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Malignancy in Giant Cell Tumor of Bone · CancerIndex

Cancers
Neoplasm
Neoplasm by Special Category
Malignant Neoplasm
Sarcoma
Bone Sarcoma
Malignancy in Giant Cell Tumor of Bone

Subtype

Malignancy in Giant Cell Tumor of Bone

CI-CAN-00003135Explore in graph →

1 active trials

NCIt: C4304

Overview
Statistics
Survival
Genomics
Variants & evidence
Drugs
Trials1
Research
Rankings
Sources & provenance

Data completeness2 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (no data yet)
Evidence (no data yet)
Therapies (no data yet)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A malignant tumor that arises from the bone. It is characterized by the presence of an area of high grade sarcoma in an otherwise typical giant cell tumor (primary malignancy in giant cell tumor), or the presence of sarcoma in which the pre-existing giant cell tumor may or may not be apparent (secondary malignancy in giant cell tumor).

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Bone SarcomaSubtype
Malignant Osteoclastic Giant Cell-Rich Tumor of BoneSubtype

Children (0)

Leaf node — no children.

Anatomy

Anatomical sites

Connective and Soft TissueC3810

Record

Identity

CancerIndex ID: CI-CAN-00003135
Entity type: Subtype
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 5
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active): 1 / 1

Publications (all / 5y)

67 / 24

Evidence items

0

Genes / variants

0 / 0

Drugs (any / approved)

0 / 0

Genomic cohorts

0

Epidemiology / survival obs.

0 / 0

Data updated 13 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (8)

Dedifferentiated Giant Cell Tumorsynonym · NCIt
Giant Cell Bone Sarcomasynonym · NCIt
Giant Cell Sarcoma of Bonesynonym · NCIt
Giant Cell Sarcoma of the Bonesynonym · NCIt
Giant cell tumor of bone, malignantsynonym · NCIt
Malignancy in Giant Cell Tumor of the Bonesynonym · NCIt
Malignant Giant Cell Tumor of Bonesynonym · NCIt
OSTEOCLASTOMA, MALIGNANTsynonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

No registry-level ancestor: burden figures are published for the mutually exclusive top-level site groups only, and this entity does not descend from one. Global figures (IARC / GLOBOCAN) stay under license review and SEER awaits credentials.

Active trials1countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #1186 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials0countstatus RECRUITING · entity + descendantsclinicaltrialsComputednot in a current ranking snapshot
Curated evidence items0countaccepted CIViC items · entity + descendantscivicComputednot in a current ranking snapshot
Publications, last 12 months3countPubMed records · stored query · 12-month windowpubmedComputedrank #1485 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts0countopen GDC projects · entity + descendantsgdcComputednot in a current ranking snapshot

Data updated 13 hours agoSource updated unknownregistry figures: none · counters aggregate over descendants