Clinical trial · Observational
Prospective Observational Trial to Evaluate Quality of Life After Neoadjuvant or Definitive Chemoradiation in Patients With Esophageal Cancer
NCT03712774CI-TRIAL-00035385ESOCARErecruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Prospective observational study to evaluate the Quality of life based on standardized EORTC questionaires as well as toxicities, functional and oncological outcomes in patients treated with neoadjuvant or definitive chemoradiation for esophageal Cancer.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chemoradiation | — | UNRESOLVED | — |
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
| Quality of Life | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EORTC OG-25 | Other | — | UNRESOLVED |
| EORTC QLQ C30 | Other | — | UNRESOLVED |
| EORTC QLQ OES-18 | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- neoadjuvant chemoradiation
- description
- Patient with esophageal Cancer treated by neoadjuvant chemoradiation followed by surgery will be longitudinally evaluated by questionaires EORTC QLQ C30, EORTC QLQ OES-18 and EORTC OG-25
- interventionNames
- Other: EORTC QLQ C30
- Other: EORTC QLQ OES-18
- Other: EORTC OG-25
- label
- definitive chemoradiation
- description
- Patient with esophageal Cancer treated by definitive chemoradiation will be longitudinally evaluated by questionaires EORTC QLQ C30, EORTC QLQ OES-18 and EORTC OG-25
- interventionNames
- Other: EORTC QLQ C30
- Other: EORTC QLQ OES-18
- Other: EORTC OG-25
Primary outcomes (1)
- measure
- Quality of life
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * histologically proven esophageal Cancer (SCC or adenocarcinoma) without distant metastases (except supraclavicular nodes) * indication for neoadjuvant or definitive chemoradiation using either cisplatin/5-FU or carboplatin/paclitaxel with curative intent * age \>= 18 years * written informed consent * ability to answer the standardized questionaires according to the treating physician Exclusion Criteria: * age \< 18 years * Treatment with palliative intent * distant metastases (except supraclavicular nodes) * second malignancy * Prior systemic treatment for esophageal Cancer * Treatment in an interventional study
References
Publications (0)
Data not yet available
No reference posted for this study.