Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05257135 | A Clinico-biological Database in Cachexia in Patients With Colon Cancer(BCBCachexie) | recruiting | N/A | 150 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Feb 13, 2025 | clinicaltrials |
| NCT06809660 | Effects of Endocrine Disruptors on the Gut Microbiota and Assessment of Their Impact on Colorectal Cancer Development (PERMICA)(PERMICA) | recruiting | N/A | 200 | Poitiers University HospitalOTHER |
| 1 |
| Feb 13, 2025 |
| clinicaltrials |
| NCT06825624 | ARTEMIS-102: HS-20093 Combinations in Patients with Advanced Metastatic Colorectal Cancer | recruiting | Phase 1 | 560 | Hansoh BioMedical R&D CompanyINDUSTRY | 1 | Feb 13, 2025 | clinicaltrials |
| NCT04103567 | Determination of Microbiological Factors Associated With Poor Response to Neoadjuvant Treatment in Rectal Cancers(MICARE) | recruiting | N/A | 220 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Feb 12, 2025 | clinicaltrials |
| NCT06640166 | Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab.(ECLYPse) | recruiting | Phase 2 | 25 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Feb 12, 2025 | clinicaltrials |
| NCT06822634 | Advances in Imaging to Assess Response in Rectal Cancer(AIR-REC) | recruiting | — | 20 | NHS Greater Glasgow and ClydeOTHER | 1 | Feb 12, 2025 | clinicaltrials |
| NCT06819215 | Phase I/II Clinical Study to Evaluate VB15010 Tablets in Patients With Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 188 | Zhejiang Yangli Pharmaceutical Technology Co., Ltd.INDUSTRY | 1 | Feb 11, 2025 | clinicaltrials |
| NCT06276686 | Exercise for Improving Long-course Chemoradiotherapy Efficacy in People With Locally Advanced Rectal Cancer | recruiting | Early Phase 1 | 30 | University of HullOTHER | 1 | Feb 4, 2025 | clinicaltrials |
| NCT06805045 | Image-Guided Surgery In The Treatment Of Rectal Cancer (AR_CRC) | recruiting | N/A | 50 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 1 | Feb 3, 2025 | clinicaltrials |
| NCT03740503 | Genomic Investigation of Unusual Responders(GENIUS) | recruiting | — | 100 | University Health Network, TorontoOTHER | 1 | Jan 31, 2025 | clinicaltrials |
| NCT06802666 | Short-course Radiotherapy Followed by AK112 and CAPOX as Neoadjuvant Therapy for Locally Advanced Rectal Cancer | recruiting | Phase 2 | 45 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Jan 31, 2025 | clinicaltrials |
| NCT06793137 | Intestinal Microbiome Modulation With Antibiotics in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer | recruiting | Phase 2 | 100 | AC Camargo Cancer CenterOTHER | 1 | Jan 29, 2025 | clinicaltrials |
| NCT06799793 | Artificial Intelligence-based Screening Models for Prevention and Early Detection of Colorectal Cancer | recruiting | N/A | 1,400 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 1 | Jan 29, 2025 | clinicaltrials |
| NCT06522919 | Sequential Immunochemotherapy Treatment with Pembrolizumab Plus Dendritic Cell (DC) Vaccine Followed by Trifluridine/Tipiracil Plus Bevacizumab in Refractory Mismatch-repair-proficient (pMMR) or Microsatellite-stable (MSS) Metastatic Colorectal Cancer(CombiCoR-Vax) | recruiting | Phase 2 | 36 | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCSOTHER | 1 | Jan 28, 2025 | clinicaltrials |
| NCT06643793 | Evaluation of Irinotecan Liposome (II) Combined With 5-FU, LV, and Bevacizumab for mCRC | recruiting | Phase 2 | 30 | Affiliated Hospital of Nantong UniversityOTHER | 1 | Jan 28, 2025 | clinicaltrials |
| NCT06792604 | Host Genome Methylation: a Screening Tool in Anal Cancer Detection(AMethysT) | recruiting | N/A | 770 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Jan 24, 2025 | clinicaltrials |
| NCT06769828 | Ga-68-FAPI-46 PET for CRC Recurrence Detection in Elevated CEA(Ga-68-FAPI-46) | recruiting | N/A | 30 | Koo Foundation Sun Yat-Sen Cancer CenterOTHER | 1 | Jan 22, 2025 | clinicaltrials |
| NCT06787625 | Development of Organoids From Primary Colorectal Tumors and Synchronous Liver Metastases | recruiting | — | 10 | Regina Elena Cancer InstituteOTHER | 1 | Jan 22, 2025 | clinicaltrials |
| NCT02966483 | Transanal Versus Laparoscopic Total Mesorectal Excision for Rectal Cancer | recruiting | N/A | 1,114 | Sun Yat-sen UniversityOTHER | 1 | Jan 17, 2025 | clinicaltrials |
| NCT05793554 | CLASSICA: Validating AI in Classifying Cancer in Real-Time Surgery | recruiting | — | 600 | Mater Misericordiae University HospitalOTHER | 1 | Jan 17, 2025 | clinicaltrials |
| NCT06485609 | Clinical Study of Radical Right Hemicolectomy Versus Radical Right Hemicolectomy Combined with Indocyanine Green Fluorescence Imaging Lymphatic Tracer Dissection for the Treatment of Right Colon Cancer | recruiting | N/A | 1,200 | Sun Yat-sen UniversityOTHER | 1 | Jan 17, 2025 | clinicaltrials |
| NCT06776757 | Sintilimab in Combination with Cetuximab and Chemotherapy As First-line Treatment for RAS/BRAF Wild-type Advanced Colorectal Cancer | recruiting | Phase 1 / Phase 2 | 30 | Cancer Hospital Chinese Academy of Medical Science, Shenzhen CenterOTHER | 1 | Jan 15, 2025 | clinicaltrials |
| NCT06765252 | Effect of Genetic Polymorphism on Capecitabine-Induced Toxicity in Egyptian Cancer Patients | recruiting | — | 80 | Ain Shams UniversityOTHER | 1 | Jan 9, 2025 | clinicaltrials |
| NCT06765616 | Adebrelimab Injection (PD-L1) Combined With Short Course Radiotherapy and Chemotherapy for Neoadjuvant Therapy of Locally Advanced Rectal Cancer | recruiting | Phase 2 | 31 | Feng TianOTHER_GOV | 1 | Jan 9, 2025 | clinicaltrials |
| NCT03941080 | Gut Microbiome Dynamics in Metastasized or Irresectable Colorectal Cancer(GIMICC) | recruiting | — | 300 | University Medical Center GroningenOTHER | 1 | Jan 1, 2025 | clinicaltrials |
| NCT05709249 | Xian-Lian-Jie-Du Optimization Decoction As an Adjuvant Treatment for Prevention of Recurrence of Colon Cancer | recruiting | Phase 3 | 730 | Jiangsu Famous Medical Technology Co., Ltd.INDUSTRY | 1 | Dec 30, 2024 | clinicaltrials |
| NCT06287671 | Colorectal Omics and OfCS Proteoglycans(COCO) | recruiting | — | 1,000 | Claus Anders Bertelsen, PhD, MDOTHER | 1 | Dec 30, 2024 | clinicaltrials |
| NCT06751914 | Neoantigen-based Peptide Vaccine and Conventional Second-line Therapy for CRC Progressed After First-line Treatment | recruiting | N/A | 10 | The First Affiliated Hospital of Nanchang UniversityOTHER | 1 | Dec 30, 2024 | clinicaltrials |
| NCT06751940 | Neoantigen-loaded DC Vaccine and Conventional Second-line Therapy for CRC Progressed After First-line Treatment | recruiting | N/A | 10 | The First Affiliated Hospital of Nanchang UniversityOTHER | 1 | Dec 30, 2024 | clinicaltrials |
| NCT06751953 | Neoantigen-loaded DC Vaccine and Conventional Third-line Therapy for CRC Progressed After Second-line Treatment | recruiting | N/A | 10 | The First Affiliated Hospital of Nanchang UniversityOTHER | 1 | Dec 30, 2024 | clinicaltrials |
| NCT06751966 | Neoantigen-based Peptide Vaccine and Conventional Third-line Therapy for CRC Progressed After Second-line Treatment | recruiting | N/A | 10 | The First Affiliated Hospital of Nanchang UniversityOTHER | 1 | Dec 30, 2024 | clinicaltrials |
| NCT05501379 | Comparison of the Physical Activity in Cancer Patients Assessed by Questionnaire and Motion Tracker(OncoPhys) | recruiting | — | 60 | University Medicine GreifswaldOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT05894694 | Survival Benefit of Compound Kushen Injection in the Treatment of Advanced Colorectal Cancer | recruiting | Phase 4 | 320 | Guang'anmen Hospital of China Academy of Chinese Medical SciencesOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT06613165 | Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer | recruiting | — | 100 | Xijing HospitalOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT06749015 | A Study on Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC) | recruiting | — | 100 | Fudan UniversityOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT05601505 | Circulating Tumor DNA-guided Neoadjuvant Treatment Strategy for Locally Advanced Rectal Cancer(CINTS-R) | recruiting | Phase 2 | 470 | Peking Union Medical College HospitalOTHER | 1 | Dec 24, 2024 | clinicaltrials |
| NCT06425133 | Regorafenib in Combination With Multimodal Metronomic Chemotherapy for Chemo-resistant Metastatic Colorectal Cancers(CARE) | recruiting | Phase 2 | 174 | Centre Hospitalier Universitaire de BesanconOTHER | 1 | Dec 24, 2024 | clinicaltrials |
| NCT05462613 | Regorafenib With Low-dose Chemotherapies and Aspirin Followed by Standard Chemotherapies in Metastatic Colorectal Cancer(REPROGRAM-02) | recruiting | Phase 2 / Phase 3 | 446 | Centre Hospitalier Universitaire de BesanconOTHER | 1 | Dec 20, 2024 | clinicaltrials |
| NCT06281678 | A Study of IBI363 in Subjects with Advanced Solid Malignancies | recruiting | Phase 2 | 178 | Innovent Biologics (Suzhou) Co. Ltd.INDUSTRY | 1 | Dec 19, 2024 | clinicaltrials |
| NCT04687631 | Conversion Therapy of RAS/BRAF Wild-Type Colorectal Cancer Patients With Initially Unresectable Liver Metastases | recruiting | Phase 3 | 508 | Fudan UniversityOTHER | 1 | Dec 18, 2024 | clinicaltrials |
| NCT06542588 | Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy, HLX07and Serplulimab in LARC | recruiting | Phase 2 | 29 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Dec 18, 2024 | clinicaltrials |
| NCT04920149 | Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome(MesaCAPP) | recruiting | Phase 2 | 150 | Ann-Sofie BackmanOTHER | 2 | Dec 17, 2024 | clinicaltrials |
| NCT06710067 | Urine Metabolites in the Diagnosis of Disease | recruiting | — | 1,250 | Luventix, Inc.INDUSTRY | 1 | Dec 13, 2024 | clinicaltrials |
| NCT06242418 | CtDNA in Adjuvant Chemotherapy of Stage III Colon Cancer (REVISE Trial)(REVISE) | recruiting | Phase 2 | 60 | West China HospitalOTHER | 1 | Dec 12, 2024 | clinicaltrials |
| NCT02185443 | Stereotactic Body Radiation Therapy (SBRT) for Unresectable Liver Metastases | recruiting | Phase 2 | 43 | University of Sao PauloOTHER | 1 | Dec 9, 2024 | clinicaltrials |
| NCT06236373 | The Unmet Needs of Cancer Survivors in Ausl IRCCS Reggio Emilia(Survivorship) | recruiting | — | 45 | University of Modena and Reggio EmiliaOTHER | 1 | Dec 9, 2024 | clinicaltrials |
| NCT06718738 | Clinical Study of IM96 CAR-T Cell Therapy in Patients With Advanced Colorectal Cancer | recruiting | Phase 1 | 9 | Beijing Immunochina Medical Science & Technology Co., Ltd.INDUSTRY | 1 | Dec 5, 2024 | clinicaltrials |
| NCT05916040 | Total Neoadjuvant Treatment of Rectal Cancer by MRI-guided Radiotherapy(TNTRect) | recruiting | — | 35 | Universitair Ziekenhuis BrusselOTHER | 1 | Dec 4, 2024 | clinicaltrials |
| NCT05933122 | Study of the Prevalence of Sexual Dysfunction in Women After Rectal Cancer Surgery and Analysis of the Impact of a Sexologist Intervention(RectSexQol) | recruiting | N/A | 144 | University Hospital, LimogesOTHER | 1 | Dec 2, 2024 | clinicaltrials |
Data updated 23 days agoSource updated Feb 13, 2025source: clinicaltrials