Clinical trial · Interventional
Esophageal Cancer Multimodal Prehabilitation Study
A Multimodal Prehabilitation Feasibility Study for Older Adult Patients at High Risk for Poor Postoperative Outcomes Prior to Esophageal Cancer Surgery
NCT06027515CI-TRIAL-00103179completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this research study is to investigate the feasibility of implementing a prehabilitation program that aims to improve a patient's physical, nutritional, and sleep health before surgery in an older, at-risk group with esophageal cancer.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
| Esophageal Neoplasms | Esophageal Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Prehabilitation Program | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Prehabilitation Program
- description
- 30 participants will be enrolled and will complete study procedures as follows: * Enrollment at least 4 weeks prior to esophageal cancer surgery. * In-person clinic visit with dietitian and physical therapist for assessments, and completion of baseline questionnaires with study coordinator. * Adherence to daily physical function, dietary, and sleep recommendations and consumption of 5-day immunonutrition supplement. * Regular electronic/phone-call check-ins with study staff. * Telehealth appointment with physical therapist and dietitian prior to surgery. * After surgery and during hospital admission, final visit with dietitian and physical therapist for assessments, and completion of questionnaires. * 6-month follow-up period.
- interventionNames
- Behavioral: Prehabilitation Program
Primary outcomes (2)
- measure
- Enrollment Rate (Feasibility)
- timeFrame
- At screening
- description
- Number of eligible patients who enroll in study
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * 65 years of age and over * Adult male or non-pregnant female volunteers * Completed neoadjuvant chemotherapy or radiotherapy for esophageal cancer * At least four weeks to esophageal cancer surgery * Without skin conditions that preclude wearing sensors * Able to speak English and consent Exclusion Criteria: * Participants in any other interventional study that may bias results or limit study adherence during our study * Dietary restrictions that prevent consumption of nutritional supplements * Women who are pregnant, nursing, or at risk of becoming pregnant * Profound physical disability (for example, quadriplegia) that precludes participation in any aerobic or strength training.
References
Publications (0)
Data not yet available
No reference posted for this study.