Clinical trial · Interventional
Health Informatics and Resistance Exercise for Symptom Management and Quality of Life in Post-Esophagectomy Patients
Effects of Health Informatics for Symptom Management and Resistance Exercise Strategies on Quality of Life and Sarcopenia in Post-Esophagectomy Patients With Esophageal Cancer: A Mixed-Methods Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Participants are invited to take part in a research study. In accordance with the requirements of the health authorities, participants must be informed of the purpose of the study and its potential risks. Participation is voluntary, and each participant is free to decide whether or not to enroll. The study may be discussed with trusted individuals, and sufficient time may be taken to consider the decision. If any part of this consent form is unclear, questions may be directed to the principal investigator or the research team, who will provide an explanation. If a participant chooses not to participate, appropriate treatment will still be provided. Even if a participant agrees to participate initially, withdrawal is allowed at any time without affecting medical rights or the care that should be received.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Cancer (EsC) | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.85 |
| Quality of Life | — | UNRESOLVED | — |
| Sarcopenia | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| symptom management health informatics plus Resistance band exercise training | Behavioral | — | UNRESOLVED |
| Usual Care Group | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Usual Care Group
- description
- Participants receive standard postoperative nursing care and education as routinely provided by the clinical team. No additional interventions will be given.
- interventionNames
- Behavioral: Usual Care Group
- type
- EXPERIMENTAL
- label
- Symptom Management Health Informatics plus Resistance Exercise Group
- description
- Participants receive access to a symptom management health informatics program and a structured resistance band exercise training program.
- interventionNames
- Behavioral: symptom management health informatics plus Resistance band exercise training
Primary outcomes (1)
- measure
- Quality of Life (EORTC QLQ-C30 score)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18 years or older * Diagnosed with esophageal cancer and having undergone esophagectomy * Postoperative pathological report confirms R0 resection (complete tumor removal) * Able to be discharged after surgery * With or without adjuvant chemoradiotherapy * Clear consciousness and able to communicate in Mandarin or Taiwanese Exclusion Criteria: * Presence of severe cardiovascular disease or psychiatric disorders * Inability to communicate in Mandarin Chinese or Taiwanese * Disease progression during the intervention period that prevents continuation of participation.
References
Publications (3)
- RESULTChang YL, Tsai YF, Chao YK, Wu MY. Quality-of-life measures as predictors of post-esophagectomy survival of patients with esophageal cancer. Qual Life Res. 2016 Feb;25(2):465-475. doi: 10.1007/s11136-015-1094-4. Epub 2015 Aug 4. PMID 26238649
- RESULTChang YL, Tsai YF, Wu YC, Hsieh MJ. Factors relating to quality of life after esophagectomy for cancer patients in Taiwan. Cancer Nurs. 2014 Jan-Feb;37(1):4-13. doi: 10.1097/NCC.0b013e318277dc53. PMID 23357884
- RESULTChang YL, Tsai YF, Hsu CL, Chao YK, Hsu CC, Lin KC. The effectiveness of a nurse-led exercise and health education informatics program on exercise capacity and quality of life among cancer survivors after esophagectomy: A randomized controlled trial. Int J Nurs Stud. 2020 Jan;101:103418. doi: 10.1016/j.ijnurstu.2019.103418. Epub 2019 Sep 11. PMID 31670173