Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,846 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,846 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01885702 | Dendritic Cell Vaccination in Patients With Lynch Syndrome or Colorectal Cancer With MSI | unknown | Phase 1 / Phase 2 | 25 | Radboud University Medical CenterOTHER | 1 | Apr 4, 2025 | clinicaltrials |
| NCT06440018 | INSPIRE: a Multi-Cancer Early Detection Study(INSPIRE) | unknown | — | 5,350 | Singlera Genomics Inc.INDUSTRY | 1 | Feb 21, 2025 | clinicaltrials |
| NCT06562140 | Multidimensional Examination of Patients with Colorectal and Anal Cancer(MECACP) | unknown | — | 300 | University of PecsOTHER | 1 | Jan 23, 2025 | clinicaltrials |
| NCT06216743 | PRE- MISTIC: MRI and Cine Imaging to Improve Staging of Tumors in the Colon(PRE-MISTIC) | unknown | N/A | 15 | Radboud University Medical CenterOTHER | 1 | Dec 31, 2024 | clinicaltrials |
| NCT04660929 | CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors | unknown | Phase 1 | 48 | Carisma Therapeutics IncINDUSTRY | 1 | Dec 18, 2024 | clinicaltrials |
| NCT06646809 | Reducing Inflammatory Syndrome in Surgery - Colorectal (RISIS-CR) Trial(RISIS-CR) | unknown | Phase 3 | 80 | National University Hospital, SingaporeOTHER | 1 | Oct 17, 2024 | clinicaltrials |
| NCT06344923 | Peritoneum and Anterior Rectus Sheath Suturing and Ileostomy | unknown | N/A | 120 | Qilu Hospital of Shandong UniversityOTHER | 1 | Oct 16, 2024 | clinicaltrials |
| NCT04913337 | Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies | unknown | Phase 1 / Phase 2 | 179 | NGM Biopharmaceuticals, IncINDUSTRY | 3 | Oct 2, 2024 | clinicaltrials |
| NCT06403709 | Irinotecan, TAS-102 Plus Bevacizumab as a Third-Line or Beyond Therapy in mCRC Patients | unknown | Phase 2 | 35 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Sep 24, 2024 | clinicaltrials |
| NCT03018418 | Proton Therapy in Reducing Toxicity in Anal Cancer | unknown | Phase 2 | 14 | Jordan KharofaOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT06210724 | FIT in Diverticulitis | unknown | — | 275 | Royal Surrey County Hospital NHS Foundation TrustOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT06587152 | Clinical Trial to Evaluate the Efficacy and Safety of a Thoracic and Abdominal Endoscopic Surgical System | unknown | N/A | 60 | Cornerstone RoboticsINDUSTRY | 1 | Sep 19, 2024 | clinicaltrials |
| NCT06575127 | Modified FOLFOXIRI Plus Target Therapy as a First Line Treatment for Advanced Colorectal Cancer a Prospective Phase Two Study | unknown | Phase 2 | 60 | Al-Azhar UniversityOTHER | 1 | Aug 28, 2024 | clinicaltrials |
| NCT05381792 | Serial Gut Microbiome and Bacterial Gene Markers Changes After Endoscopic Resection of Colorectal Advanced Neoplasia(M3-CAN) | unknown | — | 50 | Chinese University of Hong KongOTHER | 1 | Aug 27, 2024 | clinicaltrials |
| NCT05867303 | A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors | unknown | Phase 1 | 48 | RemeGen Co., Ltd.INDUSTRY | 2 | Aug 16, 2024 | clinicaltrials |
| NCT05385250 | Bone-sparing Chemoradiotherapy for Anal Cancer - DACG-II(DACG-II) | unknown | N/A | 100 | Karen-Lise Garm SpindlerOTHER | 1 | Aug 15, 2024 | clinicaltrials |
| NCT06540027 | The Effect of Minimally Invasive Surgery on Systemic Inflammatory Response in Rectal Cancer | unknown | — | 80 | Başakşehir Çam & Sakura City HospitalOTHER_GOV | 1 | Aug 15, 2024 | clinicaltrials |
| NCT05570279 | PLAN-A Data- Bio- and Plan- Bank Collection for SCCA in Denmark(PLAN-A) | unknown | — | 314 | Aarhus University HospitalOTHER | 1 | Aug 14, 2024 | clinicaltrials |
| NCT06006390 | CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors | unknown | Phase 1 / Phase 2 | 60 | Chongqing Precision Biotech Co., LtdINDUSTRY | 1 | Aug 9, 2024 | clinicaltrials |
| NCT06259149 | A Study of Initiation Timing of VTE Prevention After Colorectal Cancer Surgery | unknown | — | 914 | RenJi HospitalOTHER | 1 | Aug 9, 2024 | clinicaltrials |
| NCT06339346 | Analysis of Histopathological Factors Predictive of Lymph Node Involvement and Management Practices in pT1 Colorectal Cancers Treated by Primary Endoscopic Resection(PROMOT1) | unknown | — | 400 | University Hospital, BrestOTHER | 1 | Aug 9, 2024 | clinicaltrials |
| NCT06341309 | Exploratory Study of Irinotecan Liposomes in Maintenance Therapy of Metastatic Colorectal Cancer | unknown | Phase 1 / Phase 2 | 20 | West China HospitalOTHER | 0 | Aug 9, 2024 | clinicaltrials |
| NCT06540430 | Digital Based Home Care Service for Ostomy Patients | unknown | N/A | 120 | Wonju Severance Christian HospitalOTHER | 0 | Aug 9, 2024 | clinicaltrials |
| NCT06543836 | ctDNA-guided Treatment of TKI Plus PD-1 Inhibitor for Advanced pMMR/MSS Colorectal Cancer | unknown | Phase 2 | 68 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Aug 9, 2024 | clinicaltrials |
| NCT06545630 | Tumor Antigen-sensitized DC Vaccine for Colorectal Cancer Liver Metastases | unknown | Phase 1 | 10 | West China HospitalOTHER | 1 | Aug 9, 2024 | clinicaltrials |
| NCT02991677 | Exercise Effect on Chemotherapy-Induced Neuropathic Pain | unknown | N/A | 60 | Baltimore VA Medical CenterFED | 1 | Aug 6, 2024 | clinicaltrials |
| NCT04636008 | Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer | unknown | Phase 1 / Phase 2 | 20 | West China HospitalOTHER | 1 | Aug 6, 2024 | clinicaltrials |
| NCT04716257 | A Prospective, Multi-center, Real-world Study of Ovarian Metastatic Colorectal Cancer Patients(proOMCRC) | unknown | — | 400 | West China HospitalOTHER | 1 | Aug 6, 2024 | clinicaltrials |
| NCT06536712 | Effects of Exosome Adminstration in Preventing Early Leakage in Rectal Cancer Patients Undergoing Low Anterior Resection | unknown | Phase 1 | 20 | Tehran University of Medical SciencesOTHER | 1 | Aug 5, 2024 | clinicaltrials |
| NCT04149613 | Predictive and Prognostic Value of Inflammatory Markers and microRNA in Stage IV Colorectal Cancer | unknown | — | 100 | American University of Beirut Medical CenterOTHER | 1 | Jul 31, 2024 | clinicaltrials |
| NCT06528054 | TreatmENT of AnastomotiC LeakagE After COLON Cancer Resection(TENTACLE-Colon) | unknown | — | 2,000 | Radboud University Medical CenterOTHER | 0 | Jul 30, 2024 | clinicaltrials |
| NCT06524362 | Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Trial(PERECARE) | unknown | N/A | 77 | GEM Hospital & Research CenterOTHER | 1 | Jul 29, 2024 | clinicaltrials |
| NCT06519006 | Effectiveness of Pelvic Floor Exercise to Prevent LARS (Low Anterior Resection Syndrome)(CH1) | unknown | N/A | 50 | F. D. Roosevelt University HospitalOTHER | 1 | Jul 25, 2024 | clinicaltrials |
| NCT05883683 | Molecular Study and Precision Medicine for Colorectal Cancer(MSPM) | unknown | — | 100 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Jul 24, 2024 | clinicaltrials |
| NCT06256055 | Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors | unknown | Phase 1 | 24 | UTC Therapeutics Inc.INDUSTRY | 1 | Jul 24, 2024 | clinicaltrials |
| NCT06516445 | SCRT Followed by Camrelizumab Combined With Fluzoparib and Chemotherapy as Neoadjuvant Therapy for LARC | unknown | Phase 2 | 33 | Huazhong University of Science and TechnologyOTHER | 1 | Jul 24, 2024 | clinicaltrials |
| NCT06513481 | A Study of Enhancing Drug Prophylaxis of Venous Thromboembolism in Chinese Colorectal Cancer Surgery(E-DISTANCE) | unknown | — | 914 | RenJi HospitalOTHER | 0 | Jul 22, 2024 | clinicaltrials |
| NCT05183243 | GH21 Capsules for Advanced Solid Tumors: A Study on Safety and Early Results | unknown | Phase 1 | 68 | Suzhou Genhouse Bio Co., Ltd.OTHER | 1 | Jul 16, 2024 | clinicaltrials |
| NCT06502704 | Bile Acids and Microbiome in Early Colorectal Carcinogenesis | unknown | — | 60 | Vilnius UniversityOTHER | 1 | Jul 16, 2024 | clinicaltrials |
| NCT06495853 | Prospective Phase II Study on Continuous Circumferential Reinforcement of Laparoscopic Rectal Anastomosis to Prevent Complications | unknown | Phase 2 | 208 | ZHI-ZHONG PANOTHER | 1 | Jul 11, 2024 | clinicaltrials |
| NCT01171300 | Assessment of Response Before, During and After Neoadjuvant Chemoradiotherapy in Rectal Cancer Patients | unknown | N/A | 94 | Universitaire Ziekenhuizen KU LeuvenOTHER | 1 | Jul 10, 2024 | clinicaltrials |
| NCT04715633 | PD-1 Inhibitors Combined With VEGF Inhibitors for Locally Advanced dMMR/MSI-H Colorectal Cancer | unknown | Phase 2 | 53 | Sun Yat-sen UniversityOTHER | 1 | Jul 9, 2024 | clinicaltrials |
| NCT06491355 | First-Line Treatment Induced With mFOLFOX6 and HLX04 Regimen, Following Combined With Serplulimab in MSS Initially Unresectable Metastatic Colorectal Cancer | unknown | Phase 2 | 72 | Sir Run Run Shaw HospitalOTHER | 1 | Jul 9, 2024 | clinicaltrials |
| NCT02355379 | Randomised Study Evaluating Adjuvant Chemotherapy After Resection of Stage III Colonic Adenocarcinoma in Patients of 70 and Over(ADAGE) | unknown | Phase 3 | 774 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Jul 8, 2024 | clinicaltrials |
| NCT05229003 | Irinotecan Plus Anlotinib or Further in Combination With Penpulimab for Second-line Treatment of mCRC | unknown | Phase 2 | 44 | Fudan UniversityOTHER | 1 | Jul 3, 2024 | clinicaltrials |
| NCT06485713 | Efficacy and Safety of Trifluridine/Tipiracil Combined With Fufuquitinib for Third-line Treatment of mCRC | unknown | Phase 2 | 200 | First Affiliated Hospital of Wenzhou Medical UniversityOTHER | 1 | Jul 3, 2024 | clinicaltrials |
| NCT06481605 | A Novel Adaptive Anastomotic Technique for Left-sided Colonic and Rectal Resection(NOVA) | unknown | N/A | 30 | Istituto Clinico HumanitasOTHER | 1 | Jul 1, 2024 | clinicaltrials |
| NCT04896684 | Chronic Intestinal Pathologies Analytical Cohort at TouLouse(CAPITOL) | unknown | — | 300 | University Hospital, ToulouseOTHER | 1 | Jun 28, 2024 | clinicaltrials |
Data updated 22 days agoSource updated Apr 4, 2025source: clinicaltrials