Liposarcoma

In a phase 2 clinical trial, NCT01209598, 30 patients with CDK4-amplified and RB-expressing well differentiated and dedifferentiated liposarcomas (WDLS/DDLS) were treated with a selective CDK 4/6 inhi… (full text at CIViC)

PMID 23569312 · Dickson et al., 2013 · Open in CIViC

A total of 59 patients with well-differentiated or dedifferentiated liposarcomas were enrolled in a phase 2 study to evaluate palbociclib efficacy. Half of the patients had received prior treatment an… (full text at CIViC)

PMID 27124835 · Dickson et al., 2016 · Open in CIViC

In the phase II trial (NCT02992743) of letetresgene autoleucel (lete-cel) in human leukocyte antigen ((HLA)-A*02:01–, HLA-A*02:05–, and/or HLA-A*02:06–positive), NY-ESO-1 (CTAG1B)-expressing advanced … (full text at CIViC)

PMID 39836945 · D'Angelo et al., 2025 · Open in CIViC

Both RT-PCR and PCR were used to detect and confirm the presence of fusion transcripts in RNA extracted from the surgical resections of 74 liposarcomas and 98 lipomas. EWSR1-DDIT3 (EWS-CHOP) was foun… (full text at CIViC)

PMID 20332486 · Kubo et al., 2010 · Open in CIViC

Identified two cases of myxoid liposarcoma with translocations (between 12q13 and 22q12) giving rise to EWSR1-DDIT3 (EWS-CHOP) fusions instead of the more common FUS-DDIT3.

PMID 8637704 · Panagopoulos et al., 1996 · Open in CIViC

Both RT-PCR and PCR were used to detect and confirm the presence of fusion transcripts in RNA extracted from the surgical resections of 74 liposarcomas and 98 lipomas. FUS-DDIT3 (TLS-CHOP) was found … (full text at CIViC)

PMID 20332486 · Kubo et al., 2010 · Open in CIViC

In this 1992 paper, 9 of 26 liposarcoma patients had a histopathologic diagnosis of myxoid liposarcoma. Cytogenetic analysis revealed 6 of these patients had t(12;16)(q13;p11). 2 patients had a cyt… (full text at CIViC)

PMID 1568170 · Sreekantaiah et al., 1992 · Open in CIViC

Both RT-PCR and PCR were used to detect and confirm the presence of fusion transcripts in RNA extracted from the surgical resections of 74 liposarcomas and 98 lipomas. HMGA2-LPP was found in 19/98 (19… (full text at CIViC)

PMID 20332486 · Kubo et al., 2010 · Open in CIViC

Both RT-PCR and PCR were used to detect and confirm the presence of fusion transcripts in RNA extracted from the surgical resections of 74 liposarcomas and 98 lipomas. LPP-HMGA2 or HMGA2-LPP fusions w… (full text at CIViC)

PMID 20332486 · Kubo et al., 2010 · Open in CIViC

In 41 patients with postbaseline scans, three patients with liposarcoma achieved a partial response (at 250, 400, and 500 mg), 31 showed stable disease, and eight had progressive disease. In total, 27… (full text at CIViC)

PMID 28240971 · Wagner et al., 2017 · Open in CIViC