Cancer
Malignant Esophageal Neoplasm
CI-CAN-00001127Explore in graph →
Top-level518 active trials6 approved drugs12 evidence items
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Cancer
CI-CAN-00001127Explore in graph →
Clinical trials
1,926 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (169)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03482791 | Proton Beam Therapy in the Treatment of Esophageal Cancer | active not recruiting | N/A | 22 | Washington University School of MedicineOTHER | 1 | Apr 2, 2026 | clinicaltrials |
| NCT05145647 | To Observe the Benefit of Adding Brachytherapy After CCRT on Resectable Esophageal Cancer Patients Without Surgery | active not recruiting | N/A | 18 | Chang Gung Memorial HospitalOTHER | 1 | Mar 27, 2026 | clinicaltrials |
| NCT06792786 | A Multicenter Prospective Study Evaluating Concurrent Chemoradiotherapy Following Induction Immunochemotherapy for Esophageal Cancer Based on Dynamic ctDNA Monitoring | recruiting | N/A | 30 | The Central Hospital of Lishui CityOTHER | 1 | Mar 23, 2026 | clinicaltrials |
| NCT07175155 | Combination of COMBO Endoscopy Oropharyngeal Airway and HFNC Oxygenation in Sedated Gastrointestinal Endoscopy for Morbidly Obese Patients | recruiting | N/A | 410 | Zhejiang UniversityOTHER | 1 | Mar 11, 2026 | clinicaltrials |
| NCT06523374 | A Study of Barrett's Esophagus Patients to Investigate Quality of Life and Fear of Cancer, and Optimize a Risk Model Based on Biomarkers and New Technologies to Better Predict the Development of Cancer(Endeavor-1) | recruiting | N/A | 50 | University Hospital, AntwerpOTHER | 6 | Feb 24, 2026 | clinicaltrials |
| NCT04258813 | Onco-primary Care Networking to Support TEAM-based Care(ONE TEAM) | active not recruiting | N/A | 313 | Duke UniversityOTHER | 1 | Feb 20, 2026 | clinicaltrials |
| NCT03896399 | Laparoscopic Ischemic Conditioning Prior to Esophagectomy(ISCON) | completed | N/A | 22 | UMC UtrechtOTHER | 2 | Feb 19, 2026 | clinicaltrials |
| NCT06346080 | Molecular Analysis for Gastro-Esophageal Cancer: Multicenter Discrete Choice Experiment(MAGECmultiDiCE) | recruiting | N/A | 2,200 | KU LeuvenOTHER | 1 | Feb 18, 2026 | clinicaltrials |
| NCT07416825 | Inter-Observer Delineation Differences in Esophageal Cancer GTV on MR, CT, and PET/CT Protokol šečerov Ermenc 28dec19 | completed | N/A | 23 | Institute of Oncology LjubljanaOTHER | 1 | Feb 18, 2026 | clinicaltrials |
| NCT06346054 | Molecular Assessment for Gastro-Esophageal Cancer(MAGEC) | recruiting | N/A | 1,000 | KU LeuvenOTHER | 1 | Feb 17, 2026 | clinicaltrials |
| NCT06027515 | Esophageal Cancer Multimodal Prehabilitation Study | completed | N/A | 15 | Massachusetts General HospitalOTHER | 1 | Feb 12, 2026 | clinicaltrials |
| NCT00628368 | Biological Factors in Predicting Response to Treatment in Patients With Esophageal Cancer or Rectal Cancer | completed | N/A | 160 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT05775939 | PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients With Lung or Esophageal Cancer, EUCLID Trial | recruiting | N/A | 20 | Thomas Jefferson UniversityOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT04217239 | A Comparison Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy | completed | N/A | 272 | The Second Hospital of Shandong UniversityOTHER | 1 | Feb 5, 2026 | clinicaltrials |
| NCT03961945 | Minimally Invasive Molecular Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Adenocarcinoma | recruiting | N/A | 1,550 | Mayo ClinicOTHER | 1 | Jan 26, 2026 | clinicaltrials |
| NCT07363629 | Impact of Preserving Versus Ligating the Right Gastric Artery on Anastomotic Outcomes After McKeown Esophagectomy: A Randomized Controlled Trial | completed | N/A | 120 | The First Hospital of Hebei Medical UniversityOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT06430346 | Exercise Prehabilitation for Locoregional Esophageal Cancer | recruiting | N/A | 20 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT07155330 | High-flow Nasal Cannula Oxygenation in Sedated Endoscopy for High-risk Obstructive Sleep Apnea Patients | completed | N/A | 80 | Zhejiang UniversityOTHER | 1 | Nov 25, 2025 | clinicaltrials |
| NCT07236320 | Neoadjuvant Immunochemotherapy vs Chemoradiotherapy in ESCC | completed | N/A | 200 | Yongtao HanOTHER | 1 | Nov 19, 2025 | clinicaltrials |
| NCT06129487 | Evaluations of Alcohol Warning Labels | completed | N/A | 1,053 | University of ConnecticutOTHER | 1 | Nov 14, 2025 | clinicaltrials |
| NCT03819088 | Effects on Quality of Life With Zinc Supplementation in Patients With Gastrointestinal Cancer | completed | N/A | 17 | Emory UniversityOTHER | 1 | Oct 9, 2025 | clinicaltrials |
| NCT04526886 | Clinical Trial of a Novel Dose Adjustment Algorithm for Preventing Cytopenia-Related Delays During FOLFOX Chemotherapy | completed | N/A | 52 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Oct 6, 2025 | clinicaltrials |
| NCT05051475 | Endoscopic Radiofrequency Ablation Versus Hybrid Argon Plasma Coagulation in the Treatment of Barrett's Esophagus(RATE) | completed | N/A | 62 | Centre of Postgraduate Medical EducationOTHER | 1 | Oct 3, 2025 | clinicaltrials |
| NCT07104838 | Non-intubated Versus Intubated Anesthesia in Thoracoscopic Esophagectomy for Esophageal Cancer | not yet recruiting | N/A | 500 | The First Affiliated Hospital of Guangzhou Medical UniversityOTHER | 0 | Sep 25, 2025 | clinicaltrials |
| NCT07180134 | Health Informatics and Resistance Exercise for Symptom Management and Quality of Life in Post-Esophagectomy Patients | not yet recruiting | N/A | 90 | Chang Gung Memorial HospitalOTHER | 0 | Sep 18, 2025 | clinicaltrials |
| NCT04938973 | NIF-Guided RAMIE Using ICG Versus OTE Feasibility RCT(RAMIE vs OTE) | terminated | N/A | 24 | St. Joseph's Healthcare HamiltonOTHER | 1 | Sep 17, 2025 | clinicaltrials |
| NCT06796764 | COMBO Endoscopy Oropharyngeal Airway Reduces Hypoxia During Sedated Gastrointestinal Endoscopy in Obese Patients: A Multicenter, Randomized, Controlled Clinical Trial | recruiting | N/A | 580 | Zhejiang UniversityOTHER | 1 | Sep 10, 2025 | clinicaltrials |
| NCT02415101 | Timing of Resective Surgery After Neoadjuvant Chemoradiotherapy in Esophageal Cancer(NeoResII) | completed | N/A | 202 | Karolinska University HospitalOTHER | 1 | Sep 3, 2025 | clinicaltrials |
| NCT06420908 | Adebrelimab Combined With Chemoradiotherapy for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma (ESCC) | withdrawn | N/A | 0 | Hebei Medical University Fourth HospitalOTHER | 0 | Aug 26, 2025 | clinicaltrials |
| NCT06275165 | The Effects of Acupressure on Improving Postoperative Gastrointestinal Symptom Distress in Esophageal Cancer Patients | completed | N/A | 48 | CHEN, CHIA-CHENOTHER | 1 | Aug 7, 2025 | clinicaltrials |
| NCT02534233 | Evaluation of Effect of CryoBalloon Focal Ablation System on Human Esophageal Epithelium(ColdPlay2) | completed | N/A | 58 | Johns Hopkins UniversityOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT03161535 | Effectiveness of a Rehabilitation Program in Improving Quality of Life in Patients With Esophageal Cancer | active not recruiting | N/A | 85 | Taipei Veterans General Hospital, TaiwanOTHER_GOV | 1 | Jul 28, 2025 | clinicaltrials |
| NCT07067359 | The Intensive Nutritional Support in Esophageal Cancer Undergoing Neoadjuvant Therapy(INSECNT) | not yet recruiting | N/A | 200 | Sichuan UniversityOTHER | 0 | Jul 16, 2025 | clinicaltrials |
| NCT07067450 | Adjuvant Immunotherapy for Esophageal Squamous Cell Carcinoma | not yet recruiting | N/A | 98 | Sichuan UniversityOTHER | 0 | Jul 16, 2025 | clinicaltrials |
| NCT06030180 | CLUE: CLinical Utility Study of EsoGuard(PR-0410) | completed | N/A | 566 | Lucid Diagnostics, Inc.INDUSTRY | 1 | Jun 27, 2025 | clinicaltrials |
| NCT06081647 | The Efficacy and Safety of the COMBO Endoscopy Oropharyngeal Airway in Gastrointestinal Endoscopy Procedure | recruiting | N/A | 1,200 | RenJi HospitalOTHER | 1 | Jun 25, 2025 | clinicaltrials |
| NCT07024849 | Developing an Ecological and Tailored Nutritional Intervention to Improve Quality of Life in Esophageal Cancer Survivors | recruiting | N/A | 30 | Samsung Medical CenterOTHER | 1 | Jun 17, 2025 | clinicaltrials |
| NCT07004634 | Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE) | recruiting | N/A | 75 | Ruijin HospitalOTHER | 1 | Jun 10, 2025 | clinicaltrials |
| NCT05405530 | Nasal Mask Kit in Gastrointestinal Endoscopy(NASO) | completed | N/A | 1,204 | RenJi HospitalOTHER | 1 | Jun 5, 2025 | clinicaltrials |
| NCT06997302 | A Study on the Impact of Intelligent Nutrition Management on Clinical Outcomes in Chemotherapy Patients With Gastrointestinal Malignancies | active not recruiting | N/A | 150 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | May 30, 2025 | clinicaltrials |
| NCT06986291 | Radiation-induced Toxicity of the Heart(CorTox) | not yet recruiting | N/A | 325 | Technische Universität DresdenOTHER | 1 | May 29, 2025 | clinicaltrials |
| NCT06876454 | Optimal Nutritional Palliation of Obstructed GEJ Cancer | not yet recruiting | N/A | 33 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sOTHER | 1 | May 25, 2025 | clinicaltrials |
| NCT06990178 | Adaptive Neoadjuvant Therapy for Esophageal Cancer | enrolling by invitation | N/A | 43 | Cancer Hospital Chinese Academy of Medical Science, Shenzhen CenterOTHER | 1 | May 25, 2025 | clinicaltrials |
| NCT06979986 | SLND Versus Non-Dissection Following ESD for T1a Stage Esophageal Squamous Cell Carcinoma | not yet recruiting | N/A | 102 | Fujian Cancer HospitalOTHER_GOV | 0 | May 20, 2025 | clinicaltrials |
| NCT06668454 | Chemoimmunotherapy Followed by Surgery for Oligometastatic Esophagogastric Cancer: (TORO Protocol)(TORO) | recruiting | N/A | 72 | University Health Network, TorontoOTHER | 1 | May 16, 2025 | clinicaltrials |
| NCT04734821 | Fluorescence Image Guided Foregut Surgery(FOREGUT) | recruiting | N/A | 60 | IHU StrasbourgOTHER | 1 | May 1, 2025 | clinicaltrials |
| NCT02311712 | Non-endoscopic EC Screening Program in Northern Iran(NESP) | suspended | N/A | 12,000 | Tehran University of Medical SciencesOTHER | 0 | Apr 16, 2025 | clinicaltrials |
| NCT06926374 | Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery | recruiting | N/A | 90 | Chinese University of Hong KongOTHER | 1 | Apr 16, 2025 | clinicaltrials |
| NCT05706025 | Study to Evaluate EnteroTracker® as a Sampling Method to Screen for Barrett's Esophagus/Esophageal Cancer | enrolling by invitation | N/A | 60 | University of Colorado, DenverOTHER | 1 | Apr 6, 2025 | clinicaltrials |
| NCT03429816 | OPPOSITE: Outcome Prediction of Systemic Treatment in Esophagogastric Carcinoma(OPPOSITE) | completed | N/A | 120 | University Hospital HeidelbergOTHER | 1 | Mar 27, 2025 | clinicaltrials |
Data updated 22 days agoSource updated Apr 2, 2026source: clinicaltrials