Cancer
Malignant Colon Neoplasm
CI-CAN-00007995Explore in graph →
Top-level225 active trials5 approved drugs17 evidence items
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Cancer
CI-CAN-00007995Explore in graph →
Genomics
6 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
461 cases with simple somatic mutation data · 461 cases total · Data Release 46.0 · mapped to Colon Adenocarcinoma ONTOLOGY_EXACT
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | ZNF831 | Ssm | 348 | 461 | 75.5% | gdc |
| 2 | PTPRT | Ssm | 348 | 461 | 75.5% | gdc |
| 3 | DIDO1 | Ssm | 345 | 461 | 74.8% | gdc |
| 4 | KCNB1 | Ssm | 343 | 461 | 74.4% | gdc |
| 5 | APC | Ssm | 341 | 461 | 74% | gdc |
| 6 | LAMA5 | Ssm | 340 | 461 | 73.8% | gdc |
| 7 | CHD6 | Ssm | 339 | 461 | 73.5% | gdc |
| 10 | TSHZ2 | Ssm |
Data updated 22 days agoSource updated Data Release 46.0
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 338 |
| 461 |
| 73.3% |
| gdc |
| 8 | ZMYND8 | Ssm | 338 | 461 | 73.3% | gdc |
| 9 | SLC12A5 | Ssm | 338 | 461 | 73.3% | gdc |
| 12 | CDH4 | Ssm | 337 | 461 | 73.1% | gdc |
| 11 | RALGAPB | Ssm | 337 | 461 | 73.1% | gdc |
| 13 | NCOA6 | Ssm | 336 | 461 | 72.9% | gdc |
| 14 | ARFGEF2 | Ssm | 336 | 461 | 72.9% | gdc |
| 15 | ZNFX1 | Ssm | 335 | 461 | 72.7% | gdc |
| 21 | DDX27 | Ssm | 334 | 461 | 72.5% | gdc |
| 18 | SYCP2 | Ssm | 334 | 461 | 72.5% | gdc |
| 16 | ASXL1 | Ssm | 334 | 461 | 72.5% | gdc |
| 20 | ZNF335 | Ssm | 334 | 461 | 72.5% | gdc |
| 19 | CEP250 | Ssm | 334 | 461 | 72.5% | gdc |
| 17 | KCNQ2 | Ssm | 334 | 461 | 72.5% | gdc |
| 22 | KIAA1755 | Ssm | 333 | 461 | 72.2% | gdc |
| 24 | SALL4 | Ssm | 332 | 461 | 72% | gdc |
| 26 | GNAS | Ssm | 332 | 461 | 72% | gdc |
| 23 | HELZ2 | Ssm | 332 | 461 | 72% | gdc |
| 25 | PREX1 | Ssm | 332 | 461 | 72% | gdc |
| 28 | ATP9A | Ssm | 331 | 461 | 71.8% | gdc |
| 29 | PLCG1 | Ssm | 331 | 461 | 71.8% | gdc |
| 30 | TGM2 | Ssm | 331 | 461 | 71.8% | gdc |
| 27 | MYH7B | Ssm | 331 | 461 | 71.8% | gdc |