Cancer
Malignant Colon Neoplasm
CI-CAN-00007995Explore in graph →
Top-level225 active trials5 approved drugs17 evidence items
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Cancer
CI-CAN-00007995Explore in graph →
Clinical trials
1,196 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (139)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07744139 | Radiogenomic Profiling of Dendritic Cells and Macrophages to Predict Recurrence in Colorectal Liver Metastasis(RaP-DMac-LiMe) | not yet recruiting | — | 210 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 0 | Aug 6, 2026 | clinicaltrials |
| NCT07059884 | Distance-Based Exercise to Preserve Function and Prevent Disability(DEFEND) | recruiting | N/A | 104 | Alliance for Clinical Trials in Oncology |
| 1 |
| Aug 5, 2026 |
| clinicaltrials |
| NCT02912559 | Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair | active not recruiting | Phase 3 | 712 | National Cancer Institute (NCI)NIH | 3 | Aug 4, 2026 | clinicaltrials |
| NCT06949111 | Radiotherapy + Systemic Therapy as Conversion Therapy for pMMR/MSS T4M0 Colon Cancer（Neo-Color） | recruiting | Phase 2 | 128 | Hebei Medical University Fourth HospitalOTHER | 1 | Aug 3, 2026 | clinicaltrials |
| NCT05715255 | Adaptive Symptom Self-Management Immunotherapy Study | active not recruiting | N/A | 400 | University of ArizonaOTHER | 1 | Jul 31, 2026 | clinicaltrials |
| NCT06458998 | Getting To Implementation: Improving Cancer Screening for Veterans(GTI) | enrolling by invitation | N/A | 30,300 | University of PittsburghOTHER | 1 | Jul 31, 2026 | clinicaltrials |
| NCT07733817 | Impact of Probiotics on Neuropathy Induced by Adjuvant Chemotherapy in Patients With Colon Cancer.(PROBIOCOL) | not yet recruiting | N/A | 130 | Centre Francois BaclesseOTHER | 1 | Jul 30, 2026 | clinicaltrials |
| NCT07732686 | Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry | not yet recruiting | — | 2,000 | University of OklahomaOTHER | 1 | Jul 29, 2026 | clinicaltrials |
| NCT01696981 | Screening for Colorectal Cancer in Older Patients (PLCO Screening Trial) | active not recruiting | N/A | 154,900 | National Cancer Institute (NCI)NIH | 1 | Jul 24, 2026 | clinicaltrials |
| NCT05394714 | A Phase I, Autologous ex Vivo Expanded and Activated NK Cell, Magicell-NK, Infusion for Colon Cancer Post Resection Study | recruiting | Phase 1 | 18 | Medigen Biotechnology CorporationINDUSTRY | 1 | Jul 24, 2026 | clinicaltrials |
| NCT05848739 | A Phase 1-2 of ST316 With Selected Advanced Unresectable and Metastatic Solid Tumors | active not recruiting | Phase 1 | 130 | Sapience TherapeuticsINDUSTRY | 1 | Jul 22, 2026 | clinicaltrials |
| NCT07720505 | COLOFLOW: Laser Speckle Contrast Imaging Versus Near-infrared Fluorescence Imaging With Indocyanine Green(COLOFLOW) | not yet recruiting | — | 30 | Leiden University Medical CenterOTHER | 0 | Jul 22, 2026 | clinicaltrials |
| NCT06215677 | Neoadjuvant Immunotherapy for T4 dMMR Colon Cancer(NITDC) | active not recruiting | Phase 2 | 18 | Peking Union Medical College HospitalOTHER | 1 | Jul 21, 2026 | clinicaltrials |
| NCT04599140 | SX-682 and Nivolumab for the Treatment of RAS-Mutated, MSS Unresectable or Metastatic Colorectal Cancer, the STOPTRAFFIC-1 Trial | active not recruiting | Phase 1 / Phase 2 | 51 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 20, 2026 | clinicaltrials |
| NCT06840977 | COLON ERDERLY LOW DOSE(CELOW) | recruiting | — | 51 | Matteo ClavarezzaOTHER | 1 | Jul 16, 2026 | clinicaltrials |
| NCT06927011 | Chronic Loose Stools Following Right-sided Hemicolectomy for Colon Cancer and the Association With Bile Acid Malabsorption and Small Intestinal Bacterial Overgrowth Using a Novel Sampling Device | recruiting | — | 20 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 16, 2026 | clinicaltrials |
| NCT06340646 | Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS) | recruiting | N/A | 990 | Washington University School of MedicineOTHER | 1 | Jul 14, 2026 | clinicaltrials |
| NCT07701408 | ctDNA and TEP Levels in Colon Cancer | not yet recruiting | N/A | 80 | Institute of Oncology LjubljanaOTHER | 1 | Jul 14, 2026 | clinicaltrials |
| NCT07697170 | Frequency of Care for Peripherally Inserted Central Vascular Access In the Prevention of Marsi(ICO-MARSI) | enrolling by invitation | N/A | 150 | Institut Català d'OncologiaOTHER | 1 | Jul 13, 2026 | clinicaltrials |
| NCT07691489 | A Study of Trastuzumab Deruxtecan (T-DXd) and Cetuximab in People With Colorectal Cancer | not yet recruiting | Phase 2 | 27 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jul 9, 2026 | clinicaltrials |
| NCT05308446 | Testing the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF Mutation | active not recruiting | Phase 2 | 86 | National Cancer Institute (NCI)NIH | 2 | Jul 8, 2026 | clinicaltrials |
| NCT07255729 | An Exosomal microRNA Signature for Preoperative Staging in Colon Cancer(EXPOSE) | recruiting | — | 400 | City of Hope Medical CenterOTHER | 1 | Jul 7, 2026 | clinicaltrials |
| NCT05710406 | Testing the Use of BRAF-Targeted Therapy After Surgery and Usual Chemotherapy for BRAF-Mutated Colon Cancer | active not recruiting | Phase 2 / Phase 3 | 1 | Alliance for Clinical Trials in OncologyOTHER | 1 | Jul 2, 2026 | clinicaltrials |
| NCT07186296 | EXoPERT EMERALD Clinical Study | recruiting | — | 1,400 | EXoPERTINDUSTRY | 1 | Jul 1, 2026 | clinicaltrials |
| NCT07595874 | Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3(NEST3) | recruiting | Phase 2 | 100 | City of Hope Medical CenterOTHER | 1 | Jul 1, 2026 | clinicaltrials |
| NCT02012699 | Integrated Cancer Repository for Cancer Research(iCaRe2) | recruiting | — | 999,999 | University of NebraskaOTHER | 1 | Jun 29, 2026 | clinicaltrials |
| NCT07673393 | Improving Prognostication in Colon Cancer(MARBLE) | not yet recruiting | — | 400 | Universitaire Ziekenhuizen KU LeuvenOTHER | 0 | Jun 29, 2026 | clinicaltrials |
| NCT07669454 | A Randomized, Double-blind, Placebo-controlled, Parallel-group, Comparative, Phase III Study to Evaluate the Efficacy and Safety of Nuvastatic® 300mg Capsule in Reducing Cancer-Tumor in Patients With Metastatic Colorectal Cancer Receiving Standard Chemotherapy.(NuvastaticTM) | recruiting | Phase 3 | 250 | Natureceuticals Sdn BhdINDUSTRY | 1 | Jun 25, 2026 | clinicaltrials |
| NCT07387263 | Mainstreaming Genetics: Evaluation of a Digital Application to Scale and Spread Oncologist-initiated Genetic Testing | recruiting | N/A | 180 | Unity Health TorontoOTHER | 1 | Jun 24, 2026 | clinicaltrials |
| NCT04678648 | A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies | recruiting | Phase 1 | 134 | RasCal Therapeutics, Inc.INDUSTRY | 1 | Jun 23, 2026 | clinicaltrials |
| NCT07198945 | Six Versus Twelve Month Index Follow-up After Large Colon Polyp Resection(STARLING) | enrolling by invitation | N/A | 546 | Indiana UniversityOTHER | 3 | Jun 17, 2026 | clinicaltrials |
| NCT05038254 | Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events | active not recruiting | N/A | 750 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 16, 2026 | clinicaltrials |
| NCT07649473 | QL1706 Combined With Standard Therapy for Conversion Therapy of Synchronous Liver Metastases From Colon Cancer: a Multicenter, Single-arm, Exploratory Study | not yet recruiting | Phase 2 | 30 | Fujian Medical UniversityOTHER | 1 | Jun 16, 2026 | clinicaltrials |
| NCT04616183 | LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer | active not recruiting | Phase 1 / Phase 2 | 46 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 12, 2026 | clinicaltrials |
| NCT05239546 | Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers(NAIO) | recruiting | Phase 2 | 25 | University of IowaOTHER | 1 | Jun 12, 2026 | clinicaltrials |
| NCT06051695 | A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression(EVEREST-2) | recruiting | Phase 1 / Phase 2 | 474 | A2 Biotherapeutics Inc.INDUSTRY | 1 | Jun 12, 2026 | clinicaltrials |
| NCT07011576 | A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)(FRUITFUL) | recruiting | Phase 2 | 60 | SCRI Development Innovations, LLCOTHER | 1 | Jun 12, 2026 | clinicaltrials |
| NCT07638956 | ICG in Colon Cancer(ICG) | not yet recruiting | N/A | 25 | Tanta UniversityOTHER | 0 | Jun 12, 2026 | clinicaltrials |
| NCT04017650 | Encorafenib, Cetuximab, and Nivolumab in Treating Patients With Microsatellite Stable, BRAFV600E Mutated Unresectable or Metastatic Colorectal Cancer | active not recruiting | Phase 1 / Phase 2 | 38 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 11, 2026 | clinicaltrials |
| NCT05283330 | Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors | recruiting | Phase 1 | 48 | Orano Med Theranostics, SASINDUSTRY | 1 | Jun 11, 2026 | clinicaltrials |
| NCT06446557 | De-scalation or swItch of Treatment According to Circulating tuMOr DNA Variation After 2 Cycles of Doublet Chemotherapy Plus Targeted Agent in Metastatic Unresectable Colorectal Cancer(DIAMOND) | not yet recruiting | Phase 3 | 408 | University Hospital, RouenOTHER | 1 | Jun 9, 2026 | clinicaltrials |
| NCT07132970 | Leakage Rate of Ileo-COlic Sutured Anastomosis After Right Hemicolectomy(LICOSARH) | recruiting | — | 249 | Aesculap AGINDUSTRY | 1 | Jun 9, 2026 | clinicaltrials |
| NCT07306390 | Distribution and Analysis of Metastatic Lymph Nodes in Colorectal Cancer Patients (DIAMOND)(DIAMOND) | not yet recruiting | — | 1,200 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Jun 9, 2026 | clinicaltrials |
| NCT00451022 | Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies | recruiting | — | 750 | National Cancer Institute (NCI)NIH | 1 | Jun 5, 2026 | clinicaltrials |
| NCT05056077 | Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit)(TTBF) | active not recruiting | N/A | 353 | University of California, San FranciscoOTHER | 1 | Jun 2, 2026 | clinicaltrials |
| NCT07319104 | Liquid Biopsy in Early Colorectal Lesions(FECCO-BioBank) | not yet recruiting | — | 1,000 | University Hospital, MontpellierOTHER | 1 | Jun 2, 2026 | clinicaltrials |
| NCT02572141 | FOLFOX or CAPOX Perioperative Chemotherapy Versus Postoperative Chemotherapy for Locally Advanced Colon Cancer (OPTICAL)(OPTICAL) | active not recruiting | Phase 3 | 738 | Sun Yat-sen UniversityOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT06890624 | mFOLFOXIRI Plus PD-1 Inhibitor vs mFOLFOX6 as Neoadjuvant Therapy for Locally Advanced Colon Cancer(OPTICAL-3) | not yet recruiting | Phase 2 | 138 | Sun Yat-sen UniversityOTHER | 0 | May 22, 2026 | clinicaltrials |
| NCT07596732 | Statewide Unified Network for Remote Intervention of Strength and Exercise(SUNRISE) | not yet recruiting | N/A | 120 | AdventHealth Translational Research InstituteOTHER | 0 | May 19, 2026 | clinicaltrials |
| NCT06043947 | Survival Monitoring in Russian Cancer Registries(SURVIMON) | active not recruiting | — | 100,000 | N.N. Petrov National Medical Research Center of OncologyOTHER | 1 | May 15, 2026 | clinicaltrials |
Data updated 22 days agoSource updated Aug 6, 2026source: clinicaltrials