cancer HospitalOTHER | 1 | Sep 9, 2013 | clinicaltrials |
| NCT00041262 | Combination Chemotherapy in Treating Patients With Esophageal Cancer | unknown | Phase 3 | 1,300 | Medical Research CouncilOTHER_GOV | 1 | Aug 12, 2013 | clinicaltrials |
| NCT00002884 | Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Esophagus | unknown | Phase 3 | 326 | Centre Hospitalier Lyon SudOTHER | 1 | Aug 7, 2013 | clinicaltrials |
| NCT00509561 | Cisplatin, Capecitabine, and Radiation Therapy With or Without Cetuximab in Treating Patients With Esophageal Cancer | unknown | Phase 2 / Phase 3 | 259 | Wales Cancer Trials UnitOTHER | 1 | Dec 18, 2012 | clinicaltrials |
| NCT01054274 | a Multicentric Randomized Controlled Trial of Self-Expandable Esophageal Radiation Stent | unknown | Phase 3 | 180 | Southeast University, ChinaOTHER | 1 | Apr 2, 2012 | clinicaltrials |
| NCT01402180 | Chemoradiation With or Without Nimotuzumab in Treating Esophageal Cancer Patients Who Suffer With Recurrence in Regional Lymph Nodes After Esophagectomy(Nimotuzumab) | unknown | Phase 2 / Phase 3 | 128 | Fudan UniversityOTHER | 1 | Jul 26, 2011 | clinicaltrials |
| NCT01398449 | Is ENI Necessary For Patients With Thoracic Esophageal Cancer After Esophagectomy And With Pathological Stage Of T1-2,N+,M0 | unknown | Phase 3 | 874 | Fudan UniversityOTHER | 1 | Jul 20, 2011 | clinicaltrials |
| NCT01053182 | Esophagectomy Associated Respiratory Complications: Ivor-Lewis Versus Sweet Approaches | unknown | Phase 3 | 320 | Sichuan UniversityOTHER | 1 | Jan 21, 2010 | clinicaltrials |
| NCT01034683 | Study of Lobaplatin，5-Fluorouracil and Leucovorin for the Treatment of Esophageal Carcinoma | unknown | Phase 3 | 120 | Taian Cancer HospitalOTHER | 1 | Jan 5, 2010 | clinicaltrials |
| NCT00193817 | Three Field Radical Esophagectomy Versus Two Field Esophagectomy - a Prospective Trial | unknown | Phase 3 | 700 | Tata Memorial HospitalOTHER_GOV | 1 | Feb 7, 2006 | clinicaltrials |
Data updated 22 days agoSource updated Mar 20, 2025source: clinicaltrials