Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
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Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00215644 | Matuzumab Treatment With Epirubicin, Cisplatin and Capecitabine (ECX) in Esophago-Gastric Cancer(MATRIX EG) | completed | Phase 2 | 72 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 4 | Nov 2, 2018 | clinicaltrials |
| NCT00137813 | Avastin and Taxotere for Esophagogastric Cancer | completed | Phase 2 | 42 | Dana-Farber Cancer InstituteOTHER | 1 | Nov 1, 2018 | clinicaltrials |
| NCT03223662 | Metabolomic and BH3 Profiling of Esophageal Cancers: Identification of Novel Assessment Methods of Treatment Response for Precision Therapy | terminated | Phase 2 | 2 | National Cancer Institute (NCI)NIH | 1 | Oct 30, 2018 | clinicaltrials |
| NCT02239328 | A Study of Patient-reported Outcomes in Patients With Lung or Esophageal Cancer | completed | — | 182 | University of VirginiaOTHER | 1 | Oct 26, 2018 | clinicaltrials |
| NCT00531180 | 4-Dimensional CT Derived Ventilation Versus SPECT Aerosol Ventilation in Patients With Thoracic Malignancies | completed | Phase 2 | 31 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 25, 2018 | clinicaltrials |
| NCT03712774 | Prospective Observational Trial to Evaluate Quality of Life After Neoadjuvant or Definitive Chemoradiation in Patients With Esophageal Cancer(ESOCARE) | recruiting | — | 60 | Ludwig-Maximilians - University of MunichOTHER | 1 | Oct 19, 2018 | clinicaltrials |
| NCT01591135 | A Phase III Study of Comparing Paclitaxel Plus 5-Fluorouracil Versus Cisplatin Plus 5-Fluorouracil in Chemoradiotherapy for Locally Advanced Esophageal Carcinoma | completed | Phase 3 | 436 | Fudan UniversityOTHER | 1 | Oct 18, 2018 | clinicaltrials |
| NCT02234180 | Regorafenib in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction Who Have Completed Chemoradiation Therapy and Surgery | terminated | Phase 2 | 3 | Academic and Community Cancer Research UnitedOTHER | 1 | Oct 17, 2018 | clinicaltrials |
| NCT03274349 | Whole Body Electromyostimulation and Nutritional Therapy for Patients With Esophageal and Bronchial Carcinoma | unknown | N/A | 150 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Oct 16, 2018 | clinicaltrials |
| NCT03706326 | CAR T and PD-1 Knockout Engineered T Cells for Esophageal Cancer | unknown | Phase 1 / Phase 2 | 20 | The First Affiliated Hospital of Guangdong Pharmaceutical UniversityOTHER | 1 | Oct 16, 2018 | clinicaltrials |
| NCT03708042 | A Study to Compare Efficacy and Safety of DRT VS CRT Plus Surgery in Patients Who Achieved CCR for Esophageal Cancer | unknown | Phase 3 | 220 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Oct 16, 2018 | clinicaltrials |
| NCT00735826 | A Clinical Trial to Validate Molecular Targets of Vorinostat in Patients With Aerodigestive Tract Cancer | completed | N/A | 10 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Oct 12, 2018 | clinicaltrials |
| NCT03220009 | Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma | withdrawn | Phase 2 | 0 | National Cancer Institute (NCI)NIH | 1 | Oct 3, 2018 | clinicaltrials |
| NCT00096031 | S0415 Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer | completed | Phase 2 | 63 | SWOG Cancer Research NetworkNETWORK | 1 | Sep 26, 2018 | clinicaltrials |
| NCT03213054 | A Study of OBP-301 With Radiation Therapy in Patients With Esophageal Cancer | unknown | Phase 1 | 12 | Oncolys BioPharma IncINDUSTRY | 1 | Sep 26, 2018 | clinicaltrials |
| NCT01471249 | Quality of Life and Dysphagia Following Palliative Stenting in Esophageal Cancer | terminated | — | 13 | Centre hospitalier de l'Université de Montréal (CHUM)OTHER | 1 | Sep 17, 2018 | clinicaltrials |
| NCT03668418 | Xenotransplantation of Primary Cancer Samples in Zebrafish Embryos(xenoZ) | unknown | — | 120 | University of PisaOTHER | 1 | Sep 12, 2018 | clinicaltrials |
| NCT03642093 | HOPE - A Study to Evaluate the Effect of a Prehabilitation Program on GI Cancer Patients Planning to Undergo Surgery(HOPE) | unknown | Phase 4 | 60 | Siobhan TrotterOTHER | 1 | Sep 11, 2018 | clinicaltrials |
| NCT02358863 | Molecularly Tailored Therapy for Patients With Metastatic Cancer of the Esophagus and Stomach(mEGA) | terminated | N/A | 13 | Georgetown UniversityOTHER | 1 | Sep 6, 2018 | clinicaltrials |
| NCT03397745 | Bispectral Index Throughout Esophageal Cancer Operation | completed | N/A | 44 | Samsung Medical CenterOTHER | 1 | Sep 4, 2018 | clinicaltrials |
| NCT03649945 | Endostatin Combined With Chemotherapy for Adjuvant Treatment of Esophageal Cancer | unknown | Phase 2 | 186 | First Affiliated Hospital of Guangxi Medical UniversityOTHER | 0 | Aug 28, 2018 | clinicaltrials |
| NCT00607594 | Saracatinib in Treating Patients With Locally Advanced or Metastatic Stomach or Gastroesophageal Junction Cancer | completed | Phase 2 | 21 | National Cancer Institute (NCI)NIH | 2 | Aug 23, 2018 | clinicaltrials |
| NCT01608464 | Pre-op Chemo-RT w/CDDP/5FU vs Chemo w/ Docetaxel/Irinotecan in PET Non Responder Resectable Esophagus Cancer | terminated | Phase 2 | 170 | King Faisal Specialist Hospital & Research CenterOTHER | 1 | Aug 10, 2018 | clinicaltrials |
| NCT00891878 | Capecitabine With or Without Sunitinib Malate as First-Line Therapy in Treating Patients With Metastatic Cancer of the Esophagus or Gastroesophageal Junction | completed | Phase 2 | 12 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jul 24, 2018 | clinicaltrials |
| NCT00711412 | Capecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients With Esophageal or Gastroesophageal Junction Cancer | completed | Phase 2 | 44 | Northwestern UniversityOTHER | 1 | Jul 18, 2018 | clinicaltrials |
| NCT03585673 | Docetaxel-polymeric Micelles(PM) and Oxaliplatin for Esophageal Carcinoma(DOSE) | unknown | Phase 2 | 38 | Sung Yong OhOTHER | 1 | Jul 17, 2018 | clinicaltrials |
| NCT01051479 | A Pilot C11-Choline PET-CT Imaging Study in Patients With Locally Advanced Esophageal Cancer | completed | Phase 1 | 22 | Wake Forest University Health SciencesOTHER | 1 | Jul 2, 2018 | clinicaltrials |
| NCT01561014 | Oxaliplatin, Fluorouracil, Erlotinib Hydrochloride, and Radiation Therapy Before Surgery and Erlotinib Hydrochloride After Surgery in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction | completed | Phase 1 | 9 | Wake Forest University Health SciencesOTHER | 1 | Jul 2, 2018 | clinicaltrials |
| NCT02611245 | NIR Fluorescence Imaging Technique in Thoracic Surgery With ICG | completed | Phase 1 | 36 | Chinese Academy of SciencesOTHER_GOV | 1 | Jun 8, 2018 | clinicaltrials |
| NCT00790569 | Varenicline or Nicotine Patch and Nicotine Gum in Helping Smokers in a Methadone Treatment Program Stop Smoking | completed | N/A | 315 | Butler HospitalOTHER | 1 | Jun 6, 2018 | clinicaltrials |
| NCT01746043 | A Phase II Study of Minocycline and Armodafinil for Reducing the Symptom Burden Produced by Chemoradiation Treatment for Esophageal Cancer | completed | Phase 2 | 22 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 6, 2018 | clinicaltrials |
| NCT01738633 | Quality of Life After Esophagectomy for Cancer - Step 2 | terminated | N/A | 80 | University of PadovaOTHER | 1 | May 23, 2018 | clinicaltrials |
| NCT03428074 | A Observational Study to Compare Effectiveness and Safety of the Surgeries in Patients With Esophageal Cancer | completed | — | 1,862 | Chinese PLA General HospitalOTHER | 1 | May 21, 2018 | clinicaltrials |
| NCT00316862 | Cisplatin, Irinotecan, and Radiation Therapy in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer That Can Be Removed By Surgery | completed | Phase 2 | 82 | Alliance for Clinical Trials in OncologyOTHER | 1 | May 8, 2018 | clinicaltrials |
| NCT01807390 | Perspectives of Receiving Open Versus Minimally Invasive Surgery(PROMIS) | unknown | — | 200 | Ottawa Hospital Research InstituteOTHER | 1 | Apr 17, 2018 | clinicaltrials |
| NCT02435602 | The Role of Chromoendoscopy in the Early Detection of Esophageal Cancer in Patients With Prior Head and Neck Cancers | completed | N/A | 294 | Maria Sklodowska-Curie National Research Institute of OncologyOTHER | 1 | Apr 13, 2018 | clinicaltrials |
| NCT03492827 | Evaluation of the Preventive Effect of Chlorhexidine Acetate Gargle for Upper Gastrointestinal Tract Infection After ESD | unknown | N/A | 306 | Peking University Third HospitalOTHER | 1 | Apr 10, 2018 | clinicaltrials |
| NCT02638909 | Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal Malignancies | terminated | Phase 2 | 4 | Criterium, Inc.INDUSTRY | 1 | Apr 2, 2018 | clinicaltrials |
| NCT00938470 | Docetaxel, Oxaliplatin, Capecitabine, Fluorouracil, and Radiation Therapy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction | completed | Phase 2 | 73 | Alliance for Clinical Trials in OncologyOTHER | 1 | Mar 29, 2018 | clinicaltrials |
| NCT01666158 | Prehabilitation for Esophageal Resection Surgery | completed | N/A | 68 | Franco CarliOTHER | 1 | Mar 21, 2018 | clinicaltrials |
| NCT02924909 | Phase II Trial of Neoadjuvant Treatment and Minimal Invasive Surgery for Esophageal and GEJ Cancer(QUIMERA) | unknown | Phase 2 | 50 | Instituto Nacional de Cancer, BrazilOTHER_GOV | 1 | Mar 20, 2018 | clinicaltrials |
| NCT03462524 | Neoadjuvant Therapy for Esophageal Cancer and Cardiopulmonary Physiology | completed | — | 384 | St. James's Hospital, IrelandOTHER | 1 | Mar 12, 2018 | clinicaltrials |
| NCT00827671 | Study of Combination of Cetuximab and Radiotherapy Added to the Standard Treatment for Oesophageal Adenocarcinoma(TRACC) | terminated | Phase 2 | 12 | P.O. WitteveenOTHER | 1 | Mar 9, 2018 | clinicaltrials |
| NCT01627379 | Cisplatin and 5-FU +/- Panitumumab for Patients With Nonresectable,Advanced or Metastatic Esophageal Squamous Cell Cancer(POWER) | terminated | Phase 3 | 300 | AIO-Studien-gGmbHOTHER | 1 | Mar 2, 2018 | clinicaltrials |
| NCT03384511 | The Use of 18F-ALF-NOTA-PRGD2 PET/CT Scan to Predict the Efficacy and Adverse Events of Apatinib in Malignancies. | completed | Phase 4 | 38 | Shandong Cancer Hospital and InstituteOTHER | 1 | Feb 20, 2018 | clinicaltrials |
| NCT02392377 | Molecular Phenotyping in Predicting Response in Patients With Stage IB-III Esophageal Cancer Receiving Combination Chemotherapy | terminated | Phase 2 | 1 | Case Comprehensive Cancer CenterOTHER | 1 | Feb 13, 2018 | clinicaltrials |
| NCT03410758 | Predictive Factors of Survival With and Without Repetition With 5 and 10 Years Curative Post-oesophagectomy for Cancer of the Oesophagus(RESARPO) | completed | — | 245 | University Hospital, BrestOTHER | 1 | Feb 7, 2018 | clinicaltrials |
| NCT01612546 | Pilot Trial of CRLX101 in Treatment of Patients With Advanced or Metastatic Stomach, Gastroesophageal, or Esophageal Cancer That Cannot be Removed by Surgery | completed | Phase 2 | 10 | City of Hope Medical CenterOTHER | 1 | Feb 1, 2018 | clinicaltrials |
| NCT03415815 | An Observational Study to Evaluate Lymph Metastases and Prognoses of the Patients With Esophageal Cancer | unknown | — | 3,673 | Henan Cancer HospitalOTHER_GOV | 1 | Jan 30, 2018 | clinicaltrials |
| NCT00256269 | Oxaliplatin and Irinotecan in Recurrent or Metastatic Esophageal and Gastroesophageal (GE) Junction Carcinoma | terminated | Phase 2 | 4 | University of California, IrvineOTHER | 1 | Jan 26, 2018 | clinicaltrials |
Data updated 23 days agoSource updated Nov 2, 2018source: clinicaltrials