Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
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Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00052910 | Chemotherapy and Radiation Therapy After Surgery in Treating Patients With Stomach or Esophageal Cancer | completed | Phase 3 | 546 | Alliance for Clinical Trials in OncologyOTHER | 2 | May 7, 2020 | clinicaltrials |
| NCT00901173 | A Pilot for a Case-Control Study of Esophageal Squamous Cell Carcinoma in Western Kenya | completed | — | 372 | National Cancer Institute (NCI)NIH | 1 | Apr 24, 2020 |
| NCT00047112 | Surgery With or Without Radiation Therapy and Chemotherapy in Treating Patients With Esophageal Cancer | completed | Phase 3 | 195 | Federation Francophone de Cancerologie DigestiveOTHER | 4 | Mar 30, 2020 | clinicaltrials |
| NCT01544790 | Robot-assisted Thoraco-laparoscopic Esophagectomy Versus Open Transthoracic Esophagectomy(ROBOT) | completed | Phase 3 | 112 | UMC UtrechtOTHER | 1 | Mar 26, 2020 | clinicaltrials |
| NCT03061370 | Sarcopenia and Visceral Obesity in Esophageal and Gastric Cancer | completed | — | 317 | St. James's Hospital, IrelandOTHER | 1 | Mar 26, 2020 | clinicaltrials |
| NCT03461341 | European iNvestigation of SUrveillance After Resection for Esophageal Cancer(ENSURE) | completed | — | 3,000 | St. James's Hospital, IrelandOTHER | 3 | Mar 26, 2020 | clinicaltrials |
| NCT02399306 | Chemoradiotherapy With or Without Enteral Nutrition for Locally Advanced Thoracic Esophageal Carcinoma | completed | Phase 3 | 222 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Mar 17, 2020 | clinicaltrials |
| NCT01787006 | Definitive Radiochemotherapy Plus/Minus Cetuximab in Unresectable Locally Advanced Esophageal Cancer | completed | Phase 2 | 74 | University Hospital Schleswig-HolsteinOTHER | 1 | Mar 10, 2020 | clinicaltrials |
| NCT03515356 | Exercise to Reduce Chemotherapy-Induced Peripheral Neuropathy | completed | N/A | 54 | University of Michigan Rogel Cancer CenterOTHER | 1 | Mar 9, 2020 | clinicaltrials |
| NCT02946671 | Study of Pre-operative Combination Therapy With Mogamulizumab and Nivolumab Against Solid Cancer Patients | completed | Phase 1 | 16 | Osaka UniversityOTHER | 1 | Mar 6, 2020 | clinicaltrials |
| NCT03526328 | DCLK1 as a Marker/Indicator of Stem Cell Response in Barrett's Esophagus/Esophageal Adenocarcinoma | completed | — | 32 | University of OklahomaOTHER | 1 | Mar 6, 2020 | clinicaltrials |
| NCT01362127 | Neoadjuvant Chemotherapy Versus Radiochemotherapy for Cancer of the Esophagus or Cardia(NeoRes) | completed | Phase 2 | 181 | Karolinska University HospitalOTHER | 1 | Feb 26, 2020 | clinicaltrials |
| NCT00439608 | Cetuximab, Paclitaxel, Carboplatin & Radiation for Esoph, Gastroesoph & Gastric Cancer | completed | Phase 2 | 60 | Brown UniversityOTHER | 1 | Feb 17, 2020 | clinicaltrials |
| NCT00522795 | Neoadjuvant Paclitaxel Poliglumex, Cisplatin and Radiation for Esophageal Cancer: A Phase II Trial (CTI#X64001) | completed | Phase 2 | 40 | Brown UniversityOTHER | 1 | Feb 17, 2020 | clinicaltrials |
| NCT01747551 | FOLFOX +/- Ziv-Aflibercept for Esophageal and Gastric Cancer | completed | Phase 2 | 64 | Dana-Farber Cancer InstituteOTHER | 1 | Feb 10, 2020 | clinicaltrials |
| NCT01348217 | Radiochemotherapy With and Without Dose Escalation in Patients Presenting Locally Advanced or Inoperable Carcinoma of the Oesophagus(CONCORDE) | completed | Phase 2 / Phase 3 | 196 | Centre Georges Francois LeclercOTHER | 1 | Jan 27, 2020 | clinicaltrials |
| NCT03159585 | To Evaluate the Efficacy of NY-ESO-1-specific T Cell Receptor Affinity Enhancing Specific T Cell in Solid Tumors | completed | Phase 1 | 6 | Zhujiang HospitalOTHER | 1 | Jan 22, 2020 | clinicaltrials |
| NCT04219410 | Assessment of a Modified Minimally Invasive Esophagectomy | completed | — | 142 | Kaiser PermanenteOTHER | 0 | Jan 7, 2020 | clinicaltrials |
| NCT03222440 | Combination of Radiotherapy and SHR-1210 to Treat Patients With ESCC | completed | N/A | 20 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Dec 4, 2019 | clinicaltrials |
| NCT02347904 | Feasibility Study of Adjuvant Treatment With S-1 and Oxaliplatin in Patients With Resectable Esophageal Cancer(SOX) | completed | Phase 1 | 40 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Nov 18, 2019 | clinicaltrials |
| NCT01498289 | S1201: Combination Chemo for Patients W/Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Cancer | completed | Phase 2 | 213 | SWOG Cancer Research NetworkNETWORK | 1 | Nov 7, 2019 | clinicaltrials |
| NCT02829489 | International Nutrition Audit in FORegut TuMors(INFORM) | completed | — | 170 | University of AlbertaOTHER | 5 | Nov 5, 2019 | clinicaltrials |
| NCT01661686 | Fully Covered or Partially Covered Stents in Malignant Esophageal Strictures(COPAC) | completed | N/A | 98 | Foundation for Liver ResearchOTHER | 1 | Oct 3, 2019 | clinicaltrials |
| NCT02574663 | TGR-1202 Alone and in Combination With Either Nab-paclitaxel + Gemcitabine or With FOLFOX in Patients With Select Relapsed or Refractory Solid Tumors | completed | Phase 1 | 66 | TG Therapeutics, Inc.INDUSTRY | 1 | Oct 2, 2019 | clinicaltrials |
| NCT00037817 | Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion With or Without Concurrent Celecoxib in Subjects With Pulmonary and Pleural Malignancies | completed | Phase 1 | 34 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2019 | clinicaltrials |
| NCT03457506 | Intra-individual Comparison of Conventional and Digital PET/CT Scanners | completed | N/A | 225 | IsalaOTHER | 1 | Sep 19, 2019 | clinicaltrials |
| NCT01059643 | A Study in Ovarian, Non-Small Cell Lung, Prostate, Colorectal, Gastroesophageal Cancers, and Squamous Cell Carcinoma of the Head and Neck | completed | Phase 2 | 103 | Eli Lilly and CompanyINDUSTRY | 1 | Sep 18, 2019 | clinicaltrials |
| NCT02843581 | Combination of Cryosurgery and NK Immunotherapy for Advanced Esophageal Cancer | completed | Phase 1 / Phase 2 | 60 | Fuda Cancer Hospital, GuangzhouOTHER | 1 | Sep 12, 2019 | clinicaltrials |
| NCT02389751 | Ganetespib in Combination With Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Stage II-III Esophageal Cancer | completed | Phase 1 | 3 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 24, 2019 | clinicaltrials |
| NCT01855854 | Second-line Treatment With Icotinib in Esophageal Carcinoma Patients With EGFR Overexpression (IHC 3+) or Positive FISH | completed | Phase 2 | 54 | Betta Pharmaceuticals Co., Ltd.INDUSTRY | 1 | Jul 5, 2019 | clinicaltrials |
| NCT02139488 | Organ Motion and Early Tumor Response Measurement | completed | — | 80 | The Netherlands Cancer InstituteOTHER | 1 | Jun 27, 2019 | clinicaltrials |
| NCT03081715 | PD-1 Knockout Engineered T Cells for Advanced Esophageal Cancer | completed | N/A | 16 | Hangzhou Cancer HospitalOTHER | 1 | Jun 12, 2019 | clinicaltrials |
| NCT02649361 | Study of Anlotinib in Patients With Esophageal Squamous Cell Carcinoma (ALTER1102) | completed | Phase 2 | 164 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | Jun 5, 2019 | clinicaltrials |
| NCT03584308 | Efficacy of VIUSID® Plus GLIZIGEN® in Patients With Papilloma Virus Esophageal | completed | Phase 2 | 110 | Catalysis SLINDUSTRY | 1 | May 22, 2019 | clinicaltrials |
| NCT02803281 | Assessment of Patient Frailty Prior to Thoracic Surgery | completed | — | 40 | University Health Network, TorontoOTHER | 1 | May 7, 2019 | clinicaltrials |
| NCT00601705 | Epirubicin, Oxaliplatin and Fluorouracil (EOF) in Cancer of the Esophagus, Gastroesophageal Junction, or Stomach | completed | Phase 2 | 61 | Case Comprehensive Cancer CenterOTHER | 1 | Apr 30, 2019 | clinicaltrials |
| NCT03113214 | PET/CT-directed Hyperfractionated Radiation Dose Escalation in Esophageal Cancer | completed | N/A | 27 | Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 1 | Apr 5, 2019 | clinicaltrials |
| NCT00917462 | Sorafenib for Patients With Metastatic or Recurrent Esophageal and Gastroesophageal Junction Cancer | completed | Phase 2 | 35 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 27, 2019 | clinicaltrials |
| NCT00217581 | Bevacizumab, Oxaliplatin, and Docetaxel in Treating Patients With Locally Advanced Unresectable or Metastatic Stomach or Gastroesophageal Junction Cancer | completed | Phase 2 | 39 | Barbara Ann Karmanos Cancer InstituteOTHER | 1 | Mar 26, 2019 | clinicaltrials |
| NCT01490749 | Trial of XELOX Followed by Radiation Combined With Carboplatin and RAD001 for Esophageal Cancer | completed | Phase 1 | 17 | Emory UniversityOTHER | 1 | Mar 15, 2019 | clinicaltrials |
| NCT01715233 | Phase II Study Using CHFR Methylation Status in Patients With Metastatic Esophageal, Gastroesophageal, Gastric Cancer. | completed | Phase 2 | 27 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Mar 15, 2019 | clinicaltrials |
| NCT03671642 | Perioperative Perfusion Measurement - a Feasibility and Usability Study | completed | N/A | 10 | Rigshospitalet, DenmarkOTHER | 1 | Mar 12, 2019 | clinicaltrials |
| NCT01831531 | Study of S-1 in Combination With Radiotherapy in Esophageal Cancer | completed | Phase 2 | 105 | Fudan UniversityOTHER | 1 | Feb 15, 2019 | clinicaltrials |
| NCT03787537 | Nutritional Status and Nutrient Supply in Hospitalised Surgical Patients | completed | — | 128 | Charite University, Berlin, GermanyOTHER | 1 | Jan 31, 2019 | clinicaltrials |
| NCT01386346 | Epigenetic Priming Using Azacitidine With Neoadjuvant Chemotherapy for Resectable Esophageal Cancer(VEOX) | completed | Phase 1 | 12 | Weill Medical College of Cornell UniversityOTHER | 1 | Dec 12, 2018 | clinicaltrials |
| NCT02960594 | hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse(TRT-001) | completed | Phase 1 | 93 | Inovio PharmaceuticalsINDUSTRY | 1 | Nov 19, 2018 | clinicaltrials |
| NCT03292757 | FLOTOR Pilot Study(FLOTOR) | completed | Phase 1 / Phase 2 | 21 | Oxford University Hospitals NHS TrustOTHER | 1 | Nov 19, 2018 | clinicaltrials |
| NCT01262040 | Narrow Band Imaging (NBI): A Novel Imaging Modality in Minimally Invasive | completed | N/A | 154 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Nov 7, 2018 | clinicaltrials |
| NCT00215644 | Matuzumab Treatment With Epirubicin, Cisplatin and Capecitabine (ECX) in Esophago-Gastric Cancer(MATRIX EG) | completed | Phase 2 | 72 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 4 | Nov 2, 2018 | clinicaltrials |
| NCT00137813 | Avastin and Taxotere for Esophagogastric Cancer | completed | Phase 2 | 42 | Dana-Farber Cancer InstituteOTHER | 1 | Nov 1, 2018 | clinicaltrials |
Data updated 23 days agoSource updated May 7, 2020source: clinicaltrials