Clinical trial · Interventional
Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE）
Comparison of the Application Effects of Different Drainage Modes in the Perioperative Period of Minimally Invasive Three-Field Radical Esophagectomy for Esophageal Cancer
NCT07004634CI-TRIAL-00090779recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This RCT compares three drainage approaches after minimally invasive esophagectomy (chest tube + thoracic mediastinal drainage tube, thoracic, and abdominal mediastinal drainage tube) to evaluate perioperative outcomes, addressing current evidence gaps in pain and complication profiles.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Drainage/Methods | — | UNRESOLVED | — |
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
| Postoperative Pain | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Abdominal mediastinal tube | Procedure | — | UNRESOLVED |
| Chest mediastinal tube | Procedure | — | UNRESOLVED |
| Chest tube + chest mediastinal tube | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Abdominal mediastinal tube
- description
- Transperitoneal mediastinal drainage was performed for postoperative management of the patient.
- interventionNames
- Procedure: Abdominal mediastinal tube
- type
- EXPERIMENTAL
- label
- Chest mediastinal tube
- description
- Transthoracic mediastinal drainage was performed for postoperative management of the patient.
- interventionNames
- Procedure: Chest mediastinal tube
- type
- EXPERIMENTAL
- label
- Chest tube + chest mediastinal tube
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥18 years * Pathologically confirmed esophageal cancer requiring three-incision esophagectomy (cervical, thoracic, and abdominal incisions) * ASA physical status class I-III Exclusion Criteria: * History of chronic pain or long-term use of analgesics prior to surgery * Severe cardiopulmonary dysfunction (e.g., FEV1 \<50%) * Coagulation disorders or patients undergoing reoperation * Intraoperative findings of extensive pleural adhesions, combined resection of adjacent organs, or other conditions deemed by the investigator to warrant exclusion
References
Publications (0)
Data not yet available
No reference posted for this study.