Clinical trial · Interventional
Getting To Implementation: Improving Cancer Screening for Veterans
Getting To Implementation: Comparing the Effectiveness of Implementation Strategies to Improve Cancer Screening for Veterans
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Gastrointestinal cancers such as colon cancer and liver cancer cause many deaths in the US. Testing could catch these cancers early, helping people live longer. The goal of this study is to compare two different ways of getting more people tested for these cancers: 1) by directly reaching out to the people who need testing or 2) by helping providers fix issues that hold up testing. The main question it aims to answer is: how should healthcare systems go about choosing one or the other? Researchers will look at cancer testing rates over time at sites that are trying these different approaches. They will also survey and interview participants from these sites.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer of Colon | Malignant Colon Neoplasm | ALIAS | 0.90 |
| Cancer of Liver | Malignant Liver Neoplasm | ALIAS | 0.90 |
| Cirrhosis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Implementation Facilitation | Behavioral | — | UNRESOLVED |
| Patient Navigation | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Patient Navigation (PN)
- description
- Half of the HCC sites and half of the CRC sites will be randomized to PN.
- interventionNames
- Behavioral: Patient Navigation
- type
- ACTIVE_COMPARATOR
- label
- Implementation Facilitation (IF)
- description
- Half of the HCC sites and half of the CRC sites will be randomized to IF delivered by 2 facilitators (one clinical and one evaluation expert) per site.
- interventionNames
- Behavioral: Implementation Facilitation
Primary outcomes (2)
- measure
- Change in Reach of HCC screening from Baseline to 12 months
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Veterans: * ≥18 years of age * Enrolled in Veterans Health Administration (VA) * Have ≥1 VA encounter in the prior 18 months * Hepatocellular cancer (HCC) screening subgroup: Diagnosis of cirrhosis in electronic medical record * Colorectal cancer (CRC) screening subgroup: ≥45 years of age, positive fecal immunochemical test (FIT) (or other screening stool test) in the last 18 months 2. Providers: * Healthcare provider or related staff at participating VA site or engaged in CRC or HCC screening pathways in an included VA site (e.g., scheduling) * ≥18 years of age Exclusion Criteria: 1. Veterans: * \<18 years of age * Not enrolled in VA * No VA encounters in the prior 18 months * Limited life expectancy (\< 6 months), defined as having a code for hospice 2. Providers: * Members of the study team will not participate, even if their sites are recruited
References
Publications (1)
- DERIVEDRogal SS, Yakovchenko V, Morgan TR, Dominitz JA, McCurdy H, Nobbe A, Ekanem NR, Kang C, Gonzalez RI, Park A, Anwar J, Neely B, Gibson S, Lamorte C, Bajaj JS, Patton HM, Yao Y, Gawron AJ. Comparing the effectiveness of implementation strategies to improve liver and colon cancer screening for Veterans: protocol for a large cluster-randomized implementation study. Implement Sci. 2025 Aug 9;20(1):38. doi: 10.1186/s13012-025-01448-1. PMID 40783525