Clinical trial · Interventional
HOPE - A Study to Evaluate the Effect of a Prehabilitation Program on GI Cancer Patients Planning to Undergo Surgery
H.O.P.E. Healing Optimization Through Preoperative Engagement: A Prospective Single Cohort Study to Evaluate the Effect of a Prehabilitation Program on Preoperative Outcomes in Upper GI Surgical Oncology Patients
NCT03642093CI-TRIAL-00034804HOPEunknownPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
A one-group prospective cohort study design with measures collected pre- and post-intervention. The primary goal of this study is to evaluate the effect of a multimodal prehabilitation preoperative program on changes in frailty in upper gastrointestinal surgical oncology patients.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Nutritional Intervention | Combination Product | — | UNRESOLVED |
| Physical Activity Intervention | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Frail
- description
- Subjects assessed and determined to be Frail and meet trial eligibility criteria will be enrolled on Frail Arm and begin a 4 Week program consisting of Nutritional Interventions and Physical Activity Interventions
- interventionNames
- Combination Product: Nutritional Intervention
- Behavioral: Physical Activity Intervention
- type
- ACTIVE_COMPARATOR
- label
- Not Frail
- description
- Subjects assessed and determined to be Not Frail and meet trial eligibility criteria will be enrolled on Not Frail Arm and begin a 4 Week program consisting of Nutritional Interventions and Physical Activity Interventions
- interventionNames
- Combination Product: Nutritional Intervention
- Behavioral: Physical Activity Intervention
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 25 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * All patients must be patients of Ochsner being seen at the Ochsner Medical Center (OMC). * All patients must be 25 to 80 years of age. * All patients must have a diagnosis of cancer. * \> 10 pound unintentional weight loss within 1 year * Ability to perform grip strength test and Timed Up and Go (TUG) test * Willingness to participate in the study, document compliance, and attend clinical appointments * All patients must be undergoing one of the following major elective surgical oncologic resections with curative intent: * Pancreaticoduodenectomy for pancreatic cancer * Distal pancreatectomy / splenectomy for pancreatic cancer * Esophageal robotic assisted laparoscopic thoracoscopic esophagectomy for esophageal cancer * Laparoscopic or open, partial or total gastrectomy for gastric cancer Exclusion Criteria: * All patients not undergoing oncologic or major resections. * All patients unwilling or unable to answer questionnaires or accept help to answer electronic or paper questionnaires. * All patients that are unable to participate in an activity program. * All patients unable to wear an electronic activity monitoring device. * All patients not wanting to follow a specific nutritional and breathing intervention. * All patients that are not able or wishing to consent.
References
Publications (0)
Data not yet available
No reference posted for this study.