Subtype
Esophageal Squamous Cell Carcinoma
CI-CAN-00002629ESCCExplore in graph →
212 active trials3 approved drugs7 evidence items
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Subtype
CI-CAN-00002629ESCCExplore in graph →
Clinical trials
555 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (35)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03474341 | Preoperative Image-guided Identification of Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer(PRIDE) | unknown | — | 200 | UMC UtrechtOTHER | 1 | Nov 16, 2020 | clinicaltrials |
| NCT04602013 | Sintilimab Injection Combined With Concurrent CCRT in Locally Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 53 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Oct 26, 2020 |
| clinicaltrials |
| NCT04481100 | CCRT With Itraconazole in Locally Advanced Squamous Esophageal Cancer | unknown | Phase 2 | 38 | Hangzhou Cancer HospitalOTHER | 1 | Oct 14, 2020 | clinicaltrials |
| NCT04503967 | Efficacy and Safety of Anlotinib Hydrochloride Combined With Nivolumab in the Treatment of Gastric and Esophageal Cancer(OASIS) | unknown | Phase 2 | 48 | Shanghai Zhongshan HospitalOTHER | 0 | Aug 7, 2020 | clinicaltrials |
| NCT04437212 | Neoadjuvant Chemoradiotherapy Combined With Perioperative Toripalimab in Locally Advanced Esophageal Cancer | unknown | Phase 2 | 20 | RenJi HospitalOTHER | 1 | Jun 26, 2020 | clinicaltrials |
| NCT04440332 | Surveillance of Peripheral Blood of Lymphocyte and Immunocyte in Neoadjuvant Therapy Patients With Esophageal Squamous Cell Carcinoma (pLINE) | unknown | — | 138 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Jun 19, 2020 | clinicaltrials |
| NCT04229524 | Quantitative Assessment of Blood Supply in the Gastic Conduit With Fluorescence Angiography for Esophageal Reconstruction | unknown | N/A | 246 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Jun 9, 2020 | clinicaltrials |
| NCT02123381 | Changes in Tumor Tissue and Serum Biomarkers Before and After Cetuximab Combined With Preoperative Radiotherapy in Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 100 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Mar 17, 2020 | clinicaltrials |
| NCT03603756 | SHR-1210 in Combination With Apatinib and Chemotherapy in Patients With Advanced Esophageal Squamous Cell Cancer | unknown | Phase 2 | 45 | Chinese Academy of Medical SciencesOTHER | 1 | Feb 11, 2020 | clinicaltrials |
| NCT03913182 | Apatinib in the Treatment of Recurrence or Metastasis of Esophageal Cancer | unknown | Phase 2 | 39 | Shanghai Chest HospitalOTHER | 1 | Feb 5, 2020 | clinicaltrials |
| NCT04229537 | Study of SCT-I10A Combined SCT200 or SCT-I10A Combined SCT200 Plus Chemotherapy in ESCC and CRC | unknown | Phase 1 | 60 | Sinocelltech Ltd.INDUSTRY | 0 | Jan 18, 2020 | clinicaltrials |
| NCT04229849 | Anrotenib Plus Toripalimab Versus Toripalimab in Patients With Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 164 | Henan Cancer HospitalOTHER_GOV | 0 | Jan 18, 2020 | clinicaltrials |
| NCT04224363 | Whether it is More Appropriate to Spray Lugol's Solution From Cervical Esophagus to Esophagogastric Junction | unknown | N/A | 80 | Shandong UniversityOTHER | 0 | Jan 13, 2020 | clinicaltrials |
| NCT04006041 | Combination of Toripalimab and Neoadjuvant Chemoradiotherapy in Esophageal Cancer | unknown | Phase 2 | 44 | Jianhua FuOTHER | 1 | Dec 26, 2019 | clinicaltrials |
| NCT04170257 | Performance of White Light, NBI and Iodine Staining Endoscopy in the Diagnosis of Esophageal Lesions | unknown | N/A | 10,000 | Peking University Cancer Hospital & InstituteOTHER | 1 | Nov 20, 2019 | clinicaltrials |
| NCT04115618 | SIB in Upper Thoracic Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 65 | Fudan UniversityOTHER | 1 | Oct 4, 2019 | clinicaltrials |
| NCT03940001 | A Study of Sintilimab Plus Chemoradiation Before Surgery for Esophageal Cancer | unknown | Early Phase 1 | 20 | Zhejiang Cancer HospitalOTHER | 1 | Sep 9, 2019 | clinicaltrials |
| NCT04054518 | Durvalumab as Maintenance Following Chemoradiation for Unresectable Esophageal Squamous Cell Carcinoma(DESC) | unknown | Phase 2 | 22 | Tiago BiachiOTHER | 1 | Aug 13, 2019 | clinicaltrials |
| NCT03185988 | Anti-HER2 Therapy in Patients of HER2 Positive Metastatic Carcinoma of Digestive System | unknown | Phase 2 | 100 | Shen LinOTHER | 1 | Jul 19, 2019 | clinicaltrials |
| NCT03940976 | Afatinib in Previously Treated ESCC With EGFR Overexpression or EGFR Amplification (ESCC-A01) | unknown | Phase 2 | 40 | Peking UniversityOTHER | 1 | Jun 11, 2019 | clinicaltrials |
| NCT03927495 | KN046 in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 100 | Shanghai Chest HospitalOTHER | 1 | May 29, 2019 | clinicaltrials |
| NCT03922230 | Exploration and Verification of DNA Methylolation in Early Screening of Esophageal Cancer | unknown | — | 300 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Apr 19, 2019 | clinicaltrials |
| NCT02812641 | Neoadjuvant CCRT With/Without Bevacizumab for Locally Advanced ESCC | unknown | Phase 2 | 50 | National Taiwan University HospitalOTHER | 1 | Mar 11, 2019 | clinicaltrials |
| NCT03857763 | A Prospective Study of Apatinib Plus Concurrent Neoadjuvant Chemoradiotherapy in Patients With Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 40 | Hebei Medical University Fourth HospitalOTHER | 0 | Feb 28, 2019 | clinicaltrials |
| NCT03833466 | Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo)(ECMTPneo) | unknown | Phase 2 | 15 | Peking UniversityOTHER | 1 | Feb 15, 2019 | clinicaltrials |
| NCT02353936 | A Phase II Trial of Afatinib in Patients With Metastatic or Recurrent Squamous Cell Carcinoma of Esophagus | unknown | Phase 2 | 30 | Yonsei UniversityOTHER | 1 | Feb 11, 2019 | clinicaltrials |
| NCT03817567 | Safety and Efficacy of SCT200 in Patients With Advanced Esophageal Squamous Cell Carcinoma | unknown | Phase 1 / Phase 2 | 50 | Sinocelltech Ltd.INDUSTRY | 1 | Jan 25, 2019 | clinicaltrials |
| NCT03817658 | A Phase II Study of SHR-1210 vs Placebo as Consolidation Chemotherapy After Radical Concurrent Chemoradiotherapy in Locally Advanced ESCC | unknown | Phase 2 | 725 | The First Affiliated Hospital of Zhengzhou UniversityOTHER | 1 | Jan 25, 2019 | clinicaltrials |
| NCT03732508 | SHR-1316 in Combination With Chemotherapy in Patients With Esophageal Squamous Cell Cancer | unknown | Phase 2 | 30 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Nov 6, 2018 | clinicaltrials |
| NCT03585673 | Docetaxel-polymeric Micelles(PM) and Oxaliplatin for Esophageal Carcinoma(DOSE) | unknown | Phase 2 | 38 | Sung Yong OhOTHER | 1 | Jul 17, 2018 | clinicaltrials |
| NCT03273647 | Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma With Positive Circumstantial Resection Margin | unknown | Phase 3 | 60 | Fudan UniversityOTHER | 0 | Oct 19, 2017 | clinicaltrials |
| NCT02384811 | Phase II Study of Extensive Clinical Target Volumes in Postoperative Radiotherapy for Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 70 | Fudan UniversityOTHER | 1 | Sep 7, 2017 | clinicaltrials |
| NCT03224221 | Apatinib Combined With Chemotherapy for Esophageal Squamous Cell Cancer After the Failure of Standard Treatment | unknown | Phase 2 | 189 | The First Affiliated Hospital of Anhui Medical UniversityOTHER | 1 | Jul 21, 2017 | clinicaltrials |
| NCT02913066 | S-1 IMRT Versus S-1 and Cisplatin Concurrent IMRT in Inoperable Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 88 | Mianyang Central HospitalOTHER | 1 | Jun 16, 2017 | clinicaltrials |
| NCT00816634 | Efficacy Comparison Study of Combination Regimens to Treat Advanced Esophageal Squamous Cell Carcinoma(XP versus XT) | unknown | Phase 2 | 94 | Samsung Medical CenterOTHER | 1 | May 1, 2017 | clinicaltrials |
| NCT01216527 | Phase III Study of Neo-adjuvant Chemoradiotherapy Followed by Surgery for Squamous Cell Esophageal Cancer | unknown | Phase 3 | 430 | Sun Yat-sen UniversityOTHER | 1 | Feb 27, 2017 | clinicaltrials |
| NCT02604615 | The Role of Different Cycles of Chemotherapy（Capecitabine-oxaliplatin） in Esophageal Chemoradiotherapy(DCOECRT) | unknown | Phase 3 | 60 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Jul 6, 2016 | clinicaltrials |
| NCT02677597 | Cisplatin Combined With S-1 or Paclitaxel as First-line Treatment for Metastatic Esophageal Squamous Cell Carcinoma | unknown | Phase 3 | 268 | Fudan UniversityOTHER | 1 | Feb 9, 2016 | clinicaltrials |
| NCT02611700 | Nimotuzumab in Combined With Paclitaxel and Cisplatin for Treatment of Metastatic Esophageal Squamous Cell Carcinoma | unknown | Phase 3 | 504 | Biotech Pharmaceutical Co., Ltd.OTHER | 1 | Feb 1, 2016 | clinicaltrials |
| NCT02665702 | Endostar Combined With NVB and DDP Second-line Treatment of Advanced Esophageal Squamous Cell Carcinomas | unknown | Phase 2 | 76 | Fudan UniversityOTHER | 1 | Jan 28, 2016 | clinicaltrials |
| NCT02607540 | Different Cycles of Cisplatin-5-fluorouracil for the Chemoradiotherapy of Esophageal Squamous Cancer(PFCRTESC) | unknown | Phase 3 | 210 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Jan 12, 2016 | clinicaltrials |
| NCT02628665 | Clinical Study of Time Optimizing of Endoscopic Photodynamic Therapy on Esophageal and/or Gastric Cardiac Cancer | unknown | Phase 3 | 40 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Dec 11, 2015 | clinicaltrials |
| NCT02325986 | Concurrent Radiotherapy and Weekly Chemotherapy of PF for Postoperative Locoregional Recurrence of Esophageal Cancer | unknown | Phase 2 | 46 | Sun Yat-sen UniversityOTHER | 1 | Nov 20, 2015 | clinicaltrials |
| NCT02603159 | Different Cycles of Capecitabine Usage in Esophageal Cancer Concurrent Chemoradiotherapy(DCECRT) | unknown | Phase 3 | 200 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Nov 11, 2015 | clinicaltrials |
| NCT02586753 | Paclitaxel or S1 Plus Cisplatin in Concurrent Chemoradiotherapy for Squamous Cell Carcinoma of Esophagus | unknown | Phase 2 | 2 | Mianyang Central HospitalOTHER | 0 | Oct 26, 2015 | clinicaltrials |
| NCT02188615 | Study of Neo-adjuvant Chemoradiotherapy Followed by Minimally Invasive Esophagectomy for Squamous Cell Esophageal Cancer(NACRFMIE) | unknown | Phase 2 | 120 | Chengchu ZhuOTHER | 1 | Jul 11, 2014 | clinicaltrials |
| NCT02016274 | Sequential Paclitaxel Plus Cisplatin Chemotherapy and Radiotherapy as 1st Line Treatment for Esophageal Squamous Cell Cancer | unknown | Phase 2 | 70 | Shen LinOTHER | 1 | Dec 19, 2013 | clinicaltrials |
| NCT02016287 | Sequential Paclitaxel Chemotherapy and Radiotherapy as 1st Line Treatment for Elderly Esophageal Squamous Cell Cancer | unknown | Phase 2 | 50 | Shen LinOTHER | 1 | Dec 19, 2013 | clinicaltrials |
| NCT01993784 | Study of Nimotuzumab to Treat Esophageal Squamous Cell Carcinoma. | unknown | Phase 1 / Phase 2 | 9 | Peking UniversityOTHER | 1 | Nov 25, 2013 | clinicaltrials |
| NCT01688700 | Study of Nimotuzumab in Combination With Neoadjuvant Chemotherapy for Resectable Esophageal Squamous Cell Carcinoma | unknown | Phase 2 | 60 | Zhejiang Cancer HospitalOTHER | 1 | Sep 20, 2012 | clinicaltrials |
Data updated 23 days agoSource updated Nov 16, 2020source: clinicaltrials