LPP Fusion

CI-VAR-00001284Explore in graph →CIViC 2969

Curated evidence

Evidence by cancer (2 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–2 of 2 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Liposarcoma2
HMGA2::LPP Fusion	(diagnostic)	Diagnostic	B	Supports Negative	4	rejected	EID7984 Both RT-PCR and PCR were used to detect and confirm the presence of fusion transcripts in RNA extracted from the surgical resections of 74 liposarcomas and 98 lipomas. HMGA2-LPP was found in 19/98 (19… (full text at CIViC) PMID 20332486 · Kubo et al., 2010 · Open in CIViC	civic
LPP::HMGA2 Fusion OR HMGA2::LPP Fusion	(diagnostic)	Diagnostic	B	Supports Negative	4	accepted	EID7983 Both RT-PCR and PCR were used to detect and confirm the presence of fusion transcripts in RNA extracted from the surgical resections of 74 liposarcomas and 98 lipomas. LPP-HMGA2 or HMGA2-LPP fusions w… (full text at CIViC) PMID 20332486 · Kubo et al., 2010 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.