Variant · Fusion
DDIT3 Fusion
CI-VAR-00001198Explore in graph →CIViC 717
Curated evidence
Evidence by cancer (3 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 20332486
- Run
- ING-CIVIC-20260908-000001
| Molecular profile | Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| Dedifferentiated Liposarcoma1 | ||||||||
| EWSR1::DDIT3 Fusion | (diagnostic) | Diagnostic | C | Supports Positive | 1 | submitted | EID11520Both RT-PCR and PCR were used to detect and confirm the presence of fusion transcripts in RNA extracted from the surgical resections of 74 liposarcomas and 98 lipomas. EWSR1::DDIT3 (EWS-CHOP) was foun… (full text at CIViC) PMID 20332486 · Kubo et al., 2010 · Open in CIViC | civic |
| Liposarcoma1 | ||||||||
| EWSR1::DDIT3 Fusion | (diagnostic) | Diagnostic | B | Supports Positive | 3 | submitted | EID7982Both RT-PCR and PCR were used to detect and confirm the presence of fusion transcripts in RNA extracted from the surgical resections of 74 liposarcomas and 98 lipomas. EWSR1-DDIT3 (EWS-CHOP) was foun… (full text at CIViC) PMID 20332486 · | |
ClinVar
Clinical significance (0)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
Data not yet available