Clinical trial · Observational
A Prospective, Multi-center, Real-world Study of Ovarian Metastatic Colorectal Cancer Patients
Impact of Different Treatment Strategies on the Prognosis of Ovarian Metastatic Colorectal Cancer Patients: a Prospective, Multi-center, Real-world Study
NCT04716257CI-TRIAL-00079524proOMCRCunknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This prospective, multi-center, real-world study is conducted to investigate the impact of different treatment strategies (systemic chemotherapy combined with oophorectomy or with other local treatment or chemotherapy alone) on the prognosis of ovarian metastatic colorectal cancer patients.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Ovarian Metastasis | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Ovarian specific overall survival
- timeFrame
- up to 3 years
- description
- Calculated from the date of diagnosis with ovarian metastasis to death (caused by cancer) or last follow-up time.
Secondary outcomes (4)
- measure
- Ovarian specific objective response rate
- timeFrame
- 6 months
- description
- Response rate of ovarian metastases to systemic chemotherapy
- measure
- Extra-ovarian specific objective response rate
- timeFrame
- 6 months
- description
- Response rate of extra-ovarian metastases to systemic chemotherapy
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Histologically confirmed colorectal adenocarcinoma; 2. Histologically or radiologically diagnosed with ovarian metastasis, whether or not combined with metastases in other organs; 3. Women ≥18 years of age; 4. Eastern Cooperative Oncology Group performance status score ≤2; 5. Available imaging data if the disease is measurable according to RECIST criteria version 1.1; patients are eligible if there is no measurable lesion. 6. Complete medical records; 7. Informed consent form signed. Exclusion Criteria: 1. Not ovarian metastatic colorectal cancer confirmed by radiology or histology; 2. Drug abuse or other medical, psychological and social disorders that would interfere with cooperation with the requirements of the study; 3. Other conditions that would influence patient compliance; 4. Pregnant or breastfeeding female; male and female unwilling to take any contraceptive measures.
References
Publications (0)
Data not yet available
No reference posted for this study.