Subtype
Lung Small Cell Carcinoma
CI-CAN-00005832SCLCExplore in graph →
381 active trials6 approved drugs6 evidence items
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Subtype
CI-CAN-00005832SCLCExplore in graph →
Clinical trials
1,100 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (157)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03219762 | Study of Nab-paclitaxel in Sensitive and Refractory Relapsed SCLC(Nabster) | unknown | Phase 2 | 65 | Gruppo Oncologico Italiano di Ricerca ClinicaOTHER | 1 | Jul 26, 2017 | clinicaltrials |
| NCT01575782 | Chloroquine as an Anti-autophagic Radiosensitizing Drug in Stage I-III Small Cell Lung Cancer(Chloroquine) | terminated | Phase 1 | 5 | Maastricht Radiation OncologyOTHER | 1 | Jul 18, 2017 |
| clinicaltrials |
| NCT00856830 | Bendamustine With Irinotecan Followed by Etoposide/Carboplatin for Patients With Extensive Stage Small Cell Lung Cancer | completed | Phase 1 / Phase 2 | 30 | University of Alabama at BirminghamOTHER | 1 | Jul 17, 2017 | clinicaltrials |
| NCT00454324 | Study of Abraxane and Carboplatin to Treat Small Cell Lung Cancer(NRR) | terminated | Phase 2 | 30 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Jul 11, 2017 | clinicaltrials |
| NCT00958022 | Carboplatin and Etoposide Plus LBH589 for Small Cell Lung Cancer | terminated | Phase 1 | 7 | Ahmad TarhiniOTHER | 1 | Jun 22, 2017 | clinicaltrials |
| NCT00043862 | The Study Of An Oral Drug Called A Radiation Sensitizer In Patients With Newly Diagnosed Small Cell Lung Cancer (SCLC)((SCLC)) | completed | Phase 2 | 60 | GlaxoSmithKlineINDUSTRY | 1 | May 31, 2017 | clinicaltrials |
| NCT00046111 | A Bioequivalence Study of Two Oral Formulations of Topotecan in Patients With Advanced Solid Tumors | completed | Phase 1 | 1 | GlaxoSmithKlineINDUSTRY | 2 | May 30, 2017 | clinicaltrials |
| NCT01166191 | Concurrent Chemo-radiotherapy With Intensity-Modulated Radiation Therapy (IMRT) for Limited Disease Small Cell Lung Cancer (LD-SCLC) | completed | Phase 2 | 60 | Maastricht Radiation OncologyOTHER | 1 | May 23, 2017 | clinicaltrials |
| NCT02567396 | Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction | withdrawn | Phase 1 | 0 | National Cancer Institute (NCI)NIH | 0 | Apr 24, 2017 | clinicaltrials |
| NCT01719861 | Phase 2a Desipramine in Small Cell Lung Cancer and Other High-Grade Neuroendocrine Tumors | terminated | Phase 2 | 6 | Joel NealOTHER | 1 | Apr 17, 2017 | clinicaltrials |
| NCT02577627 | Multi-Indication, Retrospective Oncological Study to Validate the Accuracy in Predicting TTP by PrediCare in Patients Under SOC | unknown | — | 5,000 | Optimata Ltd.INDUSTRY | 1 | Apr 4, 2017 | clinicaltrials |
| NCT00883181 | A Study of Neutropenia and Anemia Management in Patients With Solid Tumors Receiving Myelotoxic Chemotherapy | completed | — | 1,370 | AmgenINDUSTRY | 0 | Mar 15, 2017 | clinicaltrials |
| NCT00320359 | Topotecan Plus Cisplatin Versus Etoposide Plus Cisplatin In 1st Line Extensive Disease Small Cell Lung Cancer | completed | Phase 3 | 700 | GlaxoSmithKlineINDUSTRY | 2 | Mar 1, 2017 | clinicaltrials |
| NCT01640847 | MRI Guided High Intensity Focused Ultrasound (HIFU) and ThermoDox for Palliation of Painful Bone Metastases | withdrawn | Phase 2 | 0 | ImunonINDUSTRY | 0 | Feb 7, 2017 | clinicaltrials |
| NCT03029858 | PD-L1 and Other Immuno-markers Influenced by Osimertinib Treatment in Advanced NSCLC Patients(ATHENE) | unknown | — | 155 | Guangdong Association of Clinical TrialsOTHER | 1 | Jan 24, 2017 | clinicaltrials |
| NCT01173458 | Circulating Tumor Cells (CTCs) as a Blood-based Tumor Marker in Patients With Small Cell Lung Cancer (SCLC) | completed | — | 25 | University of Kansas Medical CenterOTHER | 1 | Jan 10, 2017 | clinicaltrials |
| NCT02661100 | A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patients | withdrawn | Phase 1 / Phase 2 | 0 | Case Comprehensive Cancer CenterOTHER | 0 | Dec 7, 2016 | clinicaltrials |
| NCT02348450 | Irinotecan Plus Cisplatin Compared With Etoposide Plus Cisplatin for Extensive Stage Small-cell Lung Cancer | unknown | Phase 4 | 308 | Guangdong Association of Clinical TrialsOTHER | 1 | Dec 5, 2016 | clinicaltrials |
| NCT02980809 | Topotecan Plus Apatinib Versus Topotecan Alone as Second-line Therapy in Small-cell Lung Cancer | unknown | Phase 2 | 60 | First Hospitals affiliated to the China PLA General HospitalOTHER_GOV | 0 | Dec 2, 2016 | clinicaltrials |
| NCT02972320 | Extensive Stage Sclc Patients Who Were Benefit From First-line Treatment Accept Temozolomide Maintain Therapeutic | unknown | Phase 2 | 60 | Yunpeng LiuOTHER | 1 | Nov 23, 2016 | clinicaltrials |
| NCT02906384 | Memory and MRI Changes With Hippocampus Avoidance Prophylactic Cranial Irradiation(HA-PCI) for Small Cell Lung Cancer(SCLC) | unknown | Phase 2 | 154 | Zhejiang Cancer HospitalOTHER | 1 | Oct 10, 2016 | clinicaltrials |
| NCT01829971 | A Multicenter Phase I Study of MRX34, MicroRNA miR-RX34 Liposomal Injection | terminated | Phase 1 | 155 | Mirna Therapeutics, Inc.INDUSTRY | 2 | Sep 27, 2016 | clinicaltrials |
| NCT00144989 | A Study Comparing Irinotecan and Cisplatin (IP) With Etoposide and Cisplatin (EP) Following EP/TRT for LD-SCLC | completed | Phase 3 | 281 | Haruhiko FukudaOTHER | 1 | Sep 22, 2016 | clinicaltrials |
| NCT01221675 | TF2- Small Cell Lung Cancer Radio Immunotherapy | completed | Phase 1 / Phase 2 | 18 | Centre René GauducheauOTHER | 1 | Aug 31, 2016 | clinicaltrials |
| NCT02875457 | Apatinib as the Maintenance Therapy for Extensive Stage Small Cell Lung Cancer After Combined With Etoposide/Cisplatin | unknown | Phase 3 | 100 | Third Military Medical UniversityOTHER | 0 | Aug 24, 2016 | clinicaltrials |
| NCT00580320 | Safety Study of Dacarbazine and Bortezomib in Melanoma and Soft Tissue Sarcoma | completed | Phase 1 | 17 | Virginia Commonwealth UniversityOTHER | 1 | Aug 18, 2016 | clinicaltrials |
| NCT01045421 | Alisertib in Adults With Nonhematological Malignancies, Followed by Alisertib in Lung, Breast, Head and Neck or Gastroesophageal Malignancies | completed | Phase 1 / Phase 2 | 273 | Millennium Pharmaceuticals, Inc.INDUSTRY | 1 | Aug 15, 2016 | clinicaltrials |
| NCT01137162 | Clinical and Pathologic Studies of Patients Undergoing Treatment With EGFR Inhibitors | terminated | — | 10 | Stanford UniversityOTHER | 1 | Jul 22, 2016 | clinicaltrials |
| NCT00682981 | A Phase I/II Study of Carboplatin and Etoposide With or Without Obatoclax in Extensive-stage Small Cell Lung Cancer (ES-SCLC) | completed | Phase 1 / Phase 2 | 218 | Gemin XINDUSTRY | 10 | Jul 21, 2016 | clinicaltrials |
| NCT02152059 | A Study to Evaluate the Good and Bad Effects of BIBF1120 in Small Cell Lung Cancer Patients Who Have Previously Benefited From First-line Platinum-based Chemotherapy | withdrawn | Phase 2 | 0 | AHS Cancer Control AlbertaOTHER | 1 | Jul 6, 2016 | clinicaltrials |
| NCT01182155 | Breath Analysis for Evaluation of Radiation Exposure in Lung Cancer Patients Treated With Radiation | completed | — | 20 | Stanford UniversityOTHER | 1 | Jul 1, 2016 | clinicaltrials |
| NCT01155258 | Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors | completed | Phase 1 | 19 | University of Southern CaliforniaOTHER | 1 | Jun 13, 2016 | clinicaltrials |
| NCT02105168 | Identification of Marker of Primary or Acquired Resistance to Anti Tumorous Treatment(MSN) | unknown | N/A | 2,200 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 1 | Jun 10, 2016 | clinicaltrials |
| NCT01745445 | Clinical Randomized Study of Concurrent Chemo-radiotherapy vs Radiotherapy Alone to Local-advanced Small Cell Lung Cancer (SCLC)(SCLC) | unknown | Phase 2 | 30 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | May 17, 2016 | clinicaltrials |
| NCT02772107 | Temozolomide as Maintenance Therapy Following Induction Chemotherapy in Extensive Stage Small Cell Lung Cancer | unknown | Phase 2 / Phase 3 | 132 | Chinese PLA General HospitalOTHER | 1 | May 17, 2016 | clinicaltrials |
| NCT02351505 | Selinexor in Treating Patients With Relapsed Small Cell Lung Cancer | terminated | Phase 2 | 1 | Erin BertinoOTHER | 1 | May 16, 2016 | clinicaltrials |
| NCT01076504 | A Trial of Amrubicin and Carboplatin With Pegfilgrastim in Patients With Extensive-Stage Small Cell Lung Cancer | completed | Phase 2 | 81 | SCRI Development Innovations, LLCOTHER | 1 | May 5, 2016 | clinicaltrials |
| NCT02738346 | SCLC on the 2nd Line With Relapsed After Response to Chemotherapy GFPC 01-2013(CBPC) | unknown | Phase 3 | 164 | University Hospital, AngersOTHER_GOV | 1 | Apr 25, 2016 | clinicaltrials |
| NCT01331525 | The Addition of Ipilimumab to Carboplatin and Etoposide Chemotherapy for Extensive Stage Small Cell Lung Cancer(ICE) | completed | Phase 2 | 42 | University Hospital Southampton NHS Foundation TrustOTHER | 1 | Apr 14, 2016 | clinicaltrials |
| NCT02738723 | SBRT Compared With IMRT Concurrently With Chemotherapy in Treating Patients With LS-SCLC | unknown | Phase 2 | 50 | Third Military Medical UniversityOTHER | 1 | Apr 14, 2016 | clinicaltrials |
| NCT02736916 | HS-WBRT for Prophylactic Cranial Irradiation in Limited Stage Small Cell Lung Cancer | unknown | N/A | 3 | General Hospital of Ningxia Medical UniversityOTHER | 1 | Apr 13, 2016 | clinicaltrials |
| NCT01977235 | Two Different Dosages of Irinotecan Combined With Cisplatin Scheme in Extensive Disease-Small Cell Lung Cancer(TDICC) | unknown | Phase 2 | 110 | Third Military Medical UniversityOTHER | 1 | Apr 1, 2016 | clinicaltrials |
| NCT00930891 | Bevacizumab in Extensive Small Cell Lung Cancer(CPC) | completed | Phase 2 / Phase 3 | 143 | Intergroupe Francophone de Cancerologie ThoraciqueOTHER | 1 | Mar 10, 2016 | clinicaltrials |
| NCT00643396 | Phase II Trial of Consolidative Thoracic Radiotherapy for Extensive Stage Small Cell Lung Cancer | completed | Phase 2 | 30 | AHS Cancer Control AlbertaOTHER | 1 | Feb 26, 2016 | clinicaltrials |
| NCT02688673 | DC Vaccine Combined With CIK Cells in Patients With SCLC | unknown | Phase 1 / Phase 2 | 30 | Affiliated Hospital to Academy of Military Medical SciencesOTHER | 0 | Feb 23, 2016 | clinicaltrials |
| NCT01784107 | A Phase Ib/II Trial of Belotecan and Ifosfamide in Patients With Extensive Disease of Small Cell Lung Cancer | unknown | Phase 1 / Phase 2 | 45 | Gachon University Gil Medical CenterOTHER | 1 | Feb 10, 2016 | clinicaltrials |
| NCT00812266 | Topotecan and Cisplatin Versus Etoposide and Carboplatin in 1st Line Treatment of Patients With Small Cell Lung Cancer and Extensive Disease (SCLC-ED) | terminated | Phase 3 | 281 | Danish Oncological Lung Cancer GroupOTHER | 1 | Jan 26, 2016 | clinicaltrials |
| NCT00401609 | G-Step: Gemcitabine Based Small-cell Lung Cancer Treatment in Elderly Patients(G-Step) | completed | Phase 1 / Phase 2 | 85 | National Cancer Institute, NaplesOTHER | 1 | Jan 14, 2016 | clinicaltrials |
| NCT01533181 | Linsitinib or Topotecan Hydrochloride in Treating Patients With Relapsed Small Cell Lung Cancer | completed | Phase 2 | 44 | National Cancer Institute (NCI)NIH | 2 | Jan 14, 2016 | clinicaltrials |
| NCT00299390 | Safety and Efficacy Study of a New Chemotherapy Agent to Treat Small Cell Lung Cancer | terminated | Phase 2 | 10 | BayerINDUSTRY | 0 | Dec 31, 2015 | clinicaltrials |
Data updated 23 days agoSource updated Jul 26, 2017source: clinicaltrials