Clinical trial · Interventional
Intra-individual Comparison of Conventional and Digital PET/CT Scanners
Intra-individual Patient-based Comparison of Conventional and Digital PET/CT Scanners
NCT03457506CI-TRIAL-00040711completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In this study, the investigators will analyze the impact of digital PET/CT on the final diagnostic conclusion of the scan in patients with lung cancer, breast cancer, esophageal cancer and a group of mescellaneous cancers.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Miscellaneous Neoplasm | Miscellaneous Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Digital PET/CT scan | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Patients undergo a digital PET/CT
- description
- Single arm prospective study of paired PET scans. Patients who are referred to the nuclear medicine department to undergo a PET scan, will undergo a PET/CT scan on the conventional scanner as well as the digital PET/CT scanner.
- interventionNames
- Diagnostic Test: Digital PET/CT scan
Primary outcomes (1)
- measure
- Diagnostic outcome of the PET/CT study
- timeFrame
- approximately 2 hours
Secondary outcomes (1)
- measure
- PET image quality
- timeFrame
- approximately 2 hours
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion criteria In order to be eligible to participate in this study, a subject must meet all of the following criteria: * referred to Isala for a clinically indicated FDG-PET/CT scan * suspected or proven lung cancer, esophageal cancer, breast cancer or miscellaneous cancer, either as a primary diagnosis or follow-up study * signed informed consent Exclusion criteria A potential subject who meets any of the following criteria will be excluded from participation in this study: * age \< 18 years * incapacitated adults * prisoners * pregnant patients * unable to undergo two consecutive PET/CT scans
References
Publications (1)
- DERIVEDKoopman D, Jager PL, Slump CH, Knollema S, van Dalen JA. SUV variability in EARL-accredited conventional and digital PET. EJNMMI Res. 2019 Dec 10;9(1):106. doi: 10.1186/s13550-019-0569-7. PMID 31823097