Cancer Family
Fibroblastic Neoplasm
CI-CAN-00000181Explore in graph →
Non-malignant45 active trials52 evidence items
- NCIt
- C7075
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Cancer Family
CI-CAN-00000181Explore in graph →
Clinical trials
203 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03785964 | Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)(DeFi) | completed | Phase 3 | 142 | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, GermanyINDUSTRY | 7 | Aug 20, 2026 | clinicaltrials |
| NCT06151197 | Study to Assess EN3835 in the Treatment of Plantar Fibromatosis (Also Known as Ledderhose Disease)(STRIDE) | completed | Phase 3 | 436 | Endo USA Inc., a Keenova Therapeutics Company |
| 2 |
| Jul 13, 2026 |
| clinicaltrials |
| NCT02066181 | Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis | completed | Phase 3 | 87 | National Cancer Institute (NCI)NIH | 2 | Jun 24, 2026 | clinicaltrials |
| NCT07661342 | DEPART Study at Yale(Dupuytren's) | not yet recruiting | Phase 3 | 158 | Yale UniversityOTHER | 1 | Jun 22, 2026 | clinicaltrials |
| NCT02180867 | Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery | completed | Phase 2 / Phase 3 | 140 | National Cancer Institute (NCI)NIH | 3 | Jun 17, 2026 | clinicaltrials |
| NCT04871282 | A Study of AL102 in Patients With Progressing Desmoid Tumors(RINGSIDE) | active not recruiting | Phase 2 / Phase 3 | 198 | Immunome, Inc.INDUSTRY | 11 | Jun 8, 2026 | clinicaltrials |
| NCT05254457 | Long-Term Safety, Efficacy, and Durability of EN3835 in the Treatment and Retreatment of Plantar Fibromatosis | completed | Phase 3 | 145 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 1 | Mar 21, 2025 | clinicaltrials |
| NCT04874870 | Effectiveness of Splinting After Collagenase Injection | completed | Phase 3 | 80 | Foundation for Orthopaedic Research and EducationOTHER | 1 | Feb 26, 2025 | clinicaltrials |
| NCT06370871 | Brightline-3: A Study to Find Out Whether Brigimadlin in Combination With Ezabenlimab Helps People With Advanced Soft Tissue Sarcoma | withdrawn | Phase 3 | 0 | Boehringer IngelheimINDUSTRY | 0 | Jul 17, 2024 | clinicaltrials |
| NCT03507010 | Ledderhose Disease: Radiotherapy or Not?(LedRad) | active not recruiting | Phase 3 | 84 | University Medical Center GroningenOTHER | 1 | Feb 28, 2024 | clinicaltrials |
| NCT05561036 | A Randomized, Double-blind,Phase Ⅲ Study of Liposome Doxorubicin in Desmoid Tumor | unknown | Phase 3 | 72 | Sun Yat-sen UniversityOTHER | 1 | Sep 30, 2022 | clinicaltrials |
| NCT00346164 | Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma | completed | Phase 3 | 588 | Children's Oncology GroupNETWORK | 5 | Apr 28, 2022 | clinicaltrials |
| NCT03874273 | Study of Crizotinib in Children and Adolescents With Myofibroblastic Tumors | unknown | Phase 2 / Phase 3 | 25 | Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyOTHER | 1 | Mar 14, 2019 | clinicaltrials |
| NCT02634931 | Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex | completed | Phase 3 | 94 | NobelpharmaINDUSTRY | 1 | Feb 20, 2019 | clinicaltrials |
| NCT00528606 | AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Dupuytren's Contracture(CORD-I) | completed | Phase 3 | 308 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 1 | Dec 2, 2017 | clinicaltrials |
| NCT01407068 | Administration of Two Injections for Multiple Dupuytren's Contractures | completed | Phase 3 | 60 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 2 | Oct 5, 2017 | clinicaltrials |
| NCT01674634 | Safety and Efficacy of Two Concurrent Injections of AA4500 in Adult Subjects With Multiple Dupuytren's Contractures | completed | Phase 3 | 715 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 1 | Oct 5, 2017 | clinicaltrials |
| NCT01588353 | Collagenase Option for Reduction of Dupuytren's Contracture in Japan(CORD-J) | completed | Phase 3 | 104 | Asahi Kasei Therapeutics CorporationINDUSTRY | 1 | Mar 21, 2017 | clinicaltrials |
| NCT02635789 | Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC) | completed | Phase 3 | 62 | NobelpharmaINDUSTRY | 1 | Feb 2, 2017 | clinicaltrials |
| NCT00014742 | Phase III Randomized Study of Collagenase in Patients With Residual Stage Dupuytren's Disease | completed | Phase 3 | 72 | State University of New YorkOTHER | 0 | Mar 25, 2015 | clinicaltrials |
| NCT01776892 | Collagenase and Needle Aponeurotomy: Single Modality Versus Combination Treatment for Dupuytren's Disease | withdrawn | Phase 3 | 0 | University of AlbertaOTHER | 1 | Apr 8, 2014 | clinicaltrials |
| NCT01229436 | Treatment Of Dupuytren's Contracture With Collagenase Clostridium Histolyticum Injection (Xiapex)(POINT X) | completed | Phase 3 | 254 | PfizerINDUSTRY | 8 | Mar 17, 2014 | clinicaltrials |
| NCT00565019 | Effects of Steroid Injection With Percutaneous Needle Aponeurotomy in Dupuytren's Contracture | completed | Phase 3 | 51 | Sunnybrook Health Sciences CentreOTHER | 1 | Dec 13, 2013 | clinicaltrials |
| NCT00931567 | Evaluation of the Efficiency of Autologous Platelet Gel (Platelet Rich Fibrin) Obtained From Own Patients' Blood Versus Vaselitulle in Dupuytren's Disease Postoperative Wound Healing | completed | Phase 2 / Phase 3 | 80 | Centre Hospitalier Universitaire de NiceOTHER | 1 | Mar 20, 2012 | clinicaltrials |
Data updated 22 days agoSource updated Aug 20, 2026source: clinicaltrials