Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
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Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03910634 | IMRT With Carboplatin Versus IMRT With Carboplatin and Fluorouracil for Eldly Esophageal Cancer Patients | unknown | Phase 2 | 264 | Sun Yat-sen UniversityOTHER | 1 | Apr 10, 2019 | clinicaltrials |
| NCT02812641 | Neoadjuvant CCRT With/Without Bevacizumab for Locally Advanced ESCC | unknown | Phase 2 | 50 | National Taiwan University HospitalOTHER | 1 | Mar 11, 2019 | clinicaltrials |
| NCT03857763 |
| A Prospective Study of Apatinib Plus Concurrent Neoadjuvant Chemoradiotherapy in Patients With Esophageal Squamous Cell Carcinoma |
| unknown |
| Phase 2 |
| 40 |
| Hebei Medical University Fourth HospitalOTHER |
| 0 |
| Feb 28, 2019 |
| clinicaltrials |
| NCT03833466 | Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo)(ECMTPneo) | unknown | Phase 2 | 15 | Peking UniversityOTHER | 1 | Feb 15, 2019 | clinicaltrials |
| NCT02353936 | A Phase II Trial of Afatinib in Patients With Metastatic or Recurrent Squamous Cell Carcinoma of Esophagus | unknown | Phase 2 | 30 | Yonsei UniversityOTHER | 1 | Feb 11, 2019 | clinicaltrials |
| NCT03817567 | Safety and Efficacy of SCT200 in Patients With Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 1 / Phase 2 | 50 | Sinocelltech Ltd.INDUSTRY | 1 | Jan 25, 2019 | clinicaltrials |
| NCT03817658 | A Phase II Study of SHR-1210 vs Placebo as Consolidation Chemotherapy After Radical Concurrent Chemoradiotherapy in Locally Advanced ESCC | unknown | Phase 2 | 725 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Jan 25, 2019 | clinicaltrials |
| NCT03811379 | Toripalimab as Monotherapy for Patients With Small Cell Carcinoma of Esophagus Who Failed Chemotherapy | unknown | Phase 2 | 43 | Sun Yat-sen UniversityOTHER | 1 | Jan 23, 2019 | clinicaltrials |
| NCT03804203 | Short Course Radiation Therapy in Palliative Treatment of Esophageal Cancer | unknown | N/A | 98 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 1 | Jan 15, 2019 | clinicaltrials |
| NCT03671265 | Combination of Chemotherapy Plus RT and SHR-1210 to Treat Patients With ESCC | unknown | N/A | 20 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jan 9, 2019 | clinicaltrials |
| NCT03757754 | HPPH Photodynamic Therapy for Patients With Esophageal Cancer(HPPH) | unknown | Phase 1 | 30 | Zhejiang Hisun Pharmaceutical Co. Ltd.INDUSTRY | 1 | Nov 29, 2018 | clinicaltrials |
| NCT03732508 | SHR-1316 in Combination With Chemotherapy in Patients With Esophageal Squamous Cell Cancer | unknown | Phase 2 | 30 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Nov 6, 2018 | clinicaltrials |
| NCT03274349 | Whole Body Electromyostimulation and Nutritional Therapy for Patients With Esophageal and Bronchial Carcinoma | unknown | N/A | 150 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Oct 16, 2018 | clinicaltrials |
| NCT03706326 | CAR T and PD-1 Knockout Engineered T Cells for Esophageal Cancer | unknown | Phase 1 / Phase 2 | 20 | The First Affiliated Hospital of Guangdong Pharmaceutical UniversityOTHER | 1 | Oct 16, 2018 | clinicaltrials |
| NCT03708042 | A Study to Compare Efficacy and Safety of DRT VS CRT Plus Surgery in Patients Who Achieved CCR for Esophageal Cancer | unknown | Phase 3 | 220 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Oct 16, 2018 | clinicaltrials |
| NCT03213054 | A Study of OBP-301 With Radiation Therapy in Patients With Esophageal Cancer | unknown | Phase 1 | 12 | Oncolys BioPharma IncINDUSTRY | 1 | Sep 26, 2018 | clinicaltrials |
| NCT03668418 | Xenotransplantation of Primary Cancer Samples in Zebrafish Embryos(xenoZ) | unknown | — | 120 | University of PisaOTHER | 1 | Sep 12, 2018 | clinicaltrials |
| NCT03642093 | HOPE - A Study to Evaluate the Effect of a Prehabilitation Program on GI Cancer Patients Planning to Undergo Surgery(HOPE) | unknown | Phase 4 | 60 | Siobhan TrotterOTHER | 1 | Sep 11, 2018 | clinicaltrials |
| NCT03649945 | Endostatin Combined With Chemotherapy for Adjuvant Treatment of Esophageal Cancer | unknown | Phase 2 | 186 | First Affiliated Hospital of Guangxi Medical UniversityOTHER | 0 | Aug 28, 2018 | clinicaltrials |
| NCT03585673 | Docetaxel-polymeric Micelles(PM) and Oxaliplatin for Esophageal Carcinoma(DOSE) | unknown | Phase 2 | 38 | Sung Yong OhOTHER | 1 | Jul 17, 2018 | clinicaltrials |
| NCT01807390 | Perspectives of Receiving Open Versus Minimally Invasive Surgery(PROMIS) | unknown | — | 200 | Ottawa Hospital Research InstituteOTHER | 1 | Apr 17, 2018 | clinicaltrials |
| NCT03492827 | Evaluation of the Preventive Effect of Chlorhexidine Acetate Gargle for Upper Gastrointestinal Tract Infection After ESD | unknown | N/A | 306 | Peking University Third HospitalOTHER | 1 | Apr 10, 2018 | clinicaltrials |
| NCT02924909 | Phase II Trial of Neoadjuvant Treatment and Minimal Invasive Surgery for Esophageal and GEJ Cancer(QUIMERA) | unknown | Phase 2 | 50 | Instituto Nacional de Cancer, BrazilOTHER_GOV | 1 | Mar 20, 2018 | clinicaltrials |
| NCT03415815 | An Observational Study to Evaluate Lymph Metastases and Prognoses of the Patients With Esophageal Cancer | unknown | — | 3,673 | Henan Cancer HospitalOTHER_GOV | 1 | Jan 30, 2018 | clinicaltrials |
| NCT03286920 | Effect of Postoperative Family Nutrition Mode on Weight/BMI of Patients With Esophageal Cancer | unknown | — | 600 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jan 23, 2018 | clinicaltrials |
| NCT03366883 | Paclitaxel, Cisplatin,5-FU vs. Radiotherapy Plus Paclitaxel, Cisplatin as Preoperative Therapy for Locally Advanced ESC | unknown | Phase 3 | 420 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jan 9, 2018 | clinicaltrials |
| NCT03126708 | Cetuximab in Combination With Paclitaxel Plus Cisplatin Versus Paclitaxel Plus Cisplatin Alone for the First-line Treatment of Metastatic Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 150 | Peking UniversityOTHER | 1 | Jan 4, 2018 | clinicaltrials |
| NCT02545751 | SBRT Combined With Thymalfasin for Metastatic Esophageal Cancer | unknown | Phase 2 | 29 | Hangzhou Cancer HospitalOTHER | 1 | Nov 28, 2017 | clinicaltrials |
| NCT03273647 | Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma With Positive Circumstantial Resection Margin | unknown | Phase 3 | 60 | Fudan UniversityOTHER | 0 | Oct 19, 2017 | clinicaltrials |
| NCT02653521 | The Clinical Physics Research of Image Guided Adaptive Radiation Therapy for Esophagus Cancer | unknown | N/A | 80 | Sun Yat-sen UniversityOTHER | 1 | Oct 11, 2017 | clinicaltrials |
| NCT02850172 | Effects of a "Walk, Eat, & Breathe" Nursing Intervention For Patients With Esophageal Cancer | unknown | N/A | 144 | National Taiwan University HospitalOTHER | 1 | Sep 26, 2017 | clinicaltrials |
| NCT02384811 | Phase II Study of Extensive Clinical Target Volumes in Postoperative Radiotherapy for Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 70 | Fudan UniversityOTHER | 1 | Sep 7, 2017 | clinicaltrials |
| NCT03273686 | Efficacy of Nasogastric Tube Application in Postoperative Care of Esophagectomy | unknown | Phase 3 | 100 | Fudan UniversityOTHER | 0 | Sep 6, 2017 | clinicaltrials |
| NCT00987857 | Endoscopy Every 2 Years or Only as Needed in Monitoring Patients With Barrett Esophagus | unknown | N/A | 3,400 | Gloucestershire Hospitals NHS Foundation TrustOTHER | 1 | Aug 22, 2017 | clinicaltrials |
| NCT03224221 | Apatinib Combined With Chemotherapy for Esophageal Squamous Cell Cancer After the Failure of Standard Treatment | unknown | Phase 2 | 189 | The First Affiliated Hospital of Anhui Medical UniversityOTHER | 1 | Jul 21, 2017 | clinicaltrials |
| NCT02959385 | A Phase II Trial to Compare Efficacy and Safety of CRT VS Neo-CRT in Patients Who Achieved CCR for Esophageal Cancer | unknown | Phase 2 | 40 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Jul 18, 2017 | clinicaltrials |
| NCT03216135 | Microbiome Involvement With Barrett's Esophagus and Progression to Esophageal Adenocarcinoma | unknown | — | 50 | Ochsner Health SystemOTHER | 1 | Jul 13, 2017 | clinicaltrials |
| NCT02913066 | S-1 IMRT Versus S-1 and Cisplatin Concurrent IMRT in Inoperable Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 88 | Mianyang Central HospitalOTHER | 1 | Jun 16, 2017 | clinicaltrials |
| NCT03176680 | The Effects on Major Organ Complications on Esophagectomy of New Anesthetic ERAS Strategy: a Prospective Investigation(ERAS) | unknown | N/A | 120 | National Taiwan University HospitalOTHER | 1 | Jun 5, 2017 | clinicaltrials |
| NCT02547610 | MR/PET in the Evaluation of Patients With Esophageal Cancer | unknown | — | 80 | National Taiwan University HospitalOTHER | 1 | May 16, 2017 | clinicaltrials |
| NCT00816634 | Efficacy Comparison Study of Combination Regimens to Treat Advanced Esophageal Squamous Cell Carcinoma(XP versus XT) | unknown | Phase 2 | 94 | Samsung Medical CenterOTHER | 1 | May 1, 2017 | clinicaltrials |
| NCT01216527 | Phase III Study of Neo-adjuvant Chemoradiotherapy Followed by Surgery for Squamous Cell Esophageal Cancer | unknown | Phase 3 | 430 | Sun Yat-sen UniversityOTHER | 1 | Feb 27, 2017 | clinicaltrials |
| NCT01438385 | Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders | unknown | — | 12,000 | Weill Medical College of Cornell UniversityOTHER | 1 | Feb 20, 2017 | clinicaltrials |
| NCT02762474 | Trial of Concurrent Chemoradiotherapy for Locally Advanced Esophageal Cancer | unknown | Phase 1 / Phase 2 | 30 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Feb 7, 2017 | clinicaltrials |
| NCT01555801 | Endoscopic Ultrasound Plus Submucosal Injection for Early Esophageal Cancer | unknown | N/A | 80 | Sun Yat-sen UniversityOTHER | 1 | Jan 25, 2017 | clinicaltrials |
| NCT03029793 | Biomarkers and Functional Imaging in Predicting Response of Esophageal Cancer | unknown | — | 200 | Air Force Military Medical University, ChinaOTHER | 1 | Jan 24, 2017 | clinicaltrials |
| NCT03013712 | A Clinical Research of CAR T Cells Targeting EpCAM Positive Cancer(CARTEPC) | unknown | Phase 1 / Phase 2 | 60 | First Affiliated Hospital of Chengdu Medical CollegeOTHER | 1 | Jan 6, 2017 | clinicaltrials |
| NCT01927328 | Iron Replacement in Oesophagogastric Neoplasia(IRON) | unknown | Phase 4 | 40 | Nottingham University Hospitals NHS TrustOTHER | 1 | Oct 28, 2016 | clinicaltrials |
| NCT02938195 | Phase II Study of Neo-adjuvant Chemoradiotherapy for Squamous Cell Esophageal Cancer | unknown | Phase 2 | 50 | Shanghai Chest HospitalOTHER | 1 | Oct 19, 2016 | clinicaltrials |
| NCT02544737 | Apatinib for Metastatic Esophageal Cancer. | unknown | Phase 2 | 29 | Hangzhou Cancer HospitalOTHER | 1 | Aug 26, 2016 | clinicaltrials |
Data updated 23 days agoSource updated Apr 10, 2019source: clinicaltrials