Clinical trial · Observational
Distribution and Analysis of Metastatic Lymph Nodes in Colorectal Cancer Patients (DIAMOND)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to learn about the spatial distribution and significance of metastatic lymph nodes in colorectal cancer patients. The main question it aims to answer is: * What is the spatial distribution pattern of metastatic lymph nodes in patients with colorectal cancer? * Can the spatial distribution pattern of metastatic lymph nodes in patients with colorectal cancer guide clinical practice? Participants should undergo regular follow-up examinations for at least 5 years after the surgery.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Colorectal Cancer Patients
Primary outcomes (1)
- measure
- The spatial distribution of metastatic lymph nodes
- timeFrame
- From enrollment to 14 days after surgery (at the completion of postoperative pathological examination)
Secondary outcomes (2)
- measure
- Disease-free survival
- timeFrame
- From date of surgery until the date of first documented local recurrence, distant metastasis, or date of death from any cause, whichever came first, assessed up to 60 months
- measure
- Overall survival
- timeFrame
- From date of surgery until the date of death from any cause, whichever came first, assessed up to 60 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Aged between 18 and 80 years * Pathologically confirmed adenocarcinoma of the colon or rectum * Underwent radical resection for colorectal cancer with a D3 lymphadenectomy and lymph nodes were submitted for pathological examination according to standardized station-based and distance-based protocol * No distant metastasis or distant metastasis within 6 months after surgery * No history of other malignant tumors or severe systemic diseases * No immune diseases or inflammatory bowel diseases * Non-emergency surgery * With complete clinicopathological and follow-up data Exclusion Criteria: * Pathologically confirmed benign tumors or non-adenocarcinoma malignancies * Underwent local excision or palliative resection * Regional lymph nodes were not dissected or submitted for pathological examination according to the unified station-based or distance-based protocol * With distant metastasis or distant metastasis within 6 months after surgery * Dual or multiple primary colorectal cancers or concurrent other malignant tumors * Had a previous diagnosis of immune diseases or inflammatory bowel disease such as ulcerative colitis or Crohn's disease * Underwent emergency surgery * Had incomplete clinicopathological or follow-up data
References
Publications (0)
Data not yet available