Subtype
Intermediate Soft Tissue Neoplasm
CI-CAN-00001021Explore in graph →
Non-malignant32 active trials42 evidence items
- NCIt
- C7653
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Subtype
CI-CAN-00001021Explore in graph →
Clinical trials
136 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03785964 | Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)(DeFi) | completed | Phase 3 | 142 | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, GermanyINDUSTRY | 7 | Aug 20, 2026 | clinicaltrials |
| NCT06248866 | Effect Of Extracorporeal Shock Wave Therapy On Ultrasonography Changes In Patients With Palmar Fibromatosis: A Randomized Controlled Trial(ESWT) | completed | N/A | 60 | Cairo University |
| 1 |
| Jul 14, 2026 |
| clinicaltrials |
| NCT06151197 | Study to Assess EN3835 in the Treatment of Plantar Fibromatosis (Also Known as Ledderhose Disease)(STRIDE) | completed | Phase 3 | 436 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 2 | Jul 13, 2026 | clinicaltrials |
| NCT02066181 | Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis | completed | Phase 3 | 87 | National Cancer Institute (NCI)NIH | 2 | Jun 24, 2026 | clinicaltrials |
| NCT02180867 | Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery | completed | Phase 2 / Phase 3 | 140 | National Cancer Institute (NCI)NIH | 3 | Jun 17, 2026 | clinicaltrials |
| NCT05152173 | Efficacy, Safety, and Tolerability, of EN3835 vs Placebo in the Treatment of Plantar Fibromatosis | completed | Phase 2 | 176 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 1 | Mar 27, 2026 | clinicaltrials |
| NCT02476305 | Evaluation of the Cryodestruction of Non Abdominopelvic Desmoid Tumors in Patients Progressing Despite Medical Treatment(CRYODESMO01) | completed | N/A | 50 | University Hospital, Strasbourg, FranceOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT02547831 | Tailored Beta-catenin Mutational Approach in Extra-abdominal Sporadic Desmoids Tumor Patients | completed | — | 100 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Sep 11, 2025 | clinicaltrials |
| NCT06258421 | Burden of Disease and Living Situation in Desmoid Patients(PROSa Desmoid) | completed | — | 100 | Technische Universität DresdenOTHER | 1 | Aug 24, 2025 | clinicaltrials |
| NCT03407820 | Nylon Versus Chromic Gut Sutures for Minor Hand Surgery | completed | N/A | 112 | University of Texas at AustinOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT02228889 | RCT of Two Noncrosslinked Porcine Acellular Dermal Matrices in Ab Wall Reconstruction | completed | N/A | 46 | Jeffrey JanisOTHER | 1 | Jun 6, 2025 | clinicaltrials |
| NCT05254457 | Long-Term Safety, Efficacy, and Durability of EN3835 in the Treatment and Retreatment of Plantar Fibromatosis | completed | Phase 3 | 145 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 1 | Mar 21, 2025 | clinicaltrials |
| NCT04874870 | Effectiveness of Splinting After Collagenase Injection | completed | Phase 3 | 80 | Foundation for Orthopaedic Research and EducationOTHER | 1 | Feb 26, 2025 | clinicaltrials |
| NCT03190174 | Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers | completed | Phase 1 / Phase 2 | 34 | Sarcoma Oncology Research Center, LLCOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT02076906 | MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors | completed | Phase 1 | 7 | AeRang KimOTHER | 1 | Jan 1, 2025 | clinicaltrials |
| NCT03802084 | A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor | completed | Phase 1 / Phase 2 | 24 | Hyo Song KimOTHER | 1 | May 13, 2024 | clinicaltrials |
| NCT04229147 | Ledderhose Disease - Long Term Effects of Radiotherapy Treatment. LedRad LTE - Study | completed | — | 68 | University Medical Center GroningenOTHER | 1 | Feb 28, 2024 | clinicaltrials |
| NCT01981551 | Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis | completed | Phase 2 | 17 | National Cancer Institute (NCI)NIH | 1 | Feb 6, 2024 | clinicaltrials |
| NCT06195085 | CT-guided Radioactive Iodine-125 Seed Implantation for Recurrent Desmoid Tumors | completed | — | 38 | Peking University Third HospitalOTHER | 1 | Jan 8, 2024 | clinicaltrials |
| NCT01923103 | Natural Disease Progress of Dupuytren Disease(DD) | completed | — | 261 | University Medical Center GroningenOTHER | 1 | Dec 5, 2023 | clinicaltrials |
| NCT00928525 | Imatinib in Patients With Desmoid Tumor and Chondrosarcoma(Basket 1) | completed | Phase 2 | 35 | Italian Sarcoma GroupNETWORK | 1 | Oct 5, 2023 | clinicaltrials |
| NCT00919269 | Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma | completed | — | 150 | Children's Oncology GroupNETWORK | 7 | Oct 3, 2023 | clinicaltrials |
| NCT04448873 | Guided Discontinuation Versus Maintenance Treatment of Sirolimus in Pediatric Patients With Kaposiform Hemangioendothelioma | completed | Phase 4 | 30 | Children's Hospital of Fudan UniversityOTHER | 1 | Sep 26, 2023 | clinicaltrials |
| NCT04289077 | Quality of Life of Patients With Desmoid-type Fibromatosis(QUALIFIED) | completed | — | 156 | Erasmus Medical CenterOTHER | 2 | Sep 7, 2023 | clinicaltrials |
| NCT01265030 | A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis | completed | Phase 1 / Phase 2 | 9 | MaineHealthOTHER | 1 | Jun 26, 2023 | clinicaltrials |
| NCT03459469 | Phase I, Open-label, Non-randomized Study to Evaluate Safety of BC2059 | completed | Phase 1 | 24 | Iterion TherapeuticsINDUSTRY | 2 | Mar 1, 2023 | clinicaltrials |
| NCT04077515 | Safety and Efficacy of Low-dose Sirolimus to Kaposiform Hemangioendothelioma | completed | Phase 4 | 92 | Children's Hospital of Fudan UniversityOTHER | 1 | Jan 30, 2023 | clinicaltrials |
| NCT00346164 | Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma | completed | Phase 3 | 588 | Children's Oncology GroupNETWORK | 5 | Apr 28, 2022 | clinicaltrials |
| NCT02647619 | Dupuytren´s Disease Study. Primary Disease, MCP Joint, Xiapex, PNF | completed | Phase 4 | 80 | University Hospital, AkershusOTHER | 1 | Apr 26, 2022 | clinicaltrials |
| NCT03188068 | Sirolimus Versus Sirolimus Plus Prednisolone for Kaposiform Hemangioendothelioma | completed | Phase 2 | 30 | West China HospitalOTHER | 1 | Apr 21, 2022 | clinicaltrials |
| NCT03966742 | Doxorubicin Eluting Intra-arterial Embolization for Aggressive Desmoid Fibromatosis | completed | Phase 2 | 8 | Rabin Medical CenterOTHER | 1 | Mar 25, 2022 | clinicaltrials |
| NCT02983162 | Is wGRS Associated With DD Recurrence? | completed | — | 427 | University Medical Center GroningenOTHER | 1 | Feb 10, 2022 | clinicaltrials |
| NCT03381846 | Treatment of Dermatofibrosarcoma Protuberans in Patients 10 Years and Younger | completed | N/A | 7 | Mayo ClinicOTHER | 1 | Aug 5, 2020 | clinicaltrials |
| NCT02310503 | Spanish Registry of Mohs Surgery(REGESMOHS) | completed | — | 6,000 | Fundación Academia Española de DermatologíaOTHER | 1 | May 5, 2020 | clinicaltrials |
| NCT03331926 | Collagenase is a Common Treatment of MCP and PIP Joint Contractures in Dupuytrens Disease | completed | — | 199 | Jeppe LangeOTHER | 0 | Apr 22, 2020 | clinicaltrials |
| NCT00068419 | Sulindac and Tamoxifen in Treating Patients With Desmoid Tumor | completed | Phase 2 | 70 | Children's Oncology GroupNETWORK | 1 | Feb 19, 2020 | clinicaltrials |
| NCT01962103 | Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors | completed | Phase 1 / Phase 2 | 107 | CelgeneINDUSTRY | 7 | Dec 27, 2019 | clinicaltrials |
| NCT03868449 | Question Prompt List for Common Hand Conditions | completed | N/A | 126 | Stanford UniversityOTHER | 1 | Oct 16, 2019 | clinicaltrials |
| NCT03111186 | Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery | completed | Phase 2 | 40 | University of Southern CaliforniaOTHER | 1 | Sep 26, 2019 | clinicaltrials |
| NCT01154452 | Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma | completed | Phase 1 / Phase 2 | 78 | National Cancer Institute (NCI)NIH | 1 | Aug 15, 2018 | clinicaltrials |
| NCT00659360 | AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma | completed | Phase 2 | 17 | National Cancer Institute (NCI)NIH | 2 | Jun 29, 2018 | clinicaltrials |
| NCT03573765 | Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data | completed | — | 8,308,821 | University of OxfordOTHER | 0 | Jun 29, 2018 | clinicaltrials |
| NCT00528606 | AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Dupuytren's Contracture(CORD-I) | completed | Phase 3 | 308 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 1 | Dec 2, 2017 | clinicaltrials |
| NCT01444729 | Post Approval Commitment Study | completed | — | 305 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 2 | Oct 26, 2017 | clinicaltrials |
| NCT00528931 | A Pharmacokinetic Study of AA4500 (XIAFLEX™, Proposed Name) in Subjects With Dupuytren's Contracture | completed | Phase 1 | 16 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 1 | Oct 5, 2017 | clinicaltrials |
| NCT01407068 | Administration of Two Injections for Multiple Dupuytren's Contractures | completed | Phase 3 | 60 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 2 | Oct 5, 2017 | clinicaltrials |
| NCT01674634 | Safety and Efficacy of Two Concurrent Injections of AA4500 in Adult Subjects With Multiple Dupuytren's Contractures | completed | Phase 3 | 715 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 1 | Oct 5, 2017 | clinicaltrials |
| NCT01137916 | Study to Evaluate Imatinib in Desmoid Tumors | completed | Phase 2 | 39 | Heidelberg UniversityOTHER | 1 | May 3, 2017 | clinicaltrials |
| NCT01588353 | Collagenase Option for Reduction of Dupuytren's Contracture in Japan(CORD-J) | completed | Phase 3 | 104 | Asahi Kasei Therapeutics CorporationINDUSTRY | 1 | Mar 21, 2017 | clinicaltrials |
| NCT00171912 | Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes | completed | Phase 2 | 38 | Novartis PharmaceuticalsINDUSTRY | 1 | Feb 23, 2017 | clinicaltrials |
Data updated 22 days agoSource updated Aug 20, 2026source: clinicaltrials