Clinical trial · Observational
Post-contracture Release Radiation for Dupuytren's Disease
Efficacy of Post-contracture Release Radiation for the Treatment of Dupuytren's Disease
NCT04122313CI-TRIAL-00106005recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To determine if the clinical impression of clinicians, ie that patients are improving with the current treatment pathway for Dupuytren's (contracture release followed by radiation), can be substantiated with scientific evidence.
Conditions
Conditions (11)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Dupuytren Contracture | Palmar Fibromatosis | ALIAS | 0.90 |
| Dupuytren Contracture of Left Palm | — | UNRESOLVED | — |
| Dupuytren Contracture of Right Palm | — | UNRESOLVED | — |
| Dupuytren Disease of Finger | — | UNRESOLVED | — |
| Dupuytren Disease of Palm and Finger | — | UNRESOLVED | — |
| Dupuytren's Contracture Left | — | UNRESOLVED | — |
| Dupuytrens Contracture of Both Hands | — | UNRESOLVED | — |
| Dupuytren's Contracture Right | — | UNRESOLVED | — |
| Dupuytren's Disease | — | UNRESOLVED | — |
| Dupuytren's Disease of Palm of Left Hand | — | UNRESOLVED |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Evaluation of Dupuytren's Disease Treatment | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients with Dupuytren's Contracture Disease
- description
- Patients with Dupuytren's Disease following the current treatment pathway
- interventionNames
- Other: Evaluation of Dupuytren's Disease Treatment
Primary outcomes (1)
- measure
- Southampton Dupuytren's Scoring System (SDSS) Questionnaire
- timeFrame
- 2 years
- description
- The primary study endpoint is the patient's self-reported function which will be assessed using the validated Southampton Dupuytren's Scoring System (SDSS) questionnaire. The SDSS is a 5 item questionnaire with item scores ranging from 0 (no problem) to 4 (severe problem). Total scores are a sum of the 5 item scores with a total score range of 0 to 20. High scores indicate greater impairment due to the disease.
Secondary outcomes (1)
- measure
- Common Terminology Criteria for Adverse Events (CTCAE)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnoses of Dupuytren's disease * English-speaking Exclusion Criteria: \- Patients with Dupuytren's disease who are not currently seeking treatment
References
Publications (0)
Data not yet available
No reference posted for this study.