Cancer Family
Fibroblastic Neoplasm
CI-CAN-00000181Explore in graph →
Non-malignant45 active trials52 evidence items
- NCIt
- C7075
Loading cancer entity…
Loading cancer entity…
Cancer Family
CI-CAN-00000181Explore in graph →
Clinical trials
203 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03785964 | Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)(DeFi) | completed | Phase 3 | 142 | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, GermanyINDUSTRY | 7 | Aug 20, 2026 | clinicaltrials |
| NCT07010224 | Elastofibroma Dorsi: Clinical Features, Surgical Outcomes, and Risk Factors | completed | — | 102 | Ondokuz Mayıs UniversityOTHER | 0 |
| Jul 24, 2026 |
| clinicaltrials |
| NCT06248866 | Effect Of Extracorporeal Shock Wave Therapy On Ultrasonography Changes In Patients With Palmar Fibromatosis: A Randomized Controlled Trial(ESWT) | completed | N/A | 60 | Cairo UniversityOTHER | 1 | Jul 14, 2026 | clinicaltrials |
| NCT06151197 | Study to Assess EN3835 in the Treatment of Plantar Fibromatosis (Also Known as Ledderhose Disease)(STRIDE) | completed | Phase 3 | 436 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 2 | Jul 13, 2026 | clinicaltrials |
| NCT02066181 | Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis | completed | Phase 3 | 87 | National Cancer Institute (NCI)NIH | 2 | Jun 24, 2026 | clinicaltrials |
| NCT02180867 | Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery | completed | Phase 2 / Phase 3 | 140 | National Cancer Institute (NCI)NIH | 3 | Jun 17, 2026 | clinicaltrials |
| NCT05152173 | Efficacy, Safety, and Tolerability, of EN3835 vs Placebo in the Treatment of Plantar Fibromatosis | completed | Phase 2 | 176 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 1 | Mar 27, 2026 | clinicaltrials |
| NCT04008238 | Prospective Identification of Predictive Biomarkers of Trabectedin Efficacy in Non-L Soft-tissue Sarcoma Patients(PIPER) | completed | N/A | 29 | Institut BergoniéOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT02476305 | Evaluation of the Cryodestruction of Non Abdominopelvic Desmoid Tumors in Patients Progressing Despite Medical Treatment(CRYODESMO01) | completed | N/A | 50 | University Hospital, Strasbourg, FranceOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT03425279 | CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma | completed | Phase 1 / Phase 2 | 245 | BioAtla, Inc.INDUSTRY | 3 | Sep 23, 2025 | clinicaltrials |
| NCT02547831 | Tailored Beta-catenin Mutational Approach in Extra-abdominal Sporadic Desmoids Tumor Patients | completed | — | 100 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Sep 11, 2025 | clinicaltrials |
| NCT04242238 | Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas | completed | Phase 1 | 32 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Aug 28, 2025 | clinicaltrials |
| NCT06258421 | Burden of Disease and Living Situation in Desmoid Patients(PROSa Desmoid) | completed | — | 100 | Technische Universität DresdenOTHER | 1 | Aug 24, 2025 | clinicaltrials |
| NCT03407820 | Nylon Versus Chromic Gut Sutures for Minor Hand Surgery | completed | N/A | 112 | University of Texas at AustinOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT02228889 | RCT of Two Noncrosslinked Porcine Acellular Dermal Matrices in Ab Wall Reconstruction | completed | N/A | 46 | Jeffrey JanisOTHER | 1 | Jun 6, 2025 | clinicaltrials |
| NCT05254457 | Long-Term Safety, Efficacy, and Durability of EN3835 in the Treatment and Retreatment of Plantar Fibromatosis | completed | Phase 3 | 145 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 1 | Mar 21, 2025 | clinicaltrials |
| NCT04874870 | Effectiveness of Splinting After Collagenase Injection | completed | Phase 3 | 80 | Foundation for Orthopaedic Research and EducationOTHER | 1 | Feb 26, 2025 | clinicaltrials |
| NCT03190174 | Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers | completed | Phase 1 / Phase 2 | 34 | Sarcoma Oncology Research Center, LLCOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT02076906 | MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors | completed | Phase 1 | 7 | AeRang KimOTHER | 1 | Jan 1, 2025 | clinicaltrials |
| NCT03023124 | Study With Trabectedin Versus Adriamycin Plus Dacarbazine, in Patients With Advanced Solitary Fibrous Tumor(STRADA) | completed | Phase 2 | 23 | Italian Sarcoma GroupNETWORK | 1 | Dec 9, 2024 | clinicaltrials |
| NCT06662734 | Infantile Versus Adult-type Fibrosarcoma and the Risk of Multiple Primary Malignancies | completed | — | 12,783 | asmaa salama ibrahimOTHER | 1 | Oct 29, 2024 | clinicaltrials |
| NCT03840772 | Eribulin in Advanced Solitary Fibrous Tumor(ERASING) | completed | Phase 2 | 16 | Italian Sarcoma GroupNETWORK | 1 | Sep 20, 2024 | clinicaltrials |
| NCT03802084 | A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor | completed | Phase 1 / Phase 2 | 24 | Hyo Song KimOTHER | 1 | May 13, 2024 | clinicaltrials |
| NCT04229147 | Ledderhose Disease - Long Term Effects of Radiotherapy Treatment. LedRad LTE - Study | completed | — | 68 | University Medical Center GroningenOTHER | 1 | Feb 28, 2024 | clinicaltrials |
| NCT01981551 | Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis | completed | Phase 2 | 17 | National Cancer Institute (NCI)NIH | 1 | Feb 6, 2024 | clinicaltrials |
| NCT06195085 | CT-guided Radioactive Iodine-125 Seed Implantation for Recurrent Desmoid Tumors | completed | — | 38 | Peking University Third HospitalOTHER | 1 | Jan 8, 2024 | clinicaltrials |
| NCT01923103 | Natural Disease Progress of Dupuytren Disease(DD) | completed | — | 261 | University Medical Center GroningenOTHER | 1 | Dec 5, 2023 | clinicaltrials |
| NCT02584309 | Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma | completed | Phase 2 | 73 | Washington University School of MedicineOTHER | 1 | Nov 7, 2023 | clinicaltrials |
| NCT00928525 | Imatinib in Patients With Desmoid Tumor and Chondrosarcoma(Basket 1) | completed | Phase 2 | 35 | Italian Sarcoma GroupNETWORK | 1 | Oct 5, 2023 | clinicaltrials |
| NCT00919269 | Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma | completed | — | 150 | Children's Oncology GroupNETWORK | 7 | Oct 3, 2023 | clinicaltrials |
| NCT04289077 | Quality of Life of Patients With Desmoid-type Fibromatosis(QUALIFIED) | completed | — | 156 | Erasmus Medical CenterOTHER | 2 | Sep 7, 2023 | clinicaltrials |
| NCT03009201 | Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery | completed | Phase 1 | 16 | OHSU Knight Cancer InstituteOTHER | 1 | Aug 16, 2023 | clinicaltrials |
| NCT01265030 | A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis | completed | Phase 1 / Phase 2 | 9 | MaineHealthOTHER | 1 | Jun 26, 2023 | clinicaltrials |
| NCT02066285 | Trial of Pazopanib in Patients With Solitary Fibrous Tumor and Extraskeletal Myxoid Chondrosarcoma | completed | Phase 2 | 96 | Grupo Espanol de Investigacion en SarcomasOTHER | 1 | Mar 27, 2023 | clinicaltrials |
| NCT03459469 | Phase I, Open-label, Non-randomized Study to Evaluate Safety of BC2059 | completed | Phase 1 | 24 | Iterion TherapeuticsINDUSTRY | 2 | Mar 1, 2023 | clinicaltrials |
| NCT03627741 | A Pilot Study of Intralesional Injection of Triamcinolone Acetonide for Desmoid Tumors | completed | Phase 1 | 10 | Mayo ClinicOTHER | 1 | Aug 25, 2022 | clinicaltrials |
| NCT00346164 | Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma | completed | Phase 3 | 588 | Children's Oncology GroupNETWORK | 5 | Apr 28, 2022 | clinicaltrials |
| NCT02647619 | Dupuytren´s Disease Study. Primary Disease, MCP Joint, Xiapex, PNF | completed | Phase 4 | 80 | University Hospital, AkershusOTHER | 1 | Apr 26, 2022 | clinicaltrials |
| NCT03966742 | Doxorubicin Eluting Intra-arterial Embolization for Aggressive Desmoid Fibromatosis | completed | Phase 2 | 8 | Rabin Medical CenterOTHER | 1 | Mar 25, 2022 | clinicaltrials |
| NCT02983162 | Is wGRS Associated With DD Recurrence? | completed | — | 427 | University Medical Center GroningenOTHER | 1 | Feb 10, 2022 | clinicaltrials |
| NCT02261207 | Phase II Study on Axitinib in Advanced Solitary Fibrous Tumor | completed | Phase 2 | 17 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Sep 28, 2021 | clinicaltrials |
| NCT01532687 | Gemcitabine With or Without Pazopanib in Treating Patients With Refractory Soft Tissue Sarcoma | completed | Phase 2 | 54 | OHSU Knight Cancer InstituteOTHER | 1 | Sep 27, 2021 | clinicaltrials |
| NCT01125046 | Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas | completed | Phase 2 | 50 | Northwestern UniversityOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT01024907 | Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas | completed | Phase 1 / Phase 2 | 23 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Dec 10, 2020 | clinicaltrials |
| NCT01526356 | Topical Rapamycin to Erase Angiofibromas in TSC(Treatment) | completed | Phase 2 | 179 | The University of Texas Health Science Center, HoustonOTHER | 2 | Oct 26, 2020 | clinicaltrials |
| NCT03381846 | Treatment of Dermatofibrosarcoma Protuberans in Patients 10 Years and Younger | completed | N/A | 7 | Mayo ClinicOTHER | 1 | Aug 5, 2020 | clinicaltrials |
| NCT02310503 | Spanish Registry of Mohs Surgery(REGESMOHS) | completed | — | 6,000 | Fundación Academia Española de DermatologíaOTHER | 1 | May 5, 2020 | clinicaltrials |
| NCT03331926 | Collagenase is a Common Treatment of MCP and PIP Joint Contractures in Dupuytrens Disease | completed | — | 199 | Jeppe LangeOTHER | 0 | Apr 22, 2020 | clinicaltrials |
| NCT00068419 | Sulindac and Tamoxifen in Treating Patients With Desmoid Tumor | completed | Phase 2 | 70 | Children's Oncology GroupNETWORK | 1 | Feb 19, 2020 | clinicaltrials |
Data updated 22 days agoSource updated Aug 20, 2026source: clinicaltrials