Clinical trial · Observational
A Observational Study to Compare Effectiveness and Safety of the Surgeries in Patients With Esophageal Cancer
A Multi-centre Real-world Non-interventional Observational Study to Compare Effectiveness and Safety of the Minimally Invasive Surgeries of Ivor-Lewis and Mckeown in Chinese Patients With IA-IIIB Esophageal Cancer
NCT03428074CI-TRIAL-00033016completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study was designed to compare effectiveness and safety of the surgeries of Ivor-Lewis and Mckeown in patients with esophageal cancer
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Surgeries | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Patients with the surgery of Ivor-Lewis
- description
- Pathologically diagnosed IA-IIIB patients with esophageal cancer who received minimally invasive surgery of Ivor-Lewis
- interventionNames
- Procedure: Surgeries
- label
- Patients with the surgery of Mckeown
- description
- Pathologically diagnosed IA-IIIB patients with esophageal cancer who received minimally invasive surgery of Mckeown
- interventionNames
- Procedure: Surgeries
Primary outcomes (1)
- measure
- Overall survivals in patients with esophageal cancer who received surgeries
- timeFrame
- 2010 - 2017
- description
- Overall survivals in patients with esophageal cancer who received surgeries categorised by tumor biological characteristics
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Pathologically diagnosed middle and lower thoracic IA-IIIB esophageal cancer after surgeries; * Patients who received minimally invasive radical dissections of Ivor-Lewis and Mckeown; * Patients who received tubular gastroesophageal reconstruction; Exclusion Criteria: * Patients complicated with arrhythmia, or serious disfunctions of heart, lung, liver, and kidney before surgeries; * Patients with second primary tumors; * Patients who received abdominal or thoracic surgeries; * Patients who received gastrostomy or nesteostomy before surgeries; * Patients with suspected cervical lymph metastases (in the subgroup of the patients who received the surgery of Mckeown)
References
Publications (1)
- DERIVEDZhang T, Hou X, Li Y, Fu X, Liu L, Xu L, Liu Y. Effectiveness and safety of minimally invasive Ivor Lewis and McKeown oesophagectomy in Chinese patients with stage IA-IIIB oesophageal squamous cell cancer: a multicentre, non-interventional and observational study. Interact Cardiovasc Thorac Surg. 2020 Jun 1;30(6):812-819. doi: 10.1093/icvts/ivaa038. PMID 32285107