Exercise to Reduce Chemotherapy-Induced Peripheral Neuropathy

Inclusion Criteria:

* Diagnosed GI cancer (e.g, colorectal, gastric, pancreatic, esophageal, bowel);
* Scheduled to receive at least 6 cycles of oxaliplatin (85 mg/m2);
* Receiving care at the University of Michigan or St. Joseph Cancer Clinics;
* A Karnofsky Performance Status ≥ 80% or an Eastern Cooperative Oncology Group Status 0 to 1;
* Voluntarily consented to participate in all intervention components.

Exclusion Criteria:

* Exercise- or mobility-limiting cardiovascular, pulmonary, musculoskeletal, or psychological disease, based on the EMR (electronic medical record) past medical history and consultation with the medical oncologist;
* Scheduled major surgery during the study time period;
* Pre-existing peripheral neuropathy prior to chemotherapy (potentially due to diabetes, central nervous system malignancy, vitamin deficiency, heredity, nerve compression injury, non-surgically corrected carpal tunnel disease, or alcohol dependence) per patient self-report in response to brief screening questions noted in the pre-screening section;
* Pregnancy;
* Inability to read or speak English;
* Prognosis of less than three months.