Cancer Family
Fibroblastic Neoplasm
CI-CAN-00000181Explore in graph →
Non-malignant45 active trials52 evidence items
- NCIt
- C7075
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Cancer Family
CI-CAN-00000181Explore in graph →
Clinical trials
203 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07755176 | Patient-reported Outcomes Following Percutaneous Ablation of Desmoid Tumors | enrolling by invitation | — | 30 | Mayo ClinicOTHER | 1 | Sep 29, 2026 | clinicaltrials |
| NCT07158892 | Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test | not yet recruiting | N/A | 220 | University of Texas at AustinOTHER | 1 | Sep 22, 2026 | clinicaltrials |
| NCT07170644 |
| A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF) |
| active not recruiting |
| Phase 2 |
| 20 |
| SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, GermanyINDUSTRY |
| 1 |
| Sep 15, 2026 |
| clinicaltrials |
| NCT07176689 | Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF) | recruiting | Phase 4 | 50 | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, GermanyINDUSTRY | 6 | Sep 14, 2026 | clinicaltrials |
| NCT05949099 | Study of Cryoablation and Nirogacestat for Desmoid Tumor | recruiting | Phase 2 | 28 | Nam BuiOTHER | 1 | Sep 10, 2026 | clinicaltrials |
| NCT05711615 | Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma | recruiting | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | Sep 4, 2026 | clinicaltrials |
| NCT02402244 | Project: Every Child for Younger Patients With Cancer | recruiting | — | 75,000 | Children's Oncology GroupNETWORK | 6 | Aug 25, 2026 | clinicaltrials |
| NCT04851119 | Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors | recruiting | Phase 1 / Phase 2 | 147 | Children's Oncology GroupNETWORK | 1 | Aug 25, 2026 | clinicaltrials |
| NCT03785964 | Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)(DeFi) | completed | Phase 3 | 142 | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, GermanyINDUSTRY | 7 | Aug 20, 2026 | clinicaltrials |
| NCT06239272 | NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) | recruiting | Phase 1 / Phase 2 | 139 | St. Jude Children's Research HospitalOTHER | 1 | Aug 3, 2026 | clinicaltrials |
| NCT04195399 | A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by Surgery | active not recruiting | Phase 2 | 31 | Children's Oncology GroupNETWORK | 5 | Jul 30, 2026 | clinicaltrials |
| NCT06330545 | Radiation Therapy for Dupuytren's Contracture Following Non-Surgical Release | recruiting | N/A | 95 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Jul 28, 2026 | clinicaltrials |
| NCT07010224 | Elastofibroma Dorsi: Clinical Features, Surgical Outcomes, and Risk Factors | completed | — | 102 | Ondokuz Mayıs UniversityOTHER | 0 | Jul 24, 2026 | clinicaltrials |
| NCT07227649 | NAC-REPAIR for Post-surgical Pain | not yet recruiting | Phase 2 | 80 | University of ArizonaOTHER | 1 | Jul 17, 2026 | clinicaltrials |
| NCT06248866 | Effect Of Extracorporeal Shock Wave Therapy On Ultrasonography Changes In Patients With Palmar Fibromatosis: A Randomized Controlled Trial(ESWT) | completed | N/A | 60 | Cairo UniversityOTHER | 1 | Jul 14, 2026 | clinicaltrials |
| NCT06151197 | Study to Assess EN3835 in the Treatment of Plantar Fibromatosis (Also Known as Ledderhose Disease)(STRIDE) | completed | Phase 3 | 436 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 2 | Jul 13, 2026 | clinicaltrials |
| NCT07118176 | Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers | active not recruiting | Phase 1 | 30 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Jul 2, 2026 | clinicaltrials |
| NCT02066181 | Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis | completed | Phase 3 | 87 | National Cancer Institute (NCI)NIH | 2 | Jun 24, 2026 | clinicaltrials |
| NCT07661342 | DEPART Study at Yale(Dupuytren's) | not yet recruiting | Phase 3 | 158 | Yale UniversityOTHER | 1 | Jun 22, 2026 | clinicaltrials |
| NCT02180867 | Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery | completed | Phase 2 / Phase 3 | 140 | National Cancer Institute (NCI)NIH | 3 | Jun 17, 2026 | clinicaltrials |
| NCT02834013 | Nivolumab and Ipilimumab in Treating Patients With Rare Tumors | active not recruiting | Phase 2 | 798 | National Cancer Institute (NCI)NIH | 2 | Jun 17, 2026 | clinicaltrials |
| NCT07646080 | Exploratory Study on Toripalimab and Anlotinib Combined With Standard Chemotherapy for Refractory Dermatofibrosarcoma Protuberans | not yet recruiting | Phase 2 | 20 | Yanjie Zhang, MDOTHER | 0 | Jun 16, 2026 | clinicaltrials |
| NCT07640425 | Safety and Efficacy Study of Collagenase CNT201 Injection for Treatment of Dupuytren's Contracture | recruiting | Phase 1 / Phase 2 | 60 | CONNEXTINDUSTRY | 1 | Jun 12, 2026 | clinicaltrials |
| NCT06789172 | A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors(INVOKE) | recruiting | Phase 1 | 146 | EpkinINDUSTRY | 3 | Jun 11, 2026 | clinicaltrials |
| NCT04871282 | A Study of AL102 in Patients With Progressing Desmoid Tumors(RINGSIDE) | active not recruiting | Phase 2 / Phase 3 | 198 | Immunome, Inc.INDUSTRY | 11 | Jun 8, 2026 | clinicaltrials |
| NCT04281381 | Observing People With Desmoid-Type Fibromatosis | recruiting | — | 100 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 15, 2026 | clinicaltrials |
| NCT06660121 | Electrochemotherapy for Desmoid Tumors(ECT-DESMO) | withdrawn | — | 0 | Istituto Ortopedico RizzoliOTHER | 1 | May 14, 2026 | clinicaltrials |
| NCT05041036 | Individual Patient Compassionate Use of Nirogacestat | available | — | — | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, GermanyINDUSTRY | 0 | May 8, 2026 | clinicaltrials |
| NCT07541430 | A Study in Adults With Desmoid Tumors | recruiting | Phase 2 | 50 | Elpiscience (Suzhou) Biopharma, Ltd.INDUSTRY | 1 | Apr 30, 2026 | clinicaltrials |
| NCT03192020 | Trial Comparing Treatment Strategies in Dupuytren's Contracture(DETECT) | active not recruiting | Phase 4 | 302 | Tampere UniversityOTHER | 1 | Apr 29, 2026 | clinicaltrials |
| NCT04332874 | A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg | recruiting | Phase 2 | 30 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Apr 23, 2026 | clinicaltrials |
| NCT06638931 | Agnostic Therapy in Rare Solid Tumors(ANTARES) | recruiting | Phase 2 | 28 | Instituto do Cancer do Estado de São PauloOTHER | 1 | Apr 15, 2026 | clinicaltrials |
| NCT02867033 | National Clinical-biological Prospective Cohort of Incident Cases of Aggressive Fibromatosis (ALTITUDES)(ALTITUDES) | active not recruiting | N/A | 628 | Centre Oscar LambretOTHER | 1 | Mar 30, 2026 | clinicaltrials |
| NCT05160922 | Crizotinib Continuation Clinical Study | active not recruiting | Phase 4 | 27 | PfizerINDUSTRY | 5 | Mar 30, 2026 | clinicaltrials |
| NCT05152173 | Efficacy, Safety, and Tolerability, of EN3835 vs Placebo in the Treatment of Plantar Fibromatosis | completed | Phase 2 | 176 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 1 | Mar 27, 2026 | clinicaltrials |
| NCT07496242 | Immunological Phenotype of Desmoid-fibromatosis-affected Patients. | recruiting | — | 200 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 2 | Mar 27, 2026 | clinicaltrials |
| NCT04122313 | Post-contracture Release Radiation for Dupuytren's Disease | recruiting | — | 50 | University of MinnesotaOTHER | 1 | Mar 19, 2026 | clinicaltrials |
| NCT03155854 | The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring | recruiting | N/A | 50 | Mayo ClinicOTHER | 1 | Mar 16, 2026 | clinicaltrials |
| NCT04420975 | Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma | active not recruiting | Phase 1 | 14 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT07461246 | Familial Adenomatous Poliposys Italian Network (Rete Italiana Poliposi Adenomatosa Familiare)(RIPAF) | active not recruiting | — | 1,500 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT04008238 | Prospective Identification of Predictive Biomarkers of Trabectedin Efficacy in Non-L Soft-tissue Sarcoma Patients(PIPER) | completed | N/A | 29 | Institut BergoniéOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT07443371 | Effect of Transfer Energy Capacitive and Resistive Therapy on Palmar Fibromatosis | not yet recruiting | N/A | 36 | Cairo UniversityOTHER | 1 | Mar 2, 2026 | clinicaltrials |
| NCT03967834 | Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group(MIRAS) | recruiting | N/A | 400 | Institut Claudius RegaudOTHER | 1 | Feb 10, 2026 | clinicaltrials |
| NCT06387485 | A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative Planning | recruiting | N/A | 150 | Ricoh USA, Inc.INDUSTRY | 1 | Feb 6, 2026 | clinicaltrials |
| NCT05111964 | HIFU Ablation of Soft Tissue Sarcoma(SarcAblate) | recruiting | N/A | 10 | Oxford University Hospitals NHS TrustOTHER | 1 | Feb 4, 2026 | clinicaltrials |
| NCT07169344 | Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma(PROSARC-1) | recruiting | Phase 2 | 110 | Oslo University HospitalOTHER | 1 | Jan 28, 2026 | clinicaltrials |
| NCT07173972 | Dose-escalated, Hypofractionated, Definitive Proton Radiotherapy for Patients With Inoperable Soft Tissue Sarcoma.(PROSARC-2) | recruiting | Phase 2 | 40 | Oslo University HospitalOTHER | 1 | Jan 28, 2026 | clinicaltrials |
| NCT02476305 | Evaluation of the Cryodestruction of Non Abdominopelvic Desmoid Tumors in Patients Progressing Despite Medical Treatment(CRYODESMO01) | completed | N/A | 50 | University Hospital, Strasbourg, FranceOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT06849986 | IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS)(TAIS) | recruiting | Phase 2 | 45 | Fudan UniversityOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT03899792 | A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors(LIBRETTO-121) | active not recruiting | Phase 1 / Phase 2 | 36 | Eli Lilly and CompanyINDUSTRY | 11 | Jan 6, 2026 | clinicaltrials |
Data updated 1 hour agoSource updated Sep 29, 2026source: clinicaltrials